Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy.

Autor: Tzuri N; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and The National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel., Yegodayev KM; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel., Novoplansky O; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel., Elkabets M; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel., Aharoni A; Department of Life Sciences and The National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel., Papo N; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and The National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel. papo@bgu.ac.il.

Publikováno v: Scientific reports [Sci Rep] 2023 Jul 24; Vol. 13 (1), pp. 11923. Date of Electronic Publication: 2023 Jul 24.

Engineered in vivo and in vitro tumor model recapitulates vasculogenic mimicry signatures in melanoma.

Autor: Shuai, Qizhi¹ (AUTHOR) shuaiqizhi@sxmu.edu.cn, Xu, Xinrui^1,2 (AUTHOR), Liang, Yuxiang^1,3 (AUTHOR), Halbiyat, Zulala¹ (AUTHOR), Lu, Xin¹ (AUTHOR), Hu, Zixuan¹ (AUTHOR), Peng, Zhiwei¹ (AUTHOR), An, Jie⁴ (AUTHOR), Feng, Zhiwei¹ (AUTHOR), Huang, Tingjuan¹ (AUTHOR), Zhao, Hong¹ (AUTHOR), Liu, Zhizhen¹ (AUTHOR) zhizhenliu2013@163.com, Xu, Jun⁵ (AUTHOR) junxuty@163.com, Xie, Jun¹ (AUTHOR) junxie@sxmu.edu.cn

Publikováno v: Bioengineering & Translational Medicine. Jul2024, Vol. 9 Issue 4, p1-17. 17p.

Investigation of genetic diversity of squash (Cucurbita maxima Duchesne) genotypes collected from Erzincan in Turkey.

Autor: BULUT, Hüseyin¹, ÖZTÜRK, Halil İbrahim¹ hiozturk@erzincan.edu.tr, DÖNDERALP, Veysel², KORKUT, Recep², DURSUN, Atilla^3,4

Publikováno v: Taiwania. 2022, Vol. 67 Issue 4, p469-478. 10p.

Functional Characterization and Protein Engineering of a Triterpene 3‐/6‐/2′‐O‐Glycosyltransferase Reveal a Conserved Residue Critical for the Regiospecificity.

Autor: Zhang, Meng¹ (AUTHOR), Yi, Yang¹ (AUTHOR), Gao, Bai‐Han¹ (AUTHOR), Su, Hui‐Fei¹ (AUTHOR), Bao, Yang‐Oujie¹ (AUTHOR), Shi, Xiao‐Meng¹ (AUTHOR), Wang, Hai‐Dong¹ (AUTHOR), Li, Fu‐Dong² (AUTHOR), Ye, Min¹ (AUTHOR) yemin@bjmu.edu.cn, Qiao, Xue¹ (AUTHOR) qiaoxue@bjmu.eu.cn

Publikováno v: Angewandte Chemie. 2/14/2022, Vol. 134 Issue 8, p1-11. 11p.

Antiangiogenic-immune-checkpoint inhibitor combinations: lessons from phase III clinical trials.

Autor: Kuo HY; Department of Oncology, National Taiwan University Hospital, and Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. hykuo@ntuh.gov.tw., Khan KA; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario, Canada. kkhan@sri.utoronto.ca.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. kkhan@sri.utoronto.ca., Kerbel RS; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario, Canada. Robert.kerbel@sri.utoronto.ca.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. Robert.kerbel@sri.utoronto.ca.

Publikováno v: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2024 Jun; Vol. 21 (6), pp. 468-482. Date of Electronic Publication: 2024 Apr 10.