Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tyler W.E. Steele"'
Autor:
Tyler W.E. Steele, Zachary Spires, Charles B. Jones, Jose M. Eltit, Richard A. Glennon, Malgorzata Dukat
Publikováno v:
Neuropharmacology
Clandestine chemists are currently exploiting the pyrrolidinophenone scaffold to develop new designer drugs that carry the risk of abuse and overdose. These drugs promote addiction through the rewarding effects of increased dopaminergic neurotransmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c03ca5a997a0609249cdcbad8598d0
https://pubmed.ncbi.nlm.nih.gov/34619165
https://pubmed.ncbi.nlm.nih.gov/34619165
Autor:
Jose M. Eltit, Tyler W.E. Steele
Publikováno v:
Psychopharmacology. 236:973-988
The appearance of stimulant-class new psychoactive substances (NPS) is a frequent and significant problem in our society. Cathinone variants are often sold illegally as 3,4-methylenedioxy methamphetamine (“ecstasy”) or disguised for legal sale us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1c5b8294bb8cc0985bd24f0e5ffef6
https://doi.org/10.1007/s00213-018-5103-5
https://doi.org/10.1007/s00213-018-5103-5
Autor:
Montserrat Samsó, Tyler W.E. Steele
Ryanodine receptors (RyRs) are large conductance intracellular channels controlling intracellular calcium homeostasis in myocytes, neurons, and other cell types. Loss of RyR’s constitutive cytoplasmic partner FKBP results in channel sensitization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b680502bb970ceff737cac58b72e02
https://europepmc.org/articles/PMC6494473/
https://europepmc.org/articles/PMC6494473/
Autor:
Jose M. Eltit, Subramaniam Ananthan, S. Stevens Negus, Megan J. Moerke, Matthew L. Banks, Amy R. Johnson, Tyler W.E. Steele, Surendra K. Saini, Kelen Freitas
Drugs that inhibit the dopamine (DA) transporter (DAT) include both therapeutic agents and abused drugs. Recent studies identified a novel series of putative allosteric DAT inhibitors, but the in vivo effects of these compounds are unknown. This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ba6a0c02d3b5f3344c43c6fe3f478f
https://europepmc.org/articles/PMC6170971/
https://europepmc.org/articles/PMC6170971/
Publikováno v:
Biophysical Journal. 116:557a-558a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76123d86061706218e883c176eafb567
https://doi.org/10.1016/j.bpj.2018.11.2998
https://doi.org/10.1016/j.bpj.2018.11.2998
Publikováno v:
ResearcherID
The ryanodine receptor (RyR) is an intracellular ion channel with an important role in depolarization-induced Ca2+ release in excitable cells. For the skeletal muscle isoform RyR1, the open and closed conformations were determined at 10 A resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a58feb521165ddd00f3ab02f7823ec
https://doi.org/10.1016/j.bpj.2012.11.2457
https://doi.org/10.1016/j.bpj.2012.11.2457
Autor:
Tyler W.E. Steele, Louis J. De Felice
Publikováno v:
Biophysical Journal. (2):462a
The existence of a solved structure for a dopamine transporter drastically changes the landscape for investigation of the mechanism of monoamine transporter function. While previous structures for LeuT have shed light on transport mechanisms, and tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd62b64132b320465bf4323decf723de