Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tzvi Aviv"'
Publikováno v:
Canadian Journal of Diabetes. 46:S22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54011ec433daeaa2be3bf9b6a869bdd8
https://doi.org/10.1016/j.jcjd.2022.09.061
https://doi.org/10.1016/j.jcjd.2022.09.061
Publikováno v:
Nature. 600:386-386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::457cac91d16c2ae143cee64e69f99a84
https://doi.org/10.1038/d41586-021-03696-9
https://doi.org/10.1038/d41586-021-03696-9
Autor:
Hayden J. Selvadurai, Xiaoyang Lan, Michelle Kushida, Sonam Dolma, Lea Harrington, Tzvi Aviv, Xueming Zhu, Peter B. Dirks, Lilian Lee, Heather Whetstone, Katherine J. Rowland, Renee Head, Ian D. Clarke, Mike Tyers, Milly So, Changjiang Xu, Gary D. Bader, Mark Bernstein, John H. Brumell, Veronique Voisin, Nicole I. Park
Publikováno v:
Cancer Cell. 29:859-873
Glioblastomas (GBM) grow in a rich neurochemical milieu, but the impact of neurochemicals on GBM growth is largely unexplored. We interrogated 680 neurochemical compounds in patient-derived GBM neural stem cells (GNS) to determine the effects on prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51bb2079e08fbfebcb103c60edd1f3e
https://doi.org/10.1016/j.ccell.2016.05.002
https://doi.org/10.1016/j.ccell.2016.05.002
Publikováno v:
Nature Structural & Molecular Biology. 13:168-176
The SAM domain of the Saccharomyces cerevisiae post-transcriptional regulator Vts1p epitomizes a subfamily of SAM domains conserved from yeast to humans that function as sequence-specific RNA-binding domains. Here we report the 2.0-A X-ray structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f5cec812b28e00a84bd21ae7d04bc0
https://doi.org/10.1038/nsmb1053
https://doi.org/10.1038/nsmb1053
Publikováno v:
Nature Structural & Molecular Biology. 10:614-621
Anteroposterior patterning in Drosophila melanogaster is dependent on the sequence-specific RNA-binding protein Smaug, which binds to and regulates the translation of nanos (nos) mRNA. Here we demonstrate that the sterile-alpha motif (SAM) domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f283765caac5cae4e587aff9ce780c0c
https://doi.org/10.1038/nsb956
https://doi.org/10.1038/nsb956
Autor:
Jenny Q. Qian, Darell D. Bigner, Miklós Garami, Shaun D. Jackman, Wiesława Grajkowska, Nalin Gupta, Johan M. Kros, Poul H. Sorensen, Anna Kenney, Stéphanie Reynaud, Byung Kyu Cho, Ian F. Pollack, Marcel Kool, Steven C. Clifford, Kyu-Chang Wang, Inanc Birol, Tzvi Aviv, Hendrick Witt, Gemma Hoad, Martine F. Roussel, Christine Haberler, Pim J. French, Betty Luu, Cynthia Hawkins, Claudia C. Faria, Richard A. Moore, Karin M. Muraszko, Yuan Yao, Nanne K. Kloosterhof, Rameen Beroukhim, Leos Kren, Erna M.C. Michiels, Jan O. Korbel, Paul A. Northcott, Stefan M. Pfister, Marc Remke, Nina Thiessen, Jennifer A. Chan, Adam M. Fontebasso, Maryam Fouladi, Shin Jung, Richard G. Ellenbogen, Richard Corbett, László Bognár, Yoon Jae Cho, Massimo Zollo, Robert J. Wechsler-Reya, Steven E. Schumacher, Xing Fan, Michael J. Levy, Wolfram Scheurlen, Young Shin Ra, Adrian M. Stütz, William A. Weiss, Simon Bailey, Rajeev Vibhakar, Giuseppe Cinalli, Toshihiro Kumabe, Marco A. Marra, Christian R. Marshall, Eric Bouffet, Luca Massimi, Scott L. Pomeroy, Sarah S. Pernet-Fattet, Andrew J. Mungall, James T. Rutka, G. Yancey Gillespie, Charles G. Eberhart, Peter Hauser, Andy Chu, Jüri Reimand, Xiaochong Wu, Adi Rolider, Xin Wang, Stephen W. Scherer, Reid C. Thompson, Ka Ming Nip, Anne Jouvet, Timothy E. Van Meter, Robert A. Holt, Anthony Raymond, Livia Garzia, Teiji Tominaga, Erwin G. Van Meir, John Peacock, Michael D. Taylor, Achille Iolascon, Roger E. McLendon, Andrey Korshunov, Stephen C. Mack, Nada Jabado, Readman Chiu, Africa Fernandez-L, Eric Chuah, Richard Varhol, Hideo Nakamura, Samer K. Elbabaa, Uri Tabori, Peter B. Dirks, Gary D. Bader, Linda M. Liau, François Doz, Allan Lo, Janet C. Lindsey, Adrian M. Dubuc, Michelle Fèvre-Montange, David T.W. Jones, Carlos Gilberto Carlotti, Ali G. Saad, Steffen Albrecht, Michael K. Cooper, Karen Mungall, Daisuke Kawauchi, A. Sorana Morrissy, Boleslaw Lach, Karel Zitterbart, Joshua B. Rubin, Matthew Meyerson, Florence M.G. Cavalli, Yisu Li, Shenandoah Robinson, Marta Perek-Polnik, Olivier Delattre, David Malkin, Almos Klekner, James M. Olson, Steven J.M. Jones, Thomas Zichner, David W. Ellison, Seung-Ki Kim, Vijay Ramaswamy, Anath C. Lionel, David Shih, Jeffrey R. Leonard, Concezio Di Rocco
Publikováno v:
Nature, 488(7409), 49-56. Nature Publishing Group
Nature, vol. 488, no. 7409, pp. 49-56
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature, vol. 488, no. 7409, pp. 49-56
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits marked intertumoural hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c0bed20006ff67a402d4b2087b84fc
https://pure.eur.nl/en/publications/e92d8a69-c09e-47f4-8909-50517a3013ba
https://pure.eur.nl/en/publications/e92d8a69-c09e-47f4-8909-50517a3013ba
Autor:
X. Sharon Zhao, Andrew N. Amborski, Jamie J. Kwan, Logan W. Donaldson, Philip E. Johnson, Frank Sicheri, Tzvi Aviv
Publikováno v:
Journal of molecular biology. 356(2)
The SAM domain of the Saccharomyces cerevisiae post-transcriptional regulator Vts1 has a high affinity towards RNA hairpins containing a CUGGC pentaloop. We present the 1.6 Angstroms X-ray crystal structure of the Vts1 SAM domain in its unliganded st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33274cd0bc72c24445c12ee3d917870
https://pubmed.ncbi.nlm.nih.gov/16375924
https://pubmed.ncbi.nlm.nih.gov/16375924
Autor:
Marcel Kool, Fiona J. Coutinho, Marco A. Marra, Stefan M. Pfister, Xueming Zhu, Andrey Korshunov, Peter B. Dirks, Yussanne Ma, Renee Head, Marco Gallo, David Malkin, Steven J.M. Jones, Gary D. Bader, Veronique Voisin, Sorana Morrissy, Ian D. Clarke, Andrew J. Mungall, Marc Remke, Michael D. Taylor, Richard A. Moore, Tzvi Aviv, Yisu Li, Hayden J. Selvadurai, Lilian Lee, Paul A. Northcott, Robert Vanner, Konrad Hochedlinger, Michelle Kushida
Publikováno v:
Cancer Cell. (1):33-47
SummaryFunctional heterogeneity within tumors presents a significant therapeutic challenge. Here we show that quiescent, therapy-resistant Sox2+ cells propagate sonic hedgehog subgroup medulloblastoma by a mechanism that mirrors a neurogenic program.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fc8a3b26c4dee5f736eacb408f7930