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Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

Autor: Nishijima, Daniel K, VanBuren, John, Hewes, Hilary A, Myers, Sage R, Stanley, Rachel M, Adelson, P David, Barnhard, Sarah E, Bobinski, Matthew, Ghetti, Simona, Holmes, James F, Roberts, Ian, Schalick, Walton O, Tran, Nam K, Tzimenatos, Leah S, Michael Dean, J, Kuppermann, Nathan, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Re

Publikováno v: Trials, vol 19, iss 1
Trials
Trials, Vol 19, Iss 1, Pp 1-10 (2018)

Background Trauma is the leading cause of morbidity and mortality in children in the United States. The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage, however, the drug has not been evaluated in a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6862908fdd6cd396f7f7c98533fe14a
https://researchonline.lshtm.ac.uk/id/eprint/4649943/1/s13063-018-2974-z.pdf

Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial.

Autor: Nishijima DK; Department of Emergency Medicine, UC Davis School of Medicine, 4150 V. Street, PSSB 2100, Sacramento, CA, 95817, USA. dnishijima@ucdavis.edu., VanBuren J; Department of Pediatrics, University of Utah School of Medicine, 295 Chipeta Way, Salt Lake City, UT, 84108, USA., Hewes HA; Department of Pediatrics, Division of Pediatric Emergency Medicine, University of Utah School of Medicine, Primary Children's Hospital, 100 N. Mario Capecchi Dr., Salt Lake City, UT, 84113, USA., Myers SR; Department of Pediatrics, Division of Pediatric Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA., Stanley RM; Department of Pediatrics, Division of Pediatric Emergency Medicine, Ohio State University School of Medicine, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH, 43205, USA., Adelson PD; Department of Pediatric Neurosciences, Barrow Neurological Institute at Phoenix Children's Hospital, 1919 E. Thomas Rd, Phoenix, AZ, 85016, USA., Barnhard SE; Department of Pathology and Laboratory Medicine, UC Davis School of Medicine, 2315 Stockton Blvd., Sacramento, CA, 95817, USA., Bobinski M; Department of Radiology, UC Davis School of Medicine, 2315 Stockton Blvd., Sacramento, CA, 95817, USA., Ghetti S; Department of Psychology, University of California, Davis, 102K Young Hall, 1 Shields Ave., Davis, CA, 95616, USA., Holmes JF; Department of Emergency Medicine, UC Davis School of Medicine, 4150 V. Street, PSSB 2100, Sacramento, CA, 95817, USA., Roberts I; Department of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Schalick WO 3rd; Department of Orthopedics and Rehabilitation, University of Wisconsin, 317 Knutson Drive, Madison, WI, 53704, USA., Tran NK; Department of Pathology and Laboratory Medicine, University of California, Davis, 3422 Tupper Hall, Davis, CA, 95616, USA., Tzimenatos LS; Department of Emergency Medicine, UC Davis School of Medicine, 4150 V. Street, PSSB 2100, Sacramento, CA, 95817, USA., Michael Dean J; Department of Pediatrics, University of Utah School of Medicine, 295 Chipeta Way, Salt Lake City, UT, 84108, USA., Kuppermann N; Departments of Emergency Medicine and Pediatrics, UC Davis School of Medicine, 4150 V. Street, PSSB 2100, Sacramento, CA, 95817, USA.

Publikováno v: Trials [Trials] 2018 Oct 30; Vol. 19 (1), pp. 593. Date of Electronic Publication: 2018 Oct 30.