The fragmented COVID-19 therapeutics research landscape: a living systematic review of clinical trial registrations evaluating priority pharmacological interventions. [version 1; peer review: 1 approved]

Autor: McLean, ARD, Rashan, S, Tran, L, Arena, L, Lawal, A, Maguire, BJ, Adele, S, Antonio, ES, Brack, M, Caldwell, F, Carrara, VI, Charles, R, Citarella, BW, Epie, TB, Feteh, VF, Kennon, K, Makuka, GJ, Ngu, R, Nwosu, A-P, Obiesie, S, Ogbonnaa-Njoku, C, Paul, P, Richmond, C, Singh-Phulgenda, S, Strudwick, S, Tyrrell, CSB, Stepniewska, K, Strub-Wourgaft, N, White, NJ, Guérin, PJ

Background: Many available medicines have been evaluated as potential repurposed treatments for coronavirus disease 2019 (COVID-19). We summarise the registered study landscape for 32 priority pharmacological treatments identified following consultat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::dd1b4ca42d0d480722c13481f82cdb97
http://hdl.handle.net/10044/1/104412

Engagement With mHealth COVID-19 Digital Biomarker Measurements in a Longitudinal Cohort Study: Mixed Methods Evaluation.

Autor: Rennie KL; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Lawlor ER; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Yassaee A; Huma Therapeutics Limited, London, United Kingdom., Booth A; Huma Therapeutics Limited, London, United Kingdom., Westgate K; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Sharp SJ; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Tyrrell CSB; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Aral M; Huma Therapeutics Limited, London, United Kingdom., Wareham NJ; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: Journal of medical Internet research [J Med Internet Res] 2023 Jan 13; Vol. 25, pp. e40602. Date of Electronic Publication: 2023 Jan 13.

Antimicrobial resistance in commensal opportunistic pathogens isolated from non-sterile sites can be an effective proxy for surveillance in bloodstream infections.

Autor: Vihta KD; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. karina-doris.vihta@eng.ox.ac.uk.; National Institute for Health Research Health Protection Research Unit, Oxford, UK. karina-doris.vihta@eng.ox.ac.uk.; Microbiology Research Level 7, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. karina-doris.vihta@eng.ox.ac.uk., Gordon NC; London School of Hygiene and Tropical Medicine, London, UK., Stoesser N; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Health Protection Research Unit, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Quan TP; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Health Protection Research Unit, Oxford, UK., Tyrrell CSB; University of Cambridge, Cambridge, UK., Vongsouvath M; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Laos., Ashley EA; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Laos.; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chansamouth V; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Laos.; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Turner P; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia., Ling CL; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand., Eyre DW; National Institute for Health Research Health Protection Research Unit, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Big Data Institute, University of Oxford, Oxford, UK., White NJ; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Crook D; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Health Protection Research Unit, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Peto TEA; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Health Protection Research Unit, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Walker AS; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Health Protection Research Unit, Oxford, UK.

Publikováno v: Scientific reports [Sci Rep] 2021 Dec 03; Vol. 11 (1), pp. 23359. Date of Electronic Publication: 2021 Dec 03.

Baseline results of a living systematic review for COVID-19 clinical trial registrations.

Autor: Maguire BJ; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., McLean ARD; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Rashan S; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Antonio ES; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bagaria J; Infectious Diseases Data Observatory (IDDO), Oxford, UK., Bentounsi Z; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Brack M; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Caldwell F; Infectious Diseases Data Observatory (IDDO), Oxford, UK., Carrara VI; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Shoklo Malaria Research Unit, Mahidol-Oxford University Research Unit, Mahidol University, Mae Sot, Tak, Thailand.; Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Citarella BW; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Dahal P; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Feteh VF; Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK.; Health and Human Development (2HD) Research Network, Douala, Cameroon., H B Guérin M; Infectious Diseases Data Observatory (IDDO), Oxford, UK., Kennon K; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bilton Lahaut K; Faculty of Medicine, University of Oslo, Oslo, Norway., Makuka GJ; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Ngu R; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Obiesie S; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Richmond C; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Singh-Phulgenda S; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Strudwick S; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tyrrell CSB; Public Health England, London, UK.; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Schwinn A; Exaptive, Inc., Oklahoma City, Oklahoma, USA., King D; Exaptive, Inc., Oklahoma City, Oklahoma, USA., Newton PN; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Lao-Oxford-Mahosot Hospital-Wellcome Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People's Democratic Republic., Price RN; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Merson L; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC), Oxford, UK., Stepniewska K; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Guérin PJ; Infectious Diseases Data Observatory (IDDO), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Publikováno v: Wellcome open research [Wellcome Open Res] 2020 Jun 02; Vol. 5, pp. 116. Date of Electronic Publication: 2020 Jun 02 (Print Publication: 2020).