Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tzu-I Chao"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11092 (2022)
Ferroptosis is a type of iron-dependent cell death pertaining to an excess of lipid peroxidation. It has been suggested that sorafenib—an anti-angiogenic medication for hepatocellular carcinoma (HCC)—induces ferroptosis, but the underlying mechan
Externí odkaz:
https://doaj.org/article/aaab40bcdd1643758e94b788b75d02c5
Autor:
Chung Wai Shiau, Man Hsin Hung, Chao-Yuan Huang, Chi Ting Shih, Yen-Lin Chen, Tzu I. Chao, Li-Ju Chen, Kuen-Feng Chen, Cheng Yi Wang
Publikováno v:
Cancer Letters. 498:142-151
Recent advances in immune checkpoint inhibition, which augment T-cell immune responses, have highlighted the potential of exploiting one's immune system to combat cancer. However, only a relatively small number of non-small cell lung cancer (NSCLC) p
Autor:
Chiung-Wen Kuo, Shih-Shin Chang, Li-Ju Chen, Kuen-Feng Chen, Cheng-Yi Wang, Ming-Hsien Tsai, Man-Hsin Hung, Chao-Yuan Huang, Feng-Shu Hsieh, Tzu-I Chao, Chi-Ting Shih
Publikováno v:
European Journal of Cancer. 102:10-22
Aim Palbociclib is an oral cyclin-dependent kinase 4/6 inhibitor, which is efficacious in treating breast cancer. Currently, there are numerous active clinical trials testing palbociclib alone or in combination with other medications for treating var
Autor:
Man-Hsin Hung, Tzu-I Chao, Feng-Shu Hsieh, Ming-Hsien Tsai, Li-Ju Chen, Kuen-Feng Chen, Chi-Ting Shih, Chiung-Wen Kuo, Shih-Shin Chang, Yung-Jen Hsiao, Chao-Yuan Huang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 366:410-421
Increasing evidence suggests that SET functions as an oncoprotein and promotes cancer survival and therapeutic resistance. However, whether SET affects radiation therapy (RT)-mediated anticancer effects has not yet been explored. We investigated the
Autor:
Tzu Ting Huang, Yen-Lin Chen, Tzu I. Chao, Ming-Hsien Tsai, Ming Hung Hu, Chunyu Liu, Jia-Horng Kao, Kuen-Feng Chen, Li-Ju Chen
Publikováno v:
Liver International. 38:2248-2259
Background & aims Few molecules are currently verified to be actionable drug targets in cholangiocarcinoma (CCA). Serine/threonine protein phosphatase 5 (PP5) dysregulation is related to several malignancies. However, the role of PP5 in CCA is poorly
Autor:
Jung Chen Su, Kuen-Feng Chen, Ling Ming Tseng, Chia Han Lee, Ka Yi Lau, Pei-Yi Chu, Ming Huang Chen, Chung Wai Shiau, Chunyu Liu, Hsiu Ping Yang, Tzu I. Chao, Chun Teng Huang, Wan-Lun Wang, Chia Yun Wu, Tzu Ting Huang, Wen Chun Tsai
Publikováno v:
Journal of Molecular Medicine. 95:965-975
Triple negative breast cancer (TNBC) is an aggressive cancer for which prognosis remains poor. Combination therapy is a promising strategy for enhancing treatment efficacy. Blockade of STAT3 signaling may enhance the response of cancer cells to conve
Autor:
Yen-Lin Chen, Tzu I. Chao, Chung Wai Shiau, Ming Hung Hu, Chunyu Liu, Li-Ju Chen, Kuen-Feng Chen, Jia-Horng Kao, Ming Shen Tsai
Publikováno v:
Oncotarget
// Ming-Hung Hu 3, 4, 5 , Li-Ju Chen 1 , Yen-Lin Chen 7 , Ming-Shen Tsai 1 , Chung-Wai Shiau 8 , Tzu-I Chao 9 , Chun-Yu Liu 6, 10 , Jia-Horng Kao 3, 11 and Kuen-Feng Chen 1, 2 1 Department of Medical Research, National Taiwan University Hospital, Tai
Autor:
Yao Li Chen, Chung Wai Shiau, Pei-Yi Chu, Yung Jen Hsiao, Li-Ju Chen, Tzu I. Chao, Mao Ju Chang, Kuen-Feng Chen, Chih Ting Shih, Ming-Hsien Tsai, Feng Shu Hsieh, Man Hsin Hung
Publikováno v:
Molecular Oncology
Palbociclib, a CDK4/6 inhibitor, has recently been approved for hormone receptor-positive breast cancer patients. The effects of palbociclib as a treatment for other malignancies, including hepatocellular carcinoma (HCC), are of great clinical intere
Autor:
Kuen-Feng Chen, Yao-Li Chen, Chih-Ting Shih, Feng-Shu Hsieh, Ming-Hsien Tsai, Li-Ju Chen, Chao-Yuan Huang, Man-Hsin Hung, Pei-Yi Chu, Tzu-I Chao
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 6, Pp 1-15 (2019)
Cell Death and Disease, Vol 10, Iss 6, Pp 1-15 (2019)
Accelerated glucose metabolism is critical in hepatocarcinogenesis, but the utilities of different glucose transporter inhibitors in treating hepatocellular carcinoma (HCC) remain largely uncharacterized. In this study, we examined a collection of gl
Autor:
Ming-Hsien Tsai, Jia-Rong Li, Tzu-I Chao, Kuen-Feng Chen, Cheng-Yi Wang, Yen-Lin Chen, Chih-Ting Shih, Yung-Jen Hsiao, Feng-Shu Hsieh, Li-Ju Chen, Man-Hsin Hung
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 112
Objectives Non-small cell lung cancer (NSCLC) continues to be the top cause of cancer death. To improve the treatment of lung cancer, there is necessity to identify novel oncogenes and investigate their effects on lung carcinogenesis. Protein phospha