Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Tyson A Clark"'
Autor:
Iain A Murray, Yvette A Luyten, Alexey Fomenkov, Nan Dai, Ivan R Corrêa, William G Farmerie, Tyson A Clark, Jonas Korlach, Richard D Morgan, Richard J Roberts
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253267 (2021)
We report a new subgroup of Type III Restriction-Modification systems that use m4C methylation for host protection. Recognition specificities for six such systems, each recognizing a novel motif, have been determined using single molecule real-time D
Externí odkaz:
https://doaj.org/article/2f77b6fdc04f4e65b94bfac091b7ee0f
Autor:
Bo Wang, Elizabeth Tseng, Michael Regulski, Tyson A Clark, Ting Hon, Yinping Jiao, Zhenyuan Lu, Andrew Olson, Joshua C. Stein, Doreen Ware
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zea mays is an important crop species and genetic model but uncertainties remain regarding the structure of the transcriptome. Here Wang et al. use single-molecule sequencing and size-fractionated libraries to identify novel transcripts and isoforms
Externí odkaz:
https://doaj.org/article/32d3e91deb6449e6b10801c5ae9e69ba
Autor:
Matthew J Blow, Tyson A Clark, Chris G Daum, Adam M Deutschbauer, Alexey Fomenkov, Roxanne Fries, Jeff Froula, Dongwan D Kang, Rex R Malmstrom, Richard D Morgan, Janos Posfai, Kanwar Singh, Axel Visel, Kelly Wetmore, Zhiying Zhao, Edward M Rubin, Jonas Korlach, Len A Pennacchio, Richard J Roberts
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005854 (2016)
DNA methylation acts in concert with restriction enzymes to protect the integrity of prokaryotic genomes. Studies in a limited number of organisms suggest that methylation also contributes to prokaryotic genome regulation, but the prevalence and prop
Externí odkaz:
https://doaj.org/article/611a8e3186b0460990c4d6a70850c22d
Autor:
Cary Pirone-Davies, Maria Hoffmann, Richard J Roberts, Tim Muruvanda, Ruth E Timme, Errol Strain, Yan Luo, Justin Payne, Khai Luong, Yi Song, Yu-Chih Tsai, Matthew Boitano, Tyson A Clark, Jonas Korlach, Peter S Evans, Marc W Allard
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123639 (2015)
The methylation of DNA bases plays an important role in numerous biological processes including development, gene expression, and DNA replication. Salmonella is an important foodborne pathogen, and methylation in Salmonella is implicated in virulence
Externí odkaz:
https://doaj.org/article/04dca1afa2eb4085b825d589e0a3e1f3
Autor:
Mohamad R Abdul Sater, Araceli Lamelas, Guilin Wang, Tyson A Clark, Katharina Röltgen, Shrikant Mane, Jonas Korlach, Gerd Pluschke, Christoph D Schmid
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144612 (2015)
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable colon
Externí odkaz:
https://doaj.org/article/897120430ec34366ae98e7ec69811d1b
Autor:
Mary O' Connell Motherway, Debbie Watson, Francesca Bottacini, Tyson A Clark, Richard J Roberts, Jonas Korlach, Peggy Garault, Christian Chervaux, Johan E T van Hylckama Vlieg, Tamara Smokvina, Douwe van Sinderen
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94875 (2014)
Bifidobacterium animalis subsp. lactis CNCM I-2494 is a component of a commercialized fermented dairy product for which beneficial effects on health has been studied by clinical and preclinical trials. To date little is known about the molecular mech
Externí odkaz:
https://doaj.org/article/45c98f8593924a5c8a4fa5eeb92c45ac
Autor:
Maria Lluch-Senar, Khai Luong, Verónica Lloréns-Rico, Javier Delgado, Gang Fang, Kristi Spittle, Tyson A Clark, Eric Schadt, Stephen W Turner, Jonas Korlach, Luis Serrano
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003191 (2013)
In the bacterial world, methylation is most commonly associated with restriction-modification systems that provide a defense mechanism against invading foreign genomes. In addition, it is known that methylation plays functionally important roles, inc
Externí odkaz:
https://doaj.org/article/fd2db5da25724ff89f07a87e07500fb6
Autor:
Charles W Sugnet, Karpagam Srinivasan, Tyson A Clark, Georgeann O'Brien, Melissa S Cline, Hui Wang, Alan Williams, David Kulp, John E Blume, David Haussler, Manuel Ares
Publikováno v:
PLoS Computational Biology, Vol 2, Iss 1, p e4 (2006)
Alternative splicing contributes to both gene regulation and protein diversity. To discover broad relationships between regulation of alternative splicing and sequence conservation, we applied a systems approach, using oligonucleotide microarrays des
Externí odkaz:
https://doaj.org/article/8f0a472f344c4f99967c413a01ca32ef
Autor:
Joe W. Gray, John Conboy, Paul Spellman, Heidi Feiler, Andrew Wyrobek, Anthony Schweitzer, Tyson A. Clark, Shannon Dorton, Hovig Bayandorian, Martha Stampfer, James Garbe, Terence Speed, Gerald Fontenay, Bahram Parvin, Nicholas Wang, Steffen Durinck, Lior Pachter, Ken Simpson, Zhi Hu, Elizabeth Purdom, Sanchita Bhattacharya, Helder Pedro, Lakshmi Jakkula, Henry Marr, Anna Lapuk
Protein isoforms produced by alternative splicing (AS) of many genes have been implicated in several aspects of cancer genesis and progression. These observations motivated a genome-wide assessment of AS in breast cancer. We accomplished this by meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d3252c7b8f7691ff73c769c310e1a
https://doi.org/10.1158/1541-7786.c.6541929
https://doi.org/10.1158/1541-7786.c.6541929
Autor:
Joe W. Gray, John Conboy, Paul Spellman, Heidi Feiler, Andrew Wyrobek, Anthony Schweitzer, Tyson A. Clark, Shannon Dorton, Hovig Bayandorian, Martha Stampfer, James Garbe, Terence Speed, Gerald Fontenay, Bahram Parvin, Nicholas Wang, Steffen Durinck, Lior Pachter, Ken Simpson, Zhi Hu, Elizabeth Purdom, Sanchita Bhattacharya, Helder Pedro, Lakshmi Jakkula, Henry Marr, Anna Lapuk
Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306d9d8902f9da481360f461c72f61c6
https://doi.org/10.1158/1541-7786.22518468.v1
https://doi.org/10.1158/1541-7786.22518468.v1