Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tyler W Doughty"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006216 (2016)
During mitosis chromosomes are condensed to facilitate their segregation, through a process mediated by the condensin complex. Although several factors that promote maximal condensin activity during mitosis have been identified, the mechanisms that d
Externí odkaz:
https://doaj.org/article/813734c1c2d5457984168f21b19d1826
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Eukaryotic organisms, like the model yeast S. cerevisiae, have linear chromosomes that facilitate organization and protection of nuclear DNA. A recent work described a stepwise break/repair method that enabled fusion of the 16 chr
Externí odkaz:
https://doaj.org/article/c0491e43106544c1bf86fdcb0a7ff653
Autor:
Tyler W. Doughty, Iván Domenzain, Aaron Millan-Oropeza, Noemi Montini, Philip A. de Groot, Rui Pereira, Jens Nielsen, Céline Henry, Jean-Marc G. Daran, Verena Siewers, John P. Morrissey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Fermentation parameters of industrial processes are often not the ideal growth conditions for industrial microbes. Here, the authors reveal that young genes are more responsive to environmental stress than ancient genes using a new gene age assignmen
Externí odkaz:
https://doaj.org/article/453efe3e004741ae8e4b9a901b4ed692
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Doughty, T W, Yu, R, Chao, L F I, Qin, Z, Siewers, V & Nielsen, J 2021, ' A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance ', BMC Genomics, vol. 22, no. 1, 688 . https://doi.org/10.1186/s12864-021-07947-x
BMC Genomics
Doughty, T W, Yu, R, Chao, L F I, Qin, Z, Siewers, V & Nielsen, J 2021, ' A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance ', BMC Genomics, vol. 22, no. 1, 688 . https://doi.org/10.1186/s12864-021-07947-x
BMC Genomics
Background Eukaryotic organisms, like the model yeast S. cerevisiae, have linear chromosomes that facilitate organization and protection of nuclear DNA. A recent work described a stepwise break/repair method that enabled fusion of the 16 chromosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba594ac0aac1310496ea8cd4ab0cb54d
https://doaj.org/article/c0491e43106544c1bf86fdcb0a7ff653
https://doaj.org/article/c0491e43106544c1bf86fdcb0a7ff653
Autor:
Noemi, Montini, Tyler W, Doughty, Iván, Domenzain, Darren A, Fenton, Pavel V, Baranov, Ronan, Harrington, Jens, Nielsen, Verena, Siewers, John P, Morrissey
Publikováno v:
Microbiology (Reading, England). 168(3)
It is important to understand the basis of thermotolerance in yeasts to broaden their application in industrial biotechnology. The capacity to run bioprocesses at temperatures above 40 °C is of great interest but this is beyond the growth range of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93b1df21415313b49c1953ba8962a763
https://pubmed.ncbi.nlm.nih.gov/35333706
https://pubmed.ncbi.nlm.nih.gov/35333706
Background:Eukaryotic organisms, like the model yeast S. cerevisiae, have linear chromosomes that facilitate organization and protection of nuclear DNA. A recent work described a stepwise break/repair method that enabled fusion of the sixteen chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7b5bbf3713ecee48249ba637655cd8
https://doi.org/10.21203/rs.3.rs-458332/v1
https://doi.org/10.21203/rs.3.rs-458332/v1
Autor:
Jens Nielsen, Jean-Marc Daran, Tyler W. Doughty, Noemi Montini, Aaron Millan-Oropeza, Philip A. de Groot, John P. Morrissey, Iván Domenzain, Verena Siewers, Céline Henry, Rui Pedro Gomes Pereira
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, 11(1)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, 11(1)
The Saccharomycotina subphylum (budding yeasts) spans 400 million years of evolution and includes species that thrive in diverse environments. To study niche-adaptation, we identify changes in gene expression in three divergent yeasts grown in the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3d29e853f7a1d2b6b89810b34f188e
https://doi.org/10.1101/660274
https://doi.org/10.1101/660274
Autor:
John P. Morrissey, Jens Nielsen, Ivan Dmenzain Del Castillo Cerecer, Pavel Baranov, Javier A. Varela, Noemi Montini, Darren Anthony Fenton, Verena Siewers, Tyler W. Doughty
Publikováno v:
Access Microbiology. 1
Microbial production strains need to operate under sub- optimal growth conditions such as low pH, high osmolarity and thermal stress. The capacity to carry out industrial fermentations at higher temperatures reduces the risk of bacterial contaminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf4b6102c64f718c2497c5fb76eddc3
https://doi.org/10.1099/acmi.ac2019.po0317
https://doi.org/10.1099/acmi.ac2019.po0317
Autor:
Brendan J. Hilbert, Robert A. Coover, William E. Royer, Tyler W. Doughty, Glen E. Kellogg, Sudha Korwar, Keith C. Ellis, Ian M. Love, Benjamin L. Morris, Steven R. Grossman, Hardik I. Parikh
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:2707-2715
C-terminal Binding Protein (CtBP) is a transcriptional co-regulator that downregulates the expression of many tumor-suppressor genes. Utilizing a crystal structure of CtBP with its substrate 4-methylthio-2-oxobutyric acid (MTOB) and NAD+ as a guide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c03beda637ff225d770b79b990edbc9
https://doi.org/10.1016/j.bmc.2016.04.037
https://doi.org/10.1016/j.bmc.2016.04.037
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 7, p e1006216 (2016)
PLoS Genetics, Vol 12, Iss 7, p e1006216 (2016)
During mitosis chromosomes are condensed to facilitate their segregation, through a process mediated by the condensin complex. Although several factors that promote maximal condensin activity during mitosis have been identified, the mechanisms that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7db799af4d10717fecab622b9dca69e
http://europepmc.org/articles/PMC4963108
http://europepmc.org/articles/PMC4963108