Zobrazeno 1 - 10
of 2 399
pro vyhledávání: '"Tyrosine kinase receptor"'
Publikováno v:
Zhenduanxue lilun yu shijian, Vol 23, Iss 01, Pp 90-95 (2024)
Sepsis and concomitant multiorgan dysfunction are a group of common clinical syndromes, and their prevalence are increasing year by year due to the increase of the aging population. It reveals that 20 million cases of sepsis occur globally every year
Externí odkaz:
https://doaj.org/article/3a50c85bc0ef4101853b763b68b1b233
Autor:
Marie Fernandes, Brynna Hoggard, Philippe Jamme, Sonia Paget, Marie‐José Truong, Valérie Grégoire, Audrey Vinchent, Clotilde Descarpentries, Angela Morabito, Justas Stanislovas, Enoir Farage, Jean‐Pascal Meneboo, Shéhérazade Sebda, Katia Bouchekioua‐Bouzaghou, Marie Nollet, Sarah Humez, Timothy Perera, Paul Fromme, Luca Grumolato, Martin Figeac, Marie‐Christine Copin, David Tulasne, Alexis B. Cortot, Stéphanie Kermorgant, Zoulika Kherrouche
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2257-2274 (2023)
Exon skipping mutations of the MET receptor tyrosine kinase (METex14), increasingly reported in cancers, occur in 3–4% of non–small‐cell lung cancer (NSCLC). Only 50% of patients have a beneficial response to treatment with MET‐tyrosine kinas
Externí odkaz:
https://doaj.org/article/272f451e35f5414da2913aa27cf75f12
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 1981-1999 (2023)
Human epidermal growth factor receptor 2 (ErbB2/HER2) is a tyrosine kinase receptor that is overexpressed in 25% of primary human breast cancers, as well as in multiple other cancers. HER2‐targeted therapies improved progression‐free and overall
Externí odkaz:
https://doaj.org/article/0691d3b6eea04e3eb4db77f87a39729b
Autor:
Anna Qin, Yuan Qin, Joseph Lee, Anna Musket, Mingyao Ying, Giedre Krenciute, Francesco M. Marincola, Zhi Q. Yao, Phillip R. Musich, Qian Xie
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Recent progress in cancer immunotherapy encourages the expansion of chimeric antigen receptor (CAR) T cell therapy in solid tumors including hepatocellular carcinoma (HCC). Overexpression of MET receptor tyrosine kinase is common
Externí odkaz:
https://doaj.org/article/c7814fd1c0f24ba28819f129766ab27f
Autor:
Yang Yiqi, Zhang Bihui, Xie Junye, Li Jingsheng, Liu Jia, Liu Rongzhan, Zhang Linhao, Zhang Jinting, Su Zijian, Li Fu, Zhang Leisheng, Hong An, Chen Xiaojia
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1630-1639 (2023)
Umbilical cord blood (UCB) is an advantageous source for hematopoietic stem/progenitor cell (HSPC) transplantation, yet the current strategies for large-scale and cost-effective UCB-HSPC preparation are still unavailable. To overcome these obstacles,
Externí odkaz:
https://doaj.org/article/303797b9f96f438c85322a08327af74a
Autor:
Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this s
Externí odkaz:
https://doaj.org/article/7b18e3c4ca0f4f3fa01b364e3c354996
Autor:
Bo Mi Ku, Sungwon Park, Sehhoon Park, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Yoon-La Choi, Myung-Ju Ahn
Publikováno v:
Precision and Future Medicine, Vol 6, Iss 4, Pp 233-242 (2022)
Purpose Mesenchymal-epithelial transition tyrosine kinase receptor (MET) amplification is one of the common acquired resistance mechanisms to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). To evaluate the usefulness of scree
Externí odkaz:
https://doaj.org/article/80797f7b73f24d7e8f3b5caf7f97b856
Autor:
George Anderson
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 24 (2024)
The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on hormonal alterations driven by changes within the hypothalamus and ovarian granulosa cells, with treatment by the contraceptive pill and weight loss. However, a growin
Externí odkaz:
https://doaj.org/article/45b5bf1318d446f089f83fde2daa5682
Publikováno v:
Cells, Vol 13, Iss 1, p 28 (2023)
The involvement of the N-methyl-D-aspartate receptor (NMDAR), a glutamate-gated ion channel, in promoting the invasive growth of cancer cells is an area of ongoing investigation. Our previous findings revealed a physical interaction between NMDAR and
Externí odkaz:
https://doaj.org/article/9ac575bbdc2c43ccbd44b4316accc0fa
Autor:
Yves Combarnous, Thi Mong Diep Nguyen
Publikováno v:
Journal of Xenobiotics, Vol 12, Iss 2, Pp 64-73 (2022)
The endocrine disruptors are mostly small organic molecules developed for numerous and very diverse industrial applications. They essentially act through nuclear receptors with small and hydrophobic endogenous ligands. Nevertheless, potential adverse
Externí odkaz:
https://doaj.org/article/2fe29ac630fe460285ce34c63c3e2561