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pro vyhledávání: '"Tynisha Thomas"'
Autor:
Cong Zhang, Jian Hua Zheng, John C. Kappes, Harris Goldstein, Tynisha Thomas, Kieran Seay, Christina Ochsenbauer
Publikováno v:
Methods in Molecular Biology ISBN: 9781493930456
Mice cannot be used as a model to evaluate HIV-1 therapeutics because they do not become infected by HIV-1 due to structural differences between several human and mouse proteins required for HIV-1 replication. This has limited their use for in vivo a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::075f36ef869d1d0aeab4f36ff81d6cb6
https://doi.org/10.1007/978-1-4939-3046-3_15
https://doi.org/10.1007/978-1-4939-3046-3_15
Autor:
Jose Silva, Heng-Keang Lim, Vedwatee Gopaul, Tynisha Thomas, Rhys Salter, Paul F. Jackson, Kevin Cook, Kenneth J. Rhodes, Carlo Sensenhauser, Stefanie Rassnick, David C. Evans, Chen Jie, Robert Preston, Brian C. Shook
Publikováno v:
Chemical Research in Toxicology. 24:1012-1030
2-Amino-4-phenyl-8-pyrrolidin-1-ylmethyl-indeno[1,2-d]pyrimidin-5-one (1) is a novel and potent selective dual A(2A)/A(1) adenosine receptor antagonist from the arylindenopyrimidine series that was determined to be genotoxic in both the Ames and Mous