Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Tyms AS"'
Publikováno v:
Epidemiology and Infection, 1988 Dec 01. 101(3), 483-494.
Externí odkaz:
https://www.jstor.org/stable/3863284
Autor:
Stanier, Philip, Taylor, Debra L., Kitchen, Alan D., Wales, Nicholas, Tryhorn, Yvonne, Tyms, A. Stanley
Publikováno v:
BMJ: British Medical Journal, 1989 Oct 01. 299(6704), 897-898.
Externí odkaz:
https://www.jstor.org/stable/29705584
Autor:
Tyms, James D.
Publikováno v:
Journal of Religious Thought. Spring/Summer75, Vol. 32 Issue 1, p22. 14p.
Autor:
Tyms, James D.
Publikováno v:
Journal of Religious Thought. Fall86/Winter87, Vol. 43 Issue 2, p73. 9p.
Autor:
Daniel Schirlin, Debra L. Taylor, C. G. Bridges, P. S. Ahmed, J.-M. Hornsperger, Celine Tarnus, A. S. Tyms, V. Van Dorsselaer, T M Brennan
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:205-214
MDL 74,695, a novel dipeptide-like compound containing the ‘difluorostatone type’ transition state mimic and a potent inhibitor of the human immunodeficiency virus (HIV) proteinase, was investigated for anti-HIV activity in vitro. The compound sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f943e976d09e28100cd46fd398973d7
https://doi.org/10.1177/095632029700800304
https://doi.org/10.1177/095632029700800304
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:253-260
MDL 74968 (9-[2-methylidene-3-(phosphonomethoxy)-propyl]guanine), a novel acyclonucleotide derivative of guanine, inhibited human immunodeficiency virus type 1 (HIV-1) replication in vitro with activity comparable to that of adefovir (PMEA; 9-(2-phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451ceceee9bb58c59713999e498fb867
https://doi.org/10.1177/095632029600700505
https://doi.org/10.1177/095632029600700505
Autor:
J M Hornsperger, A. S. Tyms, J F Navé, C G Bridges, Debra Taylor, P Casara, P S Ahmed, T. M. Brennan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1072-1077
The novel acyclonucleotide derivative of guanine, 9-[2-methylidene-3-(phosphonomethoxy)propyl] guanine (MDL 74,968), had antiviral activity comparable to those of 9-(2-phosphonomethoxyethyl) adenine (PMEA) and 2',3'-dideoxyinosine against laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db8c5344accd5aff341bdbd7bf1eacc
https://doi.org/10.1128/aac.40.5.1072
https://doi.org/10.1128/aac.40.5.1072
Autor:
Michael T. Kenny, Patrick Casara, A. Stanley Tyms, Jean-François Nave, Serge HalazyS, Debra L. Taylor
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:179-184
The synthesis, phosphorylation by guanylate kinase, anti HIV-1 and anti-herpesvirus activity of two acyclic dienyl phosphonate derivatives of guanine are described. (E)-9-(5-phosphono-3-methylene-4-pentenyl)guanine (4) was identified as an excellent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efdd37e7f534046862bdd264d556eb2
https://doi.org/10.1016/0960-894x(95)00585-h
https://doi.org/10.1016/0960-894x(95)00585-h
Publikováno v:
Antiviral Chemistry and Chemotherapy. 6:307-311
The basis of azidothymidine (AZT) insensitivity in the human JM T-cell line has been investigated. It was shown that uptake of radiolabelled thymidine or AZT into cellular acid-soluble pools of JM cells was about 10-fold lower than that seen in AZT-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc9483d912d147262110978d1bca3557
https://doi.org/10.1177/095632029500600504
https://doi.org/10.1177/095632029500600504
Publikováno v:
Antiviral Chemistry and Chemotherapy. 6:143-152
The anti-human immunodeficiency virus type 1 (HIV-1) activity of the α-glucosidase 1 inhibitor 6-0-butanoylcastanospermine (MDL 28574) was assessed in combination with the 2′,3′-dideoxynucleoside analogues zidovudine (AZT), didanosine (ddl) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593b8e597490bef7e981e60f2e2727b0
https://doi.org/10.1177/095632029500600303
https://doi.org/10.1177/095632029500600303