Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Tze Sian Chan"'
Autor:
Sohyun Jeong, Yi-Tyng Liao, Min-Hsuan Tsai, Yao-Kuang Wang, I-Chen Wu, Chung-Jung Liu, Ming-Shun Wu, Tze-Sian Chan, Ming-Yao Chen, Ping-Jen Hu, Wei-Yu Kao, Hsiang-Chin Liu, Ming-Ju Tsai, Cheng-Yuan Liu, Chun-Chao Chang, Deng-Chyang Wu, Yi-Hsiang Hsu
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Gastric cancer is one of the global health concerns. A series of studies on the stomach have confirmed the role of the microbiome in shaping gastrointestinal diseases. Delineation of microbiome signatures to distinguish chronic ga
Externí odkaz:
https://doaj.org/article/c315a93a608341eb847bb39eb1d51949
Autor:
Tze‐Sian Chan, Li‐Hsin Cheng, Chung‐Chi Hsu, Pei‐Ming Yang, Tai‐Yan Liao, Hsiao‐Yen Hsieh, Pei‐Chun Lin, Wei‐Chun HuangFu, Chih‐Pin Chuu, Kelvin K. Tsai
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 562-579 (2024)
Notch signaling is aberrantly activated in approximately 30% of hepatocellular carcinoma (HCC), significantly contributing to tumorigenesis and disease progression. Expression of the major Notch receptor, NOTCH1, is upregulated in HCC cells and corre
Externí odkaz:
https://doaj.org/article/98d41b996f2a46b5a4a99daf235a8532
Autor:
Tze Sian Chan, 張智翔
98
Background: The stromal microenvironments in which tumors develop profoundly influence many steps of epithelial tumorigenesis. Pancreatic stellate cells (PaSCs) are the major contributors of the desmoplastic stromal microenvironment of pancre
Background: The stromal microenvironments in which tumors develop profoundly influence many steps of epithelial tumorigenesis. Pancreatic stellate cells (PaSCs) are the major contributors of the desmoplastic stromal microenvironment of pancre
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/tzk859
Autor:
Wen-Ying Liao, Chung-Chi Hsu, Tze-Sian Chan, Chia-Jui Yen, Wei-Yu Chen, Hung-Wei Pan, Kelvin K. Tsai
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 462-477 (2020)
Summary: Various populations of cancer stem cells (CSCs) have been identified in hepatocellular carcinoma (HCC). Wnt signaling is variably activated in HCC and regulates CSCs and tumorigenesis. We explored cell-to-cell Wnt and stemness heterogeneity
Externí odkaz:
https://doaj.org/article/1424c1640622477d9db3d11114a2ae15
Autor:
Shenq-Shyang Huang, Wen-Ying Liao, Chung-Chi Hsu, Tze-Sian Chan, Tai-Yan Liao, Pei-Ming Yang, Li-Tzong Chen, Shian-Ying Sung, Kelvin K. Tsai
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/0ee3b4985b4a406db566d707f284a2bc
Autor:
Shenq-Shyang Huang, Wen-Ying Liao, Chung-Chi Hsu, Tze-Sian Chan, Tai-Yan Liao, Pei-Ming Yang, Li-Tzong Chen, Shian-Ying Sung, Kelvin K. Tsai
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionStem-like cancer cells or cancer stem cells (CSCs) may comprise a phenotypically and functionally heterogeneous subset of cells, whereas the molecular markers reflecting this CSC hierarchy remain elusive. The glycolytic enzyme alpha-enola
Externí odkaz:
https://doaj.org/article/fe1df7fbf0ab4bdf93b90ac6b446789c
ASPM Activates Hedgehog and Wnt Signaling to Promote Small Cell Lung Cancer Stemness and Progression
Autor:
Li-Hsin Cheng, Chung-Chi Hsu, Hung-Wen Tsai, Wen-Ying Liao, Pei-Ming Yang, Tai-Yan Liao, Hsiao-Yen Hsieh, Tze-Sian Chan, Kelvin K. Tsai
Publikováno v:
Cancer Research. 83:830-844
Small cell lung cancer (SCLC) is among the most aggressive and lethal human malignancies. Most patients with SCLC who initially respond to chemotherapy develop disease relapse. Therefore, there is a pressing need to identify novel driver mechanisms o
Publikováno v:
Journal of Cancer Research and Practice, Vol 4, Iss 4, Pp 123-126 (2017)
Metronomic chemotherapy involves the administration of cytotoxic chemotherapy at reduced doses administered at regular and frequent intervals. Low-dose metronomic (LDM) chemotherapy represents an alternative to standard maximum tolerated dose (MTD) c
Externí odkaz:
https://doaj.org/article/5354c0492e0e4c9db4bf229462b90932
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Malignant tumors are highly heterogeneous and likely contain a subset of cancer cells termed cancer stem cells (CSCs). CSCs exist in a dynamic equilibrium with their microenvironments and the CSC phenotype is tightly regulated by both cell-intrinsic
Externí odkaz:
https://doaj.org/article/8e20fad693964d089134f45ac81156f1
Autor:
Fat-Moon Suk, Chi-Ching Chang, Pei-Chi Sun, Wei-Ting Ke, Chia-Chen Chung, Kun-Lin Lee, Tze-Sian Chan, Yu-Chih Liang
Publikováno v:
Biology, Vol 10, Iss 7, p 655 (2021)
Monocyte chemoattractant protein-1-induced protein 1 (MCPIP1) is rapidly produced under proinflammatory stimuli, thereby feeding back to downregulate excessive inflammation. In this study, we used the stable, inducible expressions of wild-type (WT) M
Externí odkaz:
https://doaj.org/article/e50c4389947845fead94ba5e4497715a