Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Type I interferon signaling pathway"'
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Some cytokine signaling pathways can interact with interferon (IFN)-α pathway and thus regulate cell responses to IFN-α. Levels of the pro-inflammatory cytokine interleukin-17A (IL-17A) were found to be elevated in both the peri
Externí odkaz:
https://doaj.org/article/9f27070346e142f5a3f94a460b3b1c60
Akademický článek
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Autor:
Bianca Marmontel de Souza, Felipe Mateus Pellenz, Guilherme Coutinho Kullmann Duarte, Luis Henrique Santos Canani, Daisy Crispim, Cristine Dieter
Publikováno v:
Diabetes & Metabolism Journal
Background: Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6840c8ba735bf7f70524f10e97875f
https://doi.org/10.4093/dmj.2020.0194
https://doi.org/10.4093/dmj.2020.0194
Autor:
Yu-Fang Dai, An-Ping Chen, San-Shan He, Xia Huang, Qing-Chao Wu, Yun-Long Wang, Zhen-Yu Gao, Guo-Qing Yan, Lin-Chong Su, Jiao-E Sheng
Publikováno v:
Clinical Rheumatology. 41:437-452
Lupus erythematosus is an autoimmune disease that causes damage to multiple organs ranging from skin lesions to systemic manifestations. Cutaneous lupus erythematosus (CLE) is a common type of lupus erythematosus (LE), but its molecular mechanisms ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cc0611bc8f06217c548bdecdc466f7
https://doi.org/10.1007/s10067-021-05913-2
https://doi.org/10.1007/s10067-021-05913-2
Autor:
Yi Sun, Wenna Jiang, Lu Sun, Li Ren, Runfen Cheng, Zhuozhi Wang, Rui Liu, Yongzi Chen, Duo Zuo, Xinwei Zhang, Fan Tang
Publikováno v:
Cancer Biology & Medicine. 19:1029-1046
Objective: The main reasons for the poor prognoses of pancreatic adenocarcinoma (PA) patients are rapid early-stage progression, advanced stage metastasis, and chemotherapy resistance. Identification of novel diagnostic and prognostic biomarkers of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f439c1e33ab80ff954e35ad10a99718e
https://doi.org/10.20892/j.issn.2095-3941.2020.0516
https://doi.org/10.20892/j.issn.2095-3941.2020.0516
Publikováno v:
International Journal of General Medicine
Shengsheng Liu,1â 3,* Weicong Ren,1,* Jiajia Yu,1,2 Chuanyou Li,1 Shenjie Tang2 1Department of Bacteriology and Immunology, Beijing Tuberculosis and Thoracic Tumor Research Institute/Beijing Chest Hospital, Capital Medical University, Be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae90b486c4df51b8444ab4af47410bc
http://europepmc.org/articles/PMC8331204
http://europepmc.org/articles/PMC8331204
Autor:
Jing Yang, Wei Zhao, Jikai Zhang, Renfeng Fan, Peiyu Zeng, Xiaoming Yang, Kai Duan, Jinglong Deng, Xinguo Li, Tian Han, Jiayou Zhang, Huang Xiaoyuan
Publikováno v:
Aging (Albany NY)
Clinical data showed sex variability in the immune response to influenza vaccination, this study aimed to investigate differentially expressed genes (DEGs) that contribute to sex-bias immunity to quadrivalent inactivated influenza vaccines (QIVs) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8724b4b8a311f87e5f400ebb7b14177c
http://europepmc.org/articles/PMC8064175
http://europepmc.org/articles/PMC8064175
Publikováno v:
Computational and Mathematical Methods in Medicine, Vol 2020 (2020)
Computational and Mathematical Methods in Medicine
Computational and Mathematical Methods in Medicine
Pancreatic cancer (PC) is one of the most deadly cancers worldwide. To uncover the unknown novel biomarker used to indicate early diagnosis and prognosis in the molecular therapeutic field of PC is extremely of importance. Accumulative evidences indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7a17f06898b61e2dd79c4f12ca68fb
https://doi.org/10.1155/2020/6138039
https://doi.org/10.1155/2020/6138039
Autor:
Huihuang Yan, James R. Cerhan, Zhiquan Wang, Neil E. Kay, Shulan Tian, Nicholas J. Boddicker, Geffen Kleinstern, Susan L. Slager, Jeong Heon Lee, Esteban Braggio
Publikováno v:
Hum Mol Genet
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries. It has a strong genetic basis, showing a ~ 8-fold increased risk of CLL in first-degree relatives. Genome-wide association studies (GWAS) have identified 41 ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b483de8ece453796d73ff797333c69
https://doi.org/10.1093/hmg/ddaa165
https://doi.org/10.1093/hmg/ddaa165
Autor:
Min Zheng, Thirumala-Devi Kanneganti
Publikováno v:
Immunol Rev
ZBP1 has been characterized as a critical innate immune sensor of not only viral RNA products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z-RNA produced during influenza virus infection induces cell death in the form of pyroptosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644f392ae5dab2e55387bda7507b40a6
https://doi.org/10.1111/imr.12909
https://doi.org/10.1111/imr.12909