Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Tyler T Cooper"'
Autor:
Tyler T Cooper, Lynne-Marie Postovit
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002297 (2023)
The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that suppo
Externí odkaz:
https://doaj.org/article/4da6dfdabce547c7a6c8c4dec6477107
Publikováno v:
Stem Cells. 40:239-259
Metabolism plays a crucial role for cell survival and function; however, recent evidence has implicated it in regulating embryonic development. In the embryo, the inner cell mass undergoes orchestrated cellular divisions resulting in the formation of
Autor:
Sohrab N. Ali, Thamara K. Dayarathna, Aymon N. Ali, Tijani Osumah, Mohamed Ahmed, Tyler T. Cooper, Nicholas E. Power, Dongxing Zhang, Dajung Kim, Rachel Kim, Andre St. Amant, Jinqiang Hou, Thomas Tailly, Jun Yang, Len Luyt, Paul A. Spagnuolo, Jeremy P. Burton, Hassan Razvi, Hon S. Leong
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 11 (2018)
Kidney stone disease involves the aggregation of stone-forming salts consequent to solute supersaturation in urine. The development of novel therapeutic agents for this predominantly metabolic and biochemical disorder have been hampered by the lack o
Externí odkaz:
https://doaj.org/article/6f87902d61b54feb83e0b152c99374ab
Publikováno v:
Journal of biomedical materials research. Part AREFERENCES.
Recognizing the cell-instructive capacity of the extracellular matrix (ECM), this study investigated the effects of expanding human adipose-derived stromal cells (hASCs) on ECM-derived microcarriers fabricated from decellularized adipose tissue (DAT)
1.AbstractWnt and Hh are known signalling pathways involved in neural differentiation and recent work has shown the cell cycle regulator, Never in Mitosis Kinase 2 (Nek2) is able to regulate both pathways. Despite its known function in pathway regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1903984b56b42a1abc9c6b63319085bd
https://doi.org/10.1101/2022.08.23.504995
https://doi.org/10.1101/2022.08.23.504995
Autor:
Danielle M. McRae, Gillian I. Bell, Tyler T. Cooper, Stephen E. Sherman, Jun Ma, Stephen H. Pasternak, François Lagugné-Labarthet, David A. Hess, Gilles A. Lajoie, Thamara Dayarathna
Publikováno v:
Stem Cells and Development. 30:247-264
The secretome of mesenchymal stromal cells (MSCs) is enriched for biotherapeutic effectors contained within and independent of extracellular vesicles (EVs) that may support tissue regeneration as an injectable agent. We have demonstrated that the int
Autor:
Nina M Ćulum, Jiahui Liu, Gilles A. Lajoie, Tyler T. Cooper, François Lagugné-Labarthet, Lynne-Marie Postovit, Yang Xin Fu, Thamara Dayarathna, Stephen H. Pasternak
Publikováno v:
Chemistry Publications
Ovarian cancer is the most lethal gynecological malignancy, owing to the fact that most cases are diagnosed at a late stage. To improve prognosis and reduce mortality, we must develop methods for the early diagnosis of ovarian cancer. A step towards
Autor:
Ramy Ibrahim, Jaffar Ahmad Alhilli, Tyler T. Cooper, Irina Dashkova, Judah Guy, Anjula Gandhi, Mohammad Zaman
Publikováno v:
Clinical Medicine Insights: Blood Disorders, Vol 2013, Iss 6, Pp 1-5 (2013)
Externí odkaz:
https://doaj.org/article/952817f3df2a463a9344a277e98fc3f4
Publikováno v:
Stem Cells and Development. 29:895-910
Fluorescent-activated cell sorting (FACS) remains a powerful tool to enrich blood-derived progenitor cells for the establishment of highly proliferative endothelial colony-forming cells (ECFC). Further investigation remains necessary to determine whe
Autor:
Miljan Kuljanin, David A. Hess, Tyler T. Cooper, Gillian I. Bell, Stephen E. Sherman, Jun Ma, Gilles A. Lajoie, Shauna E. Jose
Publikováno v:
Stem Cells. 38:666-682
Multipotent/mesenchymal stromal cells (MSCs) exist within a variety of postnatal tissues; however, global proteomic analyses comparing tissue-specific MSC are limited. Using human bone marrow (BM)-derived MSCs as a gold standard, we used label-free m