Vastatin (the NC1 domain of human type VIII collagen a1 chain) is linked to stromal reactivity and elevated in serum from patients with colorectal cancer

Autor: Lars N. Jorgensen, Morten A. Karsdal, Nicholas Willumsen

Publikováno v: Cancer Biology & Therapy. 20:692-699

Vastatin, a fragment derived from type VIII collagen, is one of the least studied collagen-derived matrikines. Vastatin can be detected in serum but little is known regarding the relevance of serum vastatin in colorectal cancer (CRC). In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb16ae712633f36f5aa08d45d2673b4
https://doi.org/10.1080/15384047.2018.1550571

Su1912 – A Serological Biomarker of Type Viii Collagen that Contains the Anti-Angiogenic Signalling Molecule, Vastatin, is Associated with the Extension of Disease in Ulcerative Colitis

Autor: Line E. Godskesen, Majken Lindholm, Morten A. Karsdal, Tina Manon-Jensen, Joachim Høg Mortensen, Lasse Langholm, Aleksander Krag, Jens Kjeldsen

Publikováno v: Gastroenterology. 156:S-657

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8905eebaf74fe3d8177240186d0e7bea
https://doi.org/10.1016/s0016-5085(19)38549-x

Fuchs Endothelial Corneal Dystrophy: A Systematic Immunofluorescence Study of Collagen Type VIII Suggests Heterogeneous Pathophysiology

Autor: Jesper Hjortdal, Nicholas S. Greenhill, Esben Nielsen, Paul F. Davis, Anders Ivarsen, Kim Nielsen

Publikováno v: Nielsen, E, Nielsen, K, Ivarsen, A, Greenhill, N S, Davis, P F & Hjortdal, J 2016, ' Fuchs Endothelial Corneal Dystrophy : A Systematic Immunofluorescence Study of Collagen Type VIII Suggests Heterogeneous Pathophysiology ', Cornea, vol. 35, no. 6, pp. 872-7 . https://doi.org/10.1097/ICO.0000000000000848

PURPOSE: The purpose of this study was to investigate the pathophysiologic heterogeneity of Fuchs endothelial corneal dystrophy (FECD).METHODS: We conducted a systematic immunofluorescence study on 39 Descemet membrane samples from FECD patients and

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https://pubmed.ncbi.nlm.nih.gov/27078008

The Role of Type VIII Collagen in Arterial Vessel Stiffening

Autor: Steffen-Sebastian Bolz, Michelle P. Bendeck, Amanda L. Mohabeer, Guangpei Hou, Hangjun Zhang, Richard K. Assoian, Scott P. Heximer, Jeffery Kroetsch

Publikováno v: Atherosclerosis Supplements. 32:98

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https://doi.org/10.1016/j.atherosclerosissup.2018.04.299

Structure and Biology of Type VIII Collagen

Autor: Lawrence E. Chun, M. Luisa Iruela-Arispe, E. Helene Sage

Publikováno v: Trends in Glycoscience and Glycotechnology, vol 4, iss 16
Iruela-Arispe, M Luisa; Chun, Lawrence E; & Sage, E Helene. (1992). Structure and Biology of Type VIII Collagen.. Trends in Glycoscience and Glycotechnology, 4(16), 188-199. doi: 10.4052/tigg.4.188. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/0z93d7tq

Type VIII collagen was initially characterized as a biosynthetic product of bovine aortic endothelial cells in vitro and thus named Endothelial Collagen(EC). The protein has now been identified in avian and mammalian species as a product secreted by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883a8f57fdb8eb6e0a8a69dacec45f70
https://doi.org/10.4052/tigg.4.188