Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Tzu Jen Kao"'
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment options, such as the chemotherapeutic agent, temozolomide (TMZ). However, many GBM tumors develop resistance to TMZ, which is a major obstacle to effecti
Externí odkaz:
https://doaj.org/article/ba2167d4f6014e08979784f9b1de8631
Autor:
Yu-Ting Tsai, Wei-Lun Lo, Pin-Yuan Chen, Chiung-Yuan Ko, Jian-Ying Chuang, Tzu-Jen Kao, Wen-Bing Yang, Kwang-Yu Chang, Chia-Yang Hung, Ushio Kikkawa, Wen-Chang Chang, Tsung-I. Hsu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Background Sp1 is involved in the recurrence of glioblastoma (GBM) due to the acquirement of resistance to temozolomide (TMZ). Particularly, the role of Sp1 in metabolic reprogramming for drug resistance remains unknown. Methods RNA-Seq and
Externí odkaz:
https://doaj.org/article/41e5eb2931d64c3ea1398dfe091319be
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundOblique lateral interbody fusion (OLIF) is a type of minimally invasive lateral lumbar interbody fusion technique used for treating lumbar degenerative diseases. This study aimed to analyze the clinical and radiographic efficacy of OLIF wit
Externí odkaz:
https://doaj.org/article/47360a0149f8494da22eead2ab791653
Autor:
Wen-Bin Yang, An-Chih Wu, Tsung-I Hsu, Jing-Ping Liou, Wei-Lun Lo, Kwang-Yu Chang, Pin-Yuan Chen, Ushio Kikkawa, Shung-Tai Yang, Tzu-Jen Kao, Ruei-Ming Chen, Wen-Chang Chang, Chiung-Yuan Ko, Jian-Ying Chuang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract DNA repair promotes the progression and recurrence of glioblastoma (GBM). However, there remain no effective therapies for targeting the DNA damage response and repair (DDR) pathway in the clinical setting. Thus, we aimed to conduct a compre
Externí odkaz:
https://doaj.org/article/0550dd11627c4cb1b510f29cabb3b452
Publikováno v:
Journal of Islamic Civilization, Vol 4, Iss 1 (2022)
Unification theory seeks to gain a comprehensive understanding of something. The goal of unification theory is to bring together multiviews on love. If “Love” is not understood from multiple perspectives, it will be difficult to understand and ea
Externí odkaz:
https://doaj.org/article/24d888de71c74d03bfbd8b37492283ad
Evidence of Long-range nerve pathways connecting and coordinating activity in secondary lymph organs
Autor:
Victoria Cotero, Tzu-Jen Kao, John Graf, Jeffrey Ashe, Christine Morton, Sangeeta S. Chavan, Stavros Zanos, Kevin J. Tracey, Christopher M. Puleo
Publikováno v:
Bioelectronic Medicine, Vol 6, Iss 1, Pp 1-14 (2020)
Abstract Background Peripheral nerve reflexes enable organ systems to maintain long-term physiological homeostasis while responding to rapidly changing environmental conditions. Electrical nerve stimulation is commonly used to activate these reflexes
Externí odkaz:
https://doaj.org/article/713cfed1d6a941f6a6b059f4d0ceadd2
Autor:
Man-Hau Ho, Chia-Hung Yen, Tsung-Hsun Hsieh, Tzu-Jen Kao, Jing-Yuan Chiu, Yung-Hsiao Chiang, Barry J. Hoffer, Wen-Chang Chang, Szu-Yi Chou
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102067- (2021)
Traumatic brain injury (TBI) is a prevalent head injury worldwide which increases the risk of neurodegenerative diseases. Increased reactive oxygen species (ROS) and inflammatory chemokines after TBI induces secondary effects which damage neurons. Ta
Externí odkaz:
https://doaj.org/article/91593b3bc5904dee8b942b464cbec397
Autor:
Shao-Ming Wang, Hong-Yi Lin, Yen-Lin Chen, Tsung-I Hsu, Jian-Ying Chuang, Tzu-Jen Kao, Chiung-Yuan Ko
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background The small population of glioma stem-like cells (GSCs) contributes to tumor initiation, malignancy, and recurrence in glioblastoma. However, the maintenance of GSC properties in the tumor microenvironment remains unclear. In glioma
Externí odkaz:
https://doaj.org/article/a18f117ea2824020ad47a4e7e861366d
Autor:
Hsin-Chuan Lin, Yung-Hao Ching, Chi-Chen Huang, Ping-Chieh Pao, Yi-Hua Lee, Wen-Chang Chang, Tzu-Jen Kao, Yi-Chao Lee
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Abstract Background Promyelocytic leukemia zinc finger (Plzf), a transcriptional regulator involved in a lot of important biological processes during development, has been implied to maintain neural stem cells and inhibit their differentiation into n
Externí odkaz:
https://doaj.org/article/9ae4e5a8016c47c3a8950a02088b3e76
Autor:
Victoria Cotero, Ying Fan, Tea Tsaava, Adam M. Kressel, Ileana Hancu, Paul Fitzgerald, Kirk Wallace, Sireesha Kaanumalle, John Graf, Wayne Rigby, Tzu-Jen Kao, Jeanette Roberts, Chitresh Bhushan, Suresh Joel, Thomas R. Coleman, Stavros Zanos, Kevin J. Tracey, Jeffrey Ashe, Sangeeta S. Chavan, Christopher Puleo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Stimulation of peripheral nerve activity may be used to treat metabolic and inflammatory disorders, but current approaches need implanted devices. Here, the authors present a non-invasive approach, and show that ultrasound-mediated stimulation can be
Externí odkaz:
https://doaj.org/article/77a64eba47a04d5e919deb62157049e8