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pro vyhledávání: '"Tyson Dawson"'
Autor:
Tyson Dawson, Uzma Rentia, Jessie Sanford, Carlos Cruchaga, John S. K. Kauwe, Keith A. Crandall
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionHuman endogenous retroviruses (HERVs) are transcriptionally-active remnants of ancient retroviral infections that may play a role in Alzheimer’s disease.MethodsWe combined two, publicly available RNA-Seq datasets with a third, novel dat
Externí odkaz:
https://doaj.org/article/1852eb2d44514d08ae2e4b85e874498f
Autor:
Ali Rahnavard, Tyson Dawson, Rebecca Clement, Nathaniel Stearrett, Marcos Pérez-Losada, Keith A. Crandall
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract SARS-CoV-2 (CoV) is the etiological agent of the COVID-19 pandemic and evolves to evade both host immune systems and intervention strategies. We divided the CoV genome into 29 constituent regions and applied novel analytical approaches to id
Externí odkaz:
https://doaj.org/article/f38b7a7ac21d46d6bbf4eef2b9aa3065
Autor:
Jessica-Miranda Bustamante, Tyson Dawson, Caitlin Loeffler, Zara Marfori, Julian R. Marchesi, Benjamin H. Mullish, Christopher C. Thompson, Keith A. Crandall, Ali Rahnavard, Jessica R. Allegretti, Bethany P. Cummings
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5200 (2022)
Fecal microbiota transplantation (FMT) is a promising therapeutic modality for the treatment and prevention of metabolic disease. We previously conducted a double-blind, randomized, placebo-controlled pilot trial of FMT in obese metabolically healthy
Externí odkaz:
https://doaj.org/article/9d84f6087c4d4da2ac0bd7c675b65565
Autor:
Nathaniel Stearrett, Tyson Dawson, Ali Rahnavard, Prathyusha Bachali, Matthew L. Bendall, Chen Zeng, Roberto Caricchio, Marcos Pérez-Losada, Amrie C. Grammer, Peter E. Lipsky, Keith A. Crandall
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies predominantly to nuclear material. Many aspects of disease pathology are mediated by the deposition of nucleic acid containing immune
Externí odkaz:
https://doaj.org/article/1764a61a79264ac2944a875bd12c909c
deepBreaks: a Machine Learning Tool for Identifying and Prioritizing Genotype-phenotype Associations
Sequence data (e.g., nucleotides or amino-acids) are critical for advancing our understanding of biology. However, there are many challenges with investigating and analyzing sequencing data and genotype-phenotype associations, including non-independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f89c7ea9c7081668f40dde8d0999bec1
https://doi.org/10.21203/rs.3.rs-2534899/v1
https://doi.org/10.21203/rs.3.rs-2534899/v1
Autor:
Jijun Yu, Wubing Zhang, Zexiang Zeng, Yuan Gao, Xiaolong Cheng, Yingbo Cui, Tyson Dawson, Shaoliang Peng, Wei Li, Bicna Song, Lumen Chao, Teng Fei, Dian Li, Qing Chen, Anthony Chiu, Zexu Li
Publikováno v:
Nucleic Acids Research
High-throughput genetic screening based on CRISPR/Cas9 or RNA-interference (RNAi) enables the exploration of genes associated with the phenotype of interest on a large scale. The rapid accumulation of public available genetic screening data provides
Autor:
Elodie Billet, Jennifer Arce, Kevin Ekins, Jess Gann, Joel Manwaring, Tyson Dawson, Nick A Francis, Briana Flaherty, Caroline Dubost, Harmonie Durand, Laurence Barbier, Christopher A. Cantrell, Elizabeth Amiott, Josh Southwick
Publikováno v:
Open Forum Infectious Diseases
Background The BioFire Bone and Joint Infection (BJI) Panel is a sample-to-answer test for the qualitative detection of nearly 40 different bacteria, yeast, and antimicrobial resistance (AMR) genes in synovial fluid (SF). The panel aims to improve on