Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tyzoon Nomanbhoy"'
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172649 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0152934.].
Externí odkaz:
https://doaj.org/article/a8fee0abbac8433b9e3e6fd4953734b3
Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152934 (2016)
We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics. Matched normal and tumor colon samples were analyzed using an ATP acyl phosphate probe in a
Externí odkaz:
https://doaj.org/article/ffc6200c89354154984d306f8d950e36
Autor:
Zoë Johnson, Chiara Tarantelli, Elisa Civanelli, Luciano Cascione, Filippo Spriano, Amy Fraser, Pritom Shah, Tyzoon Nomanbhoy, Sara Napoli, Andrea Rinaldi, Karolina Niewola-Staszkowska, Michael Lahn, Dominique Perrin, Mathias Wenes, Denis Migliorini, Francesco Bertoni, Lars van der Veen, Giusy Di Conza
Publikováno v:
Cancer Research Communications. 3:576-591
PI3K delta (PI3Kδ) inhibitors are used to treat lymphomas but safety concerns and limited target selectivity curbed their clinical usefulness. PI3Kδ inhibition in solid tumors has recently emerged as a potential novel anticancer therapy through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18c36b665c5298e1e41acbc88ccc5d68
https://doi.org/10.1158/2767-9764.crc-22-0477
https://doi.org/10.1158/2767-9764.crc-22-0477
Publikováno v:
Autophagy. :1-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c17e3bb75ebf54211d9795580e353d
https://doi.org/10.1080/15548627.2023.2182594
https://doi.org/10.1080/15548627.2023.2182594
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
Target engagement kinase tree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e48f330c4be9c625cf4c94237f10cc
https://doi.org/10.1158/2767-9764.22634434
https://doi.org/10.1158/2767-9764.22634434
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
Table summarizing the IC50 values derived from previous published experiments performed with IOA-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6859857a49b6c3e892790e8a544721ec
https://doi.org/10.1158/2767-9764.22634425.v1
https://doi.org/10.1158/2767-9764.22634425.v1
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
PI3K delta (PI3Kδ) inhibitors are used to treat lymphomas but safety concerns and limited target selectivity curbed their clinical usefulness. PI3Kδ inhibition in solid tumors has recently emerged as a potential novel anticancer therapy through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4902879218007350c0bf6163104f3caa
https://doi.org/10.1158/2767-9764.c.6551246
https://doi.org/10.1158/2767-9764.c.6551246
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
Correlation analysis of PI3Kd levels and the response to IOA-244 and Idelalisib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff549e13245e67d824071968b3d33de
https://doi.org/10.1158/2767-9764.22546793
https://doi.org/10.1158/2767-9764.22546793
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
Phosphoinositide 3-kinase delta (PI3Kd) inhibitors are used to treat lymphomas but safety concerns and limited target selectivity curbed their clinical usefulness. PI3Kd inhibition in solid tumors has recently emerged as a potential novel anti-cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1aeb158052be023ce9ba699df9885fc
https://doi.org/10.1158/2767-9764.c.6551246.v1
https://doi.org/10.1158/2767-9764.c.6551246.v1
Autor:
Giusy Di Conza, Lars van der Veen, Francesco Bertoni, Denis Migliorini, Mathias Wenes, Dominique Perrin, Michael Lahn, Karolina Niewola-Staszkowska, Andrea Rinaldi, Sara Napoli, Tyzoon Nomanbhoy, Pritom Shah, Amy Fraser, Filippo Spriano, Luciano Cascione, Elisa Civanelli, Chiara Tarantelli, Zoë Johnson
Table showing values of microsomal stability of IOA-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64384f01720202ebaa03bea24446e0e7
https://doi.org/10.1158/2767-9764.22546784
https://doi.org/10.1158/2767-9764.22546784