Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Tzu-Lin Sun"'
Autor:
Tzu-Lin Sun, 孫梓凌
95
Hepatic disease has always been a major health problem in Taiwan, with hepatocellular carcinoma (HCC) being among the leading causes of death. Since the diagnosis of the degree of liver carcinoma is done according to the doctor’s clinical e
Hepatic disease has always been a major health problem in Taiwan, with hepatocellular carcinoma (HCC) being among the leading causes of death. Since the diagnosis of the degree of liver carcinoma is done according to the doctor’s clinical e
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/07202054331048812761
Autor:
Tzu-Lin Sun, Su‐Yen Lo, Chen-Yuan Dong, Yu-Yang Lee, Wei-Liang Chen, Sheng-Shun Wang, Chih-Ju Lin, Hsuan-Shu Lee, Nicholas G. Horton, Feng-Chieh Li, Sheng-Lin Lee, Hung-Ming Lin, Shu-Jen Chiang, Yang-Fang Chen, Wen Lo, Chris Xu
Publikováno v:
Journal of Biophotonics. 12
Acetaminophen (APAP) overdose is one of the world's leading causes of drug-induced hepatotoxicity. Although traditional methods such as histological imaging and biochemical assays have been successfully applied to evaluate the extent of APAP-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35e4360e601972e3f75f5934324881b
https://doi.org/10.1002/jbio.201800296
https://doi.org/10.1002/jbio.201800296
Autor:
Huey W. Huang, James A. McNew, Tyler J. Moss, Idil Ulengin, Tzu-Lin Sun, Avani Verma, Joseph E. Faust, Miguel A. Betancourt-Solis, Tanvi Desai, Tina Lee
Publikováno v:
Journal of Biological Chemistry. 290:4772-4783
Fusion of tubular membranes is required to form three-way junctions found in reticular subdomains of the endoplasmic reticulum. The large GTPase Atlastin has recently been shown to drive endoplasmic reticulum membrane fusion and three-way junction fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db64422c3b0421ae9f6ef041f9b63157
https://doi.org/10.1074/jbc.m114.601823
https://doi.org/10.1074/jbc.m114.601823
Publikováno v:
Biophysical Journal. 107:2082-2090
We investigated the physical properties of bacterial cytoplasmic membranes by applying the method of micropipette aspiration to Escherichia coli spheroplasts. We found that the properties of spheroplast membranes are significantly different from that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3f369fcdb30d58a9e5dfd1e7ce9fd4
https://doi.org/10.1016/j.bpj.2014.09.034
https://doi.org/10.1016/j.bpj.2014.09.034
Publikováno v:
Biochemistry
Daptomycin is the first approved member of a new structural class of antibiotics, the cyclic lipopeptides. The peptide interacts with the lipid matrix of cell membranes, inducing permeability of the membrane to ions, but its molecular mechanism has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cba20151ef3a610979ca6705177dc3
http://europepmc.org/articles/PMC4148140
http://europepmc.org/articles/PMC4148140
Publikováno v:
Biophysical Journal. 104(9):1923-1932
Schafmeister, Po, and Verdine (another study) introduced a method using a hydrocarbon linker (staple) to stabilize a peptide in a helical configuration. One intended goal of this scheme is to facilitate the delivery of peptide drugs into target cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efe8af6b54cdbd1e594804cfdf4ec0a
Autor:
Sen Chang Yu, Chieh Wen Lai, Tzu-Lin Sun, Yao Jen Chang, Chao Chuan Wu, Lee Wei Chen, Wen Lo, Zong Han Tang, Chen-Yuan Dong, Semon Wu
Publikováno v:
Journal of Trauma and Acute Care Surgery. 74:203-213
Background The intestinal mucosa exhibits high turnover rates with a balance of shedding and the migration of epithelial cells to maintain gut barrier function. Systemic diseases such as sepsis and major thermal injury accelerate the rate of cell she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718d8e10f0b2c443da202bc9456348f1
https://doi.org/10.1097/ta.0b013e3182788083
https://doi.org/10.1097/ta.0b013e3182788083
Publikováno v:
Biophysical Journal. 110(3)
One fundamental issue in the field of AMPs has been whether the action of AMPs produces pores in the membranes or disintegrates the membranes by the saturated surface binding of AMPs (the carpet model). In the absence of clear evidence, either mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87eaab79c7797c4f4dea565ca2691f2
Autor:
Tzu-Lin Sun, Guan-Tarn Huang, Jhih-Huei Liang, Hsuan-Shu Lee, Ling-Ling Chiou, Feng-Chieh Li, Yuan Liu, Chen-Yuan Dong
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 296:G1091-G1097
We tried to image obstructive cholestasis by using a newly developed imaging system to measure the alterations of hepatobiliary function in living mice with their bile ducts ligated. A hepatic imaging window was installed on the upper abdomen soon af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e34136628e0e31ada9651889d202870
https://doi.org/10.1152/ajpgi.90681.2008
https://doi.org/10.1152/ajpgi.90681.2008
Publikováno v:
Biophysical Journal. 104(2)
Daptomycin is a clinically important 13 amino acid lipopeptide antibiotic. Its N-terminus is acylated with n-decanol and its C-terminal 10 amino acids form a ring. It is structurally and size-wise different from other well-known membrane-active antim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee9bcf55fb848dfbfc47c701d1ee951