Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Type 1 Interferon"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11255-11269 (2024)
TAFRO syndrome, first reported in 2010, is a systemic inflammatory disease with a rapid onset and potentially fatal course if not treated promptly and appropriately. The name is derived from the initial letters describing the characteristic symptoms
Externí odkaz:
https://doaj.org/article/12017e9e10e546f9b9fcfc8ba857807c
Autor:
Radhika Joshi, Veronika Brezani, Gabrielle M. Mey, Sergi Guixé-Muntet, Marti Ortega-Ribera, Yuan Zhuang, Adam Zivny, Sebastian Werneburg, Jordi Gracia-Sancho, Gyongyi Szabo
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract The pathological role of interferon signaling is emerging in neuroinflammatory disorders, yet, the specific role of Interferon Regulatory Factor 3 (IRF3) in neuroinflammation remains poorly understood. Here, we show that global IRF3 deficien
Externí odkaz:
https://doaj.org/article/a6777c870b7d4b4d97a8c4e5b7383a1a
Autor:
Jakob Hjorth Von Stemann, Arnold Matovu Dungu, Maria Vispe Laguarda, Camilla Koch Ryrsø, Maria Hein Hegelund, Daniel Faurholt-Jepsen, Rikke Krogh-Madsen, Morten Bagge Hansen, Birgitte Lindegaard, Sisse Rye Ostrowski
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCytokine autoantibodies (c-aAb) have been associated with pulmonary diseases, including severe novel coronavirus disease 2019 (COVID-19) and pulmonary alveolar proteinosis. This study aimed to determine c-aAb association with community-ac
Externí odkaz:
https://doaj.org/article/569c2e37a3c4442ca51ce1c99df282c6
Autor:
Sara Bohnstedt Mørup, Preston Leung, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Maja Milojevic, Ana Milinkovic, Angelike Liappis, Line Borgwardt, Kathy Petoumenos, Roger Paredes, Shweta S. Mistry, Cameron R. MacPherson, Jens Lundgren, Marie Helleberg, Joanne Reekie, Daniel D. Murray, for the INSIGHT FIRST and START study groups
Publikováno v:
AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Human genetic contribution to HIV progression remains inadequately explained. The type 1 interferon (IFN) pathway is important for host control of HIV and variation in type 1 IFN genes may contribute to disease progression. This s
Externí odkaz:
https://doaj.org/article/8aa261a5c95940b6ad7f4516bcd362c8
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 678-699 (2024)
Abstract Cytosolic DNA sensors are a group of pattern recognition receptors (PRRs) that vary in structures, molecular mechanisms, and origins but share a common function to detect intracellular microbial DNA and trigger the innate immune response lik
Externí odkaz:
https://doaj.org/article/dc14c998a1a94601ba06e7c1c0ec4fc8
Autor:
Jin Li, Zhuxia Jia, Rongxuan Wang, Bitao Xiao, Yanan Cai, Tianshu Zhu, Weiya Wang, Xinyue Zhang, Shu Fan, Xiaolong Fan, Wenmin Han, Xuzhang Lu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMultiple myeloma (MM) is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells in bone marrow. Upfront identification of tumor subgroups with specific biological markers has the potential to improve biolo
Externí odkaz:
https://doaj.org/article/b3aa122c34cd41649136981fcedd7ee0
Autor:
Anne M. Fitzpatrick, PhD, Min Huang, BS, Ahmad F. Mohammad, BS, Susan T. Stephenson, PhD, Rishikesan Kamaleswaran, PhD, Jocelyn R. Grunwell, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100229- (2024)
Background: The innate mechanisms associated with viral exacerbations in preschool children with recurrent wheezing are not understood. Objective: We sought to assess differential gene expression in blood neutrophils from preschool children with recu
Externí odkaz:
https://doaj.org/article/229b2cfefc634b31adcfa2886058d3bb
Autor:
Daniel R. Antohi, BA, Anitha Ramu, MD, Tian Zhu, MD, Shudan Wang, MD, Michael Occidental, MD, Bijal Amin, MD, Benedict Wu, DO, PhD, Jeanie Lee, MD
Publikováno v:
JAAD Case Reports, Vol 45, Iss , Pp 50-52 (2024)
Externí odkaz:
https://doaj.org/article/851498bbf93e494091e5b1aef95a6d8e
Autor:
Alanna G. Spiteri, Tamara Suprunenko, Erin Cutts, Andrew Suen, Thomas M. Ashhurst, Barney Viengkhou, Nicholas J. C. King, Markus J. Hofer
Publikováno v:
Viruses, Vol 16, Iss 3, p 390 (2024)
CD8+ T cells are critical to the adaptive immune response against viral pathogens. However, overwhelming antigen exposure can result in their exhaustion, characterised by reduced effector function, failure to clear virus, and the upregulation of inhi
Externí odkaz:
https://doaj.org/article/26022dd0865c4e828fc5dc8f2712d9fb
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