Zobrazeno 1 - 10 of 341 pro vyhledávání: '"U, Diczfalusy"'
1
Akademický článek
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction?
Autor: I. Björkhem, A. Lövgren-Sandblom, F. Piehl, M. Khademi, H. Pettersson, V. Leoni, T. Olsson, U. Diczfalusy
Publikováno v: Journal of Lipid Research, Vol 52, Iss 1, Pp 170-174 (2011)
15-Oxygenated cholesterol species such as 5α-cholest-8(14)ene-3β,15α-diol (15HC) and 3β-hydroxy-5α-cholest-8(14)-en-15-one (15KC) are commercially available synthetic products unlikely to occur in biological systems. Surprisingly, Farez et al. r
Externí odkaz: https://doaj.org/article/4882768d8bf849e2a54b067106d3e352
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2
Akademický článek
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells
Autor: M P Ares, M I Pörn-Ares, J Thyberg, L Juntti-Berggren, P O Berggren, U Diczfalusy, B Kallin, I Björkhem, S Orrenius, J Nilsson
Publikováno v: Journal of Lipid Research, Vol 38, Iss 10, Pp 2049-2061 (1997)
We have characterized the death of human aortic smooth muscle cells induced by 25-hydroxycholesterol, an oxidation product of cholesterol. Chromatin condensation characteristic of apoptosis was observed by enzymatic (TUNEL) staining of chromatin, and
Externí odkaz: https://doaj.org/article/c5852a38e8eb4f50bd2b614f3ed47a1e
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3
Akademický článek
Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper
Autor: R P Patel, U Diczfalusy, S Dzeletovic, M T Wilson, V M Darley-Usmar
Publikováno v: Journal of Lipid Research, Vol 37, Iss 11, Pp 2361-2371 (1996)
Oxidation of low density lipoprotein (LDL) in the artery wall leads to the formation of cholesterol oxidation products that may result in cytotoxicity. Different mechanisms could contribute to LDL oxidation in vivo resulting in characteristic and spe
Externí odkaz: https://doaj.org/article/6559a1ae387644218205db97ce48e87e
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4
Akademický článek
Peroxisomal chain-shortening of thromboxane B2: evidence for impaired degradation of thromboxane B2 in Zellweger syndrome
Autor: U Diczfalusy, O Vesterqvist, BF Kase, E Lund, SE Alexson
Publikováno v: Journal of Lipid Research, Vol 34, Iss 7, Pp 1107-1113 (1993)
We have shown that rat liver peroxisomes can chain-shorten prostaglandins to dinor- and tetranor-metabolites. In a recent in vivo study we could demonstrate that peroxisomes are of major importance for chain-shortening of prostaglandin F2 alpha in hu
Externí odkaz: https://doaj.org/article/6a11a43d24084a8c85ebab50dfe5fced
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5
Akademický článek
Identification of metabolites from peroxisomal beta-oxidation of prostaglandins.
Autor: U Diczfalusy, SE Alexson
Publikováno v: Journal of Lipid Research, Vol 31, Iss 2, Pp 307-314 (1990)
We have recently shown that isolated rat liver peroxisomes can chain-shorten prostaglandin F2 alpha and prostaglandin E2 to tetranor-metabolites. In the present report dinor-metabolites of these two prostaglandins were also identified, suggesting tha
Externí odkaz: https://doaj.org/article/0df50525645146cc8e3eaf5b6907e6b9
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6
Akademický článek
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7
Akademický článek
Peroxisomal chain-shortening of prostaglandin F2 alpha.
Autor: U Diczfalusy, S E Alexson
Publikováno v: Journal of Lipid Research, Vol 29, Iss 12, Pp 1629-1636 (1988)
We have recently reported that prostaglandin F2 alpha can be chain-shortened by isolated rat liver peroxisomes. In the present study it is further established by cell fractionation experiments that the enzymes involved in this reaction are localized
Externí odkaz: https://doaj.org/article/4b904bd586cc488395ba1e7850158c9d
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10
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4
Autor: K, Bodin, L, Bretillon, Y, Aden, L, Bertilsson, U, Broomé, C, Einarsson, U, Diczfalusy
Publikováno v: The Journal of biological chemistry. 276(42)
The major cholesterol oxidation products in the human circulation are 27-hydroxycholesterol, 24-hydroxycholesterol, and 7alpha-hydroxycholesterol. These oxysterols are formed from cholesterol by specific cytochrome P450 enzymes, CYP27, CYP46, and CYP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::606f1fb8d3f3b5ee8ae6d862f339daeb
https://pubmed.ncbi.nlm.nih.gov/11514559
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