Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Tzyy Choou Wu"'
Autor:
Guiqin Xie, Liang Shan, Cuicui Yang, Yuanyi Liu, Xiaowu Pang, Shaolei Teng, Tzyy-Choou Wu, Xinbin Gu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The innate immune stimulator of interferon genes (STING) pathway is known to activate type I interferons (IFN-I) and participate in generating antitumor immunity. We previously produced hDT806, a recombinant diphtheria immunotoxin, and demon
Externí odkaz:
https://doaj.org/article/4c29c2a9b100442dad3224f3dddb2da3
Autor:
Ling Lim, Ming-Hung Hu, Darrell Fan, Hsin-Fang Tu, Ya-Chea Tsai, Michelle Cheng, Suyang Wang, Chih-Long Chang, Tzyy-Choou Wu, Chien-Fu Hung
Publikováno v:
Vaccines, Vol 12, Iss 4, p 430 (2024)
Human papillomavirus (HPV) remains a global health concern because it contributes to the initiation of various HPV-associated cancers such as anal, cervical, oropharyngeal, penile, vaginal, and vulvar cancer. In HPV-associated cancers, oncogenesis be
Externí odkaz:
https://doaj.org/article/2cd2e39bc759495aabab4f5acb4dd66c
Autor:
Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Ya Chea Tsai, Liangmei He, Gianni Castiglione, Emily Egbert, Elia J. Duh, Evan M. Bloch, Aaron A.R. Tobian, Aaron M. Milstone, Richard B.S. Roden, Tzyy-Choou Wu, Chien-Fu Hung
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109838- (2021)
Summary: As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads, variants with enhanced virulence and transmissibility have emerged. Although in vitro systems allow rapid characterization, they do not fully recapitulate the dynamic i
Externí odkaz:
https://doaj.org/article/71e3dc14b5b146a39a33944e1256682a
Publikováno v:
Biology, Vol 11, Iss 4, p 486 (2022)
Over 90% of head and neck squamous cell carcinoma (HNSCC) overexpresses the epidermal growth factor receptor (EGFR). However, the EGFR-targeted monotherapy response rate only achieves 10–30% in HNSCC. Recombinant immunotoxin (RIT) often consists of
Externí odkaz:
https://doaj.org/article/85bc0b1cf28c48669fdaaccfc12a3141
Autor:
Shengfeng Wan, Shengbo Cao, Xugang Wang, Yanfei Zhou, Weidong Yan, Xinbin Gu, Tzyy-Choou Wu, Xiaowu Pang
Publikováno v:
Vaccines, Vol 9, Iss 4, p 338 (2021)
The flavivirus Zika (ZIKV) has emerged as a global threat, making the development of a ZIKV vaccine a priority. While live-attenuated vaccines are known to induce long-term immunity but reduced safety, inactivated vaccines exhibit a weaker immune res
Externí odkaz:
https://doaj.org/article/9444a9fec1e445168b07597c4ae361c3
Autor:
Shengbo Cao, Xinbin Gu, Xiaowu Pang, Tzyy Choou Wu, Yanfei Zhou, Shengfeng Wan, Weidong Yan, Xugang Wang
Publikováno v:
Virology
Zika virus (ZIKV) is a mosquito-borne flavivirus that replicates in both vertebrate and insect cells, whereas insect-specific flaviviruses (ISF) replicate only in insect cells. We sought to convert ZIKV, from a dual-tropic flavivirus, into an insect-
Autor:
Chengbao Liu, Jessica Dillon, Yuehua Liu, Chien Fu Hung, Russell Vang, Tzyy Choou Wu, Anna Beavis, Kara Lombardo, Jairo E. Garcia, Deyin Xing, Amanda N. Fader
Publikováno v:
Histopathology. 76:354-365
Aims Hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome is caused by germline mutations in the Fumarate hydratase (FH) gene. In young women, the syndrome often presents with symptomatic uterine leiomyomas, leading to myomectomy or hyste
Autor:
Evan M. Bloch, Yu Jui Kung, John H. Lin, Tzyy Choou Wu, Liangmei He, Ya Chea Tsai, Ssu-Hsueh Tseng, Chien Fu Hung, Brandon Lam, Elia J. Duh, Gianni M Castiglione, Aaron M. Milstone, Aaron A.R. Tobian, Richard B. S. Roden, Emily R Egbert
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109838-(2021)
Cell Reports
Cell Reports
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads, variants with enhanced virulence and transmissibility have emerged. Although in vitro systems allow rapid characterization, they do not fully recapitulate the dynamic interactio
Autor:
Tae Heung Kang, Jayne Knoff, Wei-Hsi Yeh, Benjamin Yang, Chenguang Wang, Young Seob Kim, Tae Woo Kim, Tzyy-Choou Wu, Chien-Fu Hung
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103562 (2014)
Vitamin E has been shown to have strong anticarcinogenic properties, including antioxidant characteristics, making it an ideal candidate for use in combination with immunotherapies that modify the tumor microenvironment. The tumor microenvironment co
Externí odkaz:
https://doaj.org/article/6439f584d2b6418993e5f7aa64f17537
Autor:
Weidong Yan, Yanfei Zhou, Xinbin Gu, Shengbo Cao, Tzyy Choou Wu, Shengfeng Wan, Xugang Wang, Xiaowu Pang
Publikováno v:
Vaccines, Vol 9, Iss 338, p 338 (2021)
Vaccines
Volume 9
Issue 4
Vaccines
Volume 9
Issue 4
The flavivirus Zika (ZIKV) has emerged as a global threat, making the development of a ZIKV vaccine a priority. While live-attenuated vaccines are known to induce long-term immunity but reduced safety, inactivated vaccines exhibit a weaker immune res