Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tzu-Chieh Ho"'
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 241-252 (2023)
We propose an ex vivo T cell expansion system that mimics natural antigen-presenting cells (APCs) for adoptive cell therapy (ACT). Microfiber scaffolds coated with dendritic cell (DC) membrane replicate physicochemical properties of dendritic cells s
Externí odkaz:
https://doaj.org/article/0906ac8908a34bbaaface5029651fdba
Autor:
Hanyao Huang, Weiyi Pan, Yifan Wang, Hye Sung Kim, Dan Shao, Baoding Huang, Tzu-Chieh Ho, Yeh-Hsing Lao, Chai Hoon Quek, Jiayu Shi, Qianming Chen, Bing Shi, Shengmin Zhang, Lei Zhao, Kam W. Leong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Periodontitis is a common type of inflammatory bone loss, and cell-free DNA (cfDNA) can be a major source that enhances the periodontal tissue destruction. Here, the authors show that a cfDNA-scavenging approach is able to ameliorate periodontitis by
Externí odkaz:
https://doaj.org/article/93703e2f9a7c40a7b3a4f9319e5fd435
Autor:
Biniam Adane, Haobin Ye, Nabilah Khan, Shanshan Pei, Mohammad Minhajuddin, Brett M. Stevens, Courtney L. Jones, Angelo D’Alessandro, Julie A. Reisz, Vadym Zaberezhnyy, Maura Gasparetto, Tzu-Chieh Ho, Kathleen K. Kelly, Jason R. Myers, John M. Ashton, Julie Siegenthaler, Tsutomu Kume, Eric L. Campbell, Daniel A. Pollyea, Michael W. Becker, Craig T. Jordan
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 238-254.e6 (2019)
Summary: The NADPH-dependent oxidase NOX2 is an important effector of immune cell function, and its activity has been linked to oncogenic signaling. Here, we describe a role for NOX2 in leukemia-initiating stem cell populations (LSCs). In a murine mo
Externí odkaz:
https://doaj.org/article/d5544c2b5ce54bd09d30079612acafba
Autor:
James Taggart, Tzu-Chieh Ho, Elianna Amin, Haiming Xu, Trevor S. Barlowe, Alexendar R. Perez, Benjamin H. Durham, Patrick Tivnan, Rachel Okabe, Arthur Chow, Ly Vu, Sun Mi Park, Camila Prieto, Christopher Famulare, Minal Patel, Christopher J. Lengner, Amit Verma, Gail Roboz, Monica Guzman, Virginia M. Klimek, Omar Abdel-Wahab, Christina Leslie, Stephen D. Nimer, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Several studies have recently demonstrated the role of the MSI2 RNA binding protein in normal and malignant haematopoietc stem cells. In this study, the authors show that MSI2 is required for maintaining myelodysplastic syndrome stem cells in mice an
Externí odkaz:
https://doaj.org/article/3c73f9725b9740dfbe30b10dcaac4d49
Autor:
Tzu-Chieh Ho, 何子潔
90
When treated with heavy metal (Cd), Plant produces phytochelatin (PC) for the sequestration of the toxic metals. PC has the general structure of (g-Glu-Cys)n-Gly (n = 2~11, PCn), and forms a lower molecular weight complex (LMW) with Cd first
When treated with heavy metal (Cd), Plant produces phytochelatin (PC) for the sequestration of the toxic metals. PC has the general structure of (g-Glu-Cys)n-Gly (n = 2~11, PCn), and forms a lower molecular weight complex (LMW) with Cd first
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/85536893933024741098
Autor:
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J. Fountaine, Daniel K Byun, Mark W. LaMere, Jason H. Mendler, Tzu-Chieh Ho, Noah A. Salama, Benjamin J. Frisch, Jason R. Myers, Siba El Hussein, John M. Ashton, Mitra Azadniv, Jane L. Liesveld, Youmna Kfoury, David T. Scadden, Michael W. Becker, Laura M. Calvi
SUMMARYMesenchymal stem/stromal cells (MSCs) within the bone marrow microenvironment (BMME) support normal hematopoietic stem and progenitor cells (HSPCs). However, the heterogeneity of human MSCs has limited the understanding of their contribution t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1620cde45bc77078164157cecacc53e6
https://doi.org/10.1101/2023.04.09.536176
https://doi.org/10.1101/2023.04.09.536176
Autor:
Noah Salama, Olivia Lynch, Emily R Quarato, Yuko Kawano, Benjamin Rodems, Eric Cefaloni, Tzu-Chieh Ho, Kathleen E. McGrath, Michael W. Becker, Jane L. Liesveld, Paula M Vertino, James Palis, Jeevisha Bajaj, Laura M. Calvi
Publikováno v:
Blood. 140:9757-9758
Publikováno v:
Bioactive materials. 21
We propose an ex vivo T cell expansion system that mimics natural antigen-presenting cells (APCs) for adoptive cell therapy (ACT). Microfiber scaffolds coated with dendritic cell (DC) membrane replicate physicochemical properties of dendritic cells s
Autor:
Michael W. Becker, Yamin Li, Yumei Chen, Qiaobing Xu, Tzu-Chieh Ho, Mark W. LaMere, Kam W. Leong, John M. Ashton, Hae-Won Kim, Haiyan Wang, Hye Sung Kim, Caroline Chen, Jing Gong, Cal D. Palumbo
Publikováno v:
Science Advances
A scaffold-mediated system was developed to enhance the local delivery of Cas9 complexes for targeting leukemia stem cells in AML.
Leukemia stem cells (LSCs) sustain the disease and contribute to relapse in acute myeloid leukemia (AML). Therapie
Leukemia stem cells (LSCs) sustain the disease and contribute to relapse in acute myeloid leukemia (AML). Therapie
Autor:
Shih-Lan Hsu, Chieh-Lin Jerry Teng, Jia-Rong Tsai, Tzu-Hung Hsiao, Tzu-Chieh Ho, Li-Ju Wang, Yu-Chiao Chiu
Publikováno v:
European Journal of Haematology. 103:417-425
OBJECTIVES This study explored resistance functions and their interactions in de novo AML treated with the "7 + 3" induction regimen. METHODS We analyzed RNA-sequencing profiles of whole bone marrow samples from 52 de novo AML patients who completed