Výsledky vyhledávání - "Tzamakou, E."

Feasibility study and pharmacokinetics of low-dose paclitaxel in cancer patients with severe hepatic dysfunction

Autor: Briassoulis, E. Ch, Karavasilis, V., Tzamakou, E., Piperidou, C., Soulti, K., Pavlidis, Nicholas

Publikováno v: Anti-Cancer Drugs

The aim of this study is to investigate the feasibility and determine the pharmacokinetics of low-dose paclitaxel in cancer patients with severe hepatic dysfunction. This was a prospective study. Patients with liver metastases who had either transami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b704748d5292c8bd9ff688d7e479ce82
https://doi.org/10.1097/01.cad.0000236301.12715.6b

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Phase I Trial of Intravenous Cisplatin-Topotecan Chemotherapy for Three Consecutive Days in Patients with Advanced Solid Tumors: Parallel Topotecan Escalation in Two Fixed Platinum Dosing Schemes

Autor: Pentheroudakis, George, Briassoulis, E. Ch, Karavasilis, V., Mauri, D., Tzamakou, E., Rammou, D., Pavlidis, Nicholas

Publikováno v: Chemotherapy

Purpose: We performed a phase I study of two fixed dosing schemes of cisplatin, a DNA cross-linker, with intravenous escalating topotecan, a DNA-topoisomerase I inhibitor. Experimental Design: 40 patients with advanced solid tumors received intraveno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b8ddeed875ed278e4d4bad707d9eee
https://doi.org/10.1159/000085624

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Interaction pharmacokinetics of pegylated liposomal doxorubicin (Caelyx) on coadministration with paclitaxel or docetaxel

Autor: Briassoulis, E. Ch, Karavasilis, V., Tzamakou, E., Rammou, D., Soulti, K., Piperidou, C., Pavlidis, Nicholas

Publikováno v: Cancer chemotherapy and pharmacology

Purpose: To investigate the pharmacokinetics of polyethylene glycol-coated liposomal doxorubicin (PLD, Caelyx) when given as a single agent and in combination with the taxanes paclitaxel or docetaxel in humans. Methods: The plasma kinetics of PLD wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf8c01027ddb6014512733cf709d3b2
https://doi.org/10.1007/s00280-003-0750-5

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Weekday on-weekend off oral capecitabine: a phase I study of a continuous schedule better simulating protracted fluoropyrimidine therapy

Autor: Pentheroudakis, George, Pappas, P., Golfinopoulos, Vassilis, Fountzilas, George, Nikolaidou, M., Boumba, V. A., Vougiouklakis, T., Nikiforidis, L., Tzamakou, E., Siarabi, O., Marselos, M., Pavlidis, Nicholas

Publikováno v: Cancer chemotherapy and pharmacology

Background: Although protracted intravenous 5-fluorouracil is superior to bolus regimens in terms of tumour exposure to the drug during DNA synthesis as well as activity and safety, the oral fluoropyrimidine capecitabine is administered intermittentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d992c1ec3d3408cd1bf11e9ca8d8c0c3
https://pubmed.ncbi.nlm.nih.gov/17333194

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Weekly paclitaxel combined with pegylated liposomal doxorubicin (Caelyx ™) given every 4 weeks: Dose-finding and pharmacokinetic study in patients with advanced solid tumors

Autor: Briassoulis, E. Ch, Pentheroudakis, George, Karavasilis, V., Tzamakou, E., Rammou, D., Pavlidis, Nicholas

Publikováno v: Annals of Oncology

Background: We aimed to define the maximum tolerated dose (MTD) and characterize the toxicity of the combination of pegylated liposomal doxorubicin (PLD; Caelyx™) and weekly paclitaxel (wPTX), and to investigate pharmacokinetics of PLD in this comb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c404139242d04d0d60ef76f0b2abeb2
https://gnosis.library.ucy.ac.cy/handle/7/41419

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