Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Tyson A. Clark"'
Autor:
Jeremy M. Foster, Alexandra Grote, John Mattick, Alan Tracey, Yu-Chih Tsai, Matthew Chung, James A. Cotton, Tyson A. Clark, Adam Geber, Nancy Holroyd, Jonas Korlach, Yichao Li, Silvia Libro, Sara Lustigman, Michelle L. Michalski, Michael Paulini, Matthew B. Rogers, Laura Teigen, Alan Twaddle, Lonnie Welch, Matthew Berriman, Julie C. Dunning Hotopp, Elodie Ghedin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome evol
Externí odkaz:
https://doaj.org/article/ea0bdea21b12449787ed0d4781e26b36
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Fragmentation of transcripts can hide operon complexity in genome-wide transcriptome sequencing. Here the authors sequenced a prokaryotic transcriptome using PacBio and provide insights into operon structure and read-through at termination sites.
Externí odkaz:
https://doaj.org/article/95f6d441d26240938f4bffd16b2807b2
Autor:
Alexandra L. Bryson, Young Hwang, Scott Sherrill-Mix, Gary D. Wu, James D. Lewis, Lindsay Black, Tyson A. Clark, Frederic D. Bushman
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT The genomic DNAs of tailed bacteriophages are commonly modified by the attachment of chemical groups. Some forms of DNA modification are known to protect phage DNA from cleavage by restriction enzymes, but others are of unknown function. Rec
Externí odkaz:
https://doaj.org/article/2d549af73f85431d9cd2431ee86d1e36
Autor:
Rory A. Eutsey, Evan Powell, Janina Dordel, Susannah J. Salter, Tyson A. Clark, Jonas Korlach, Garth D. Ehrlich, N. Luisa Hiller
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT The human pathogen Streptococcus pneumoniae (pneumococcus) exhibits a high degree of genomic diversity and plasticity. Isolates with high genomic similarity are grouped into lineages that undergo homologous recombination at variable rates. P
Externí odkaz:
https://doaj.org/article/8efb1484f36b4fb2aeee87b5b10d03d3
Autor:
Joe W. Gray, John Conboy, Paul Spellman, Heidi Feiler, Andrew Wyrobek, Anthony Schweitzer, Tyson A. Clark, Shannon Dorton, Hovig Bayandorian, Martha Stampfer, James Garbe, Terence Speed, Gerald Fontenay, Bahram Parvin, Nicholas Wang, Steffen Durinck, Lior Pachter, Ken Simpson, Zhi Hu, Elizabeth Purdom, Sanchita Bhattacharya, Helder Pedro, Lakshmi Jakkula, Henry Marr, Anna Lapuk
Protein isoforms produced by alternative splicing (AS) of many genes have been implicated in several aspects of cancer genesis and progression. These observations motivated a genome-wide assessment of AS in breast cancer. We accomplished this by meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d3252c7b8f7691ff73c769c310e1a
https://doi.org/10.1158/1541-7786.c.6541929
https://doi.org/10.1158/1541-7786.c.6541929
Autor:
Joe W. Gray, John Conboy, Paul Spellman, Heidi Feiler, Andrew Wyrobek, Anthony Schweitzer, Tyson A. Clark, Shannon Dorton, Hovig Bayandorian, Martha Stampfer, James Garbe, Terence Speed, Gerald Fontenay, Bahram Parvin, Nicholas Wang, Steffen Durinck, Lior Pachter, Ken Simpson, Zhi Hu, Elizabeth Purdom, Sanchita Bhattacharya, Helder Pedro, Lakshmi Jakkula, Henry Marr, Anna Lapuk
Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306d9d8902f9da481360f461c72f61c6
https://doi.org/10.1158/1541-7786.22518468.v1
https://doi.org/10.1158/1541-7786.22518468.v1
Autor:
Joe W. Gray, John Conboy, Paul Spellman, Heidi Feiler, Andrew Wyrobek, Anthony Schweitzer, Tyson A. Clark, Shannon Dorton, Hovig Bayandorian, Martha Stampfer, James Garbe, Terence Speed, Gerald Fontenay, Bahram Parvin, Nicholas Wang, Steffen Durinck, Lior Pachter, Ken Simpson, Zhi Hu, Elizabeth Purdom, Sanchita Bhattacharya, Helder Pedro, Lakshmi Jakkula, Henry Marr, Anna Lapuk
Supplementary Figures S1-S2 and Supplementary Tables S2-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c69c570d1adc9997c1e3621254df6a7
https://doi.org/10.1158/1541-7786.22518471
https://doi.org/10.1158/1541-7786.22518471
Autor:
Matthew J Blow, Tyson A Clark, Chris G Daum, Adam M Deutschbauer, Alexey Fomenkov, Roxanne Fries, Jeff Froula, Dongwan D Kang, Rex R Malmstrom, Richard D Morgan, Janos Posfai, Kanwar Singh, Axel Visel, Kelly Wetmore, Zhiying Zhao, Edward M Rubin, Jonas Korlach, Len A Pennacchio, Richard J Roberts
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005854 (2016)
DNA methylation acts in concert with restriction enzymes to protect the integrity of prokaryotic genomes. Studies in a limited number of organisms suggest that methylation also contributes to prokaryotic genome regulation, but the prevalence and prop
Externí odkaz:
https://doaj.org/article/611a8e3186b0460990c4d6a70850c22d
Autor:
Cary Pirone-Davies, Maria Hoffmann, Richard J Roberts, Tim Muruvanda, Ruth E Timme, Errol Strain, Yan Luo, Justin Payne, Khai Luong, Yi Song, Yu-Chih Tsai, Matthew Boitano, Tyson A Clark, Jonas Korlach, Peter S Evans, Marc W Allard
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123639 (2015)
The methylation of DNA bases plays an important role in numerous biological processes including development, gene expression, and DNA replication. Salmonella is an important foodborne pathogen, and methylation in Salmonella is implicated in virulence
Externí odkaz:
https://doaj.org/article/04dca1afa2eb4085b825d589e0a3e1f3
Autor:
Mohamad R Abdul Sater, Araceli Lamelas, Guilin Wang, Tyson A Clark, Katharina Röltgen, Shrikant Mane, Jonas Korlach, Gerd Pluschke, Christoph D Schmid
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144612 (2015)
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable colon
Externí odkaz:
https://doaj.org/article/897120430ec34366ae98e7ec69811d1b