Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tyler Scherzi"'
Autor:
Catherine L. Grimes, Paul M. Dunman, Elizabeth A. D'Ambrosio, Samer S. Daher, Rodrigo B. Andrade, Tyler Scherzi
Publikováno v:
Bioorg Med Chem
Small molecule target identification is a critical step in modern antibacterial drug discovery, particularly against multi-drug resistant pathogens. Albocycline (ALB) is a macrolactone natural product with potent activity against methicillin-resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d27e28fa07e4f3416d3a834735292d5
https://europepmc.org/articles/PMC7891091/
https://europepmc.org/articles/PMC7891091/
Autor:
Rachel A. F. Wozniak, Michaelle Chojnacki, Nicole D. Pecora, Alesa Philbrick, Paul M. Dunman, Tyler Scherzi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Bacterial keratitis causes significant blindness, yet antimicrobial resistance has rendered current treatments ineffective. Polymyxin B-trimethoprim (PT) plus rifampin has potent in vitro activity against Staphylococcus aureus and Pseudomonas aerugin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3afeb5d81641bdaa08e1f598482dd2
https://doi.org/10.1128/aac.00777-19
https://doi.org/10.1128/aac.00777-19
Publikováno v:
Bioorg Med Chem Lett
Albocycline (ALB) is a unique macrolactone natural product with potent, narrow-spectrum activity against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate (VISA), and vancomycin-resistant S. aureus (VRSA) strains (MIC = 0.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1664f0afbbc29f402981789f33acdec8
https://doi.org/10.1016/j.bmcl.2020.127509
https://doi.org/10.1016/j.bmcl.2020.127509