Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Tzu-Ying Sung"'
Autor:
Chao-Di Chang, Min-Wu Chao, Hsueh-Yun Lee, Yi-Ting Liu, Huang-Ju Tu, Ssu-Ting Lien, Tony Eight Lin, Tzu-Ying Sung, Shih-Chung Yen, Sing-Han Huang, Kai-Cheng Hsu, Shiow-Lin Pan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes. By pho
Externí odkaz:
https://doaj.org/article/eeb87040e05f48b3ad27fb6a79897905
Autor:
Jui-Yi Hsu, Kai-Cheng Hsu, Ching Sun, Ching-Hsuan Chou, Tony Eight Lin, Tzu-Ying Sung, Hui-Ju Tseng, Shih-Chung Yen, Chia-Ron Yang, Wei-Jan Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114258- (2023)
Cyclin-dependent protein kinase 8 (CDK8) plays important roles in regulating fibrotic growth factors and inflammatory signaling pathways. Long-term chronic inflammation of the lungs can lead to idiopathic pulmonary fibrosis (IPF). Abnormal alveolar e
Externí odkaz:
https://doaj.org/article/69ee12bcfc574e07acf7e07b3ddb8146
Autor:
Tony Eight Lin, Li-Chin Sung, Min-Wu Chao, Min Li, Jia-Huei Zheng, Tzu-Ying Sung, Jui-Hua Hsieh, Chia-Ron Yang, Hsueh-Yun Lee, Er-Chieh Cho, Kai-Cheng Hsu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 226-235 (2022)
Bruton tyrosine kinase (BTK) is linked to multiple signalling pathways that regulate cellular survival, activation, and proliferation. A covalent BTK inhibitor has shown favourable outcomes for treating B cell malignant leukaemia. However, covalent i
Externí odkaz:
https://doaj.org/article/4eee7f20c593416abeb5853c9de04c92
Autor:
Min-Wu Chao, Tony Eight Lin, Wei-Chun HuangFu, Chao-Di Chang, Huang-Ju Tu, Liang-Chieh Chen, Shih-Chung Yen, Tzu-Ying Sung, Wei-Jan Huang, Chia-Ron Yang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 98-108 (2021)
The STE20 kinase family is a complex signalling cascade that regulates cytoskeletal organisation and modulates the stress response. This signalling cascade includes various kinase mediators, such as TAOK1 and MAP4K5. The dysregulation of the STE20 ki
Externí odkaz:
https://doaj.org/article/a23f5c3bf07c4ef483bac5eb846abc10
Autor:
Tony Eight Lin, Chia-Ron Yang, Ching-Hsuan Chou, Jui-Yi Hsu, Min-Wu Chao, Tzu-Ying Sung, Jui-Hua Hsieh, Wei-Jan Huang, Kai-Cheng Hsu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112459- (2022)
Chronic inflammation is an underlying cause in a number of diseases. Cyclin-dependent kinase 8 (CDK8) has been implicated as an inflammatory mediator, indicating its potential as an anti-inflammatory target. Herein, we performed structure-based virtu
Externí odkaz:
https://doaj.org/article/0571fe428d584aff829c19f8da7aaa05
Autor:
Tony Eight Lin, Min-Wu Chao, Wei-Chun HuangFu, Huang-Ju Tu, Zhao-Xiang Peng, Chih-Jou Su, Tzu-Ying Sung, Jui-Hua Hsieh, Cheng-Chung Lee, Chia-Ron Yang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112580- (2022)
The dysregulation of DYRK1A is implicated in many diseases such as cancer, diabetes, and neurodegenerative diseases. Alzheimer’s disease is one of the most common neurodegenerative disease and has elevated interest in DYRK1A research. Overexpressio
Externí odkaz:
https://doaj.org/article/bde6aaca1032477f872fda9997782694
Autor:
Shashi Kant Singh, Tzu-Ying Sung, Tsui-Yun Chung, Shao-Yu Lin, Sang-Chu Lin, Jo-Chien Liao, Wei-Yu Hsieh, Ming-Hsiun Hsieh
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract The ACT domain (aspartate kinase, chorismate mutase and TyrA), an allosteric effector binding domain, is commonly found in amino acid metabolic enzymes. In addition to ACT domain-containing enzymes, plants have a novel family of ACT domain r
Externí odkaz:
https://doaj.org/article/8ef539a3f5f944f0b2640f3ec0334312
Autor:
Kai-Cheng Hsu, Chang-Yi Liu, Tony Eight Lin, Jui-Hua Hsieh, Tzu-Ying Sung, Hui-Ju Tseng, Jinn-Moon Yang, Wei-Jan Huang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Histone deacetylases (HDAC) contain eighteen isoforms that can be divided into four classes. Of these isoform enzymes, class IIa (containing HDAC4, 5, 7 and 9) target unique substrates, some of which are client proteins associated with epige
Externí odkaz:
https://doaj.org/article/7b99dbc22d7541d3950827cebd4867ae
Autor:
Tony Eight Lin, Wei-Chun HuangFu, Min-Wu Chao, Tzu-Ying Sung, Chao-Di Chang, Yi-Ying Chen, Jui-Hua Hsieh, Huang-Ju Tu, Han-Li Huang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the path
Externí odkaz:
https://doaj.org/article/53feeaf4e47a4482ada47bbc6e155336
Autor:
Tzu-Ying Sung, 宋姿瑩
99
The medical tourism industry is globally recognized as one of the fastest growing market sectors today. Medical tourism combines lower-cost medical procedures with the patient’s desire to enjoy tourism in the locale providing such health ca
The medical tourism industry is globally recognized as one of the fastest growing market sectors today. Medical tourism combines lower-cost medical procedures with the patient’s desire to enjoy tourism in the locale providing such health ca
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/45289932387694113809
