Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tyler Rhinesmith"'
Autor:
Leo Kiss, Tyler Rhinesmith, Jakub Luptak, Claire F. Dickson, Jonas Weidenhausen, Shannon Smyly, Ji-Chun Yang, Sarah L. Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C. James
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitin
Externí odkaz:
https://doaj.org/article/9847497c03534f53b81f80ff92484d91
Autor:
Alberto Diaz-Ruiz, Tyler Rhinesmith, Laura C. D. Pomatto-Watson, Nathan L. Price, Farzin Eshaghi, Margaux R. Ehrlich, Jacqueline M. Moats, Melissa Carpenter, Annamaria Rudderow, Sebastian Brandhorst, Julie A. Mattison, Miguel A. Aon, Michel Bernier, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the contribution of diet composition, calories and length of fasting in health maintenance is still challenging. Here the authors compare the effects of cycles of intermittent very low calorie intake achieved with a plant-based fasting
Externí odkaz:
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Robert Root-Bernstein, Andrew G. Baker, Tyler Rhinesmith, Miah Turke, Jack Huber, Adam W. Brown
Publikováno v:
Life, Vol 13, Iss 2, p 265 (2023)
The standard approach to exploring prebiotic chemistry is to use a small number of highly purified reactants and to attempt to optimize the conditions required to produce a particular end product. However, purified reactants do not exist in nature. W
Externí odkaz:
https://doaj.org/article/ea591062deae4d439096dd76370d6b08
Autor:
Farzin Eshaghi, Sebastian Brandhorst, Tyler Rhinesmith, Jacqueline M. Moats, Laura C. D. Pomatto-Watson, Alberto Diaz-Ruiz, Julie A. Mattison, Miguel A. Aon, Nathan L. Price, Annamaria L Rudderow, Melissa Carpenter, Valter D. Longo, Margaux R. Ehrlich, Rafael de Cabo, Michel Bernier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Diet composition, calories, and fasting times contribute to the maintenance of health. However, the impact of very low-calorie intake (VLCI) achieved with either standard laboratory chow (SD) or a plant-based fasting mimicking diet (FMD) is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb9b9f429efca44c8c5b24289160c0e
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Leo Kiss, Tyler Rhinesmith, Claire F Dickson, Jonas Weidenhausen, Shannon Smyly, Jakub Luptak, Ji-Chun Yang, Sarah L Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C James
TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitination mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff087e88dc61ef593889cbe848b8038
https://doi.org/10.1101/2022.06.29.498105
https://doi.org/10.1101/2022.06.29.498105
Autor:
Tyler Rhinesmith, Anna Albecka, Leo C. James, Marina Vaysburd, Dean Clift, David M Favara, Sarah L Caddy, Helen Baxendale
Publikováno v:
The EMBO Journal
The humoral immune response to SARS‐CoV‐2 results in antibodies against spike (S) and nucleoprotein (N). However, whilst there are widely available neutralization assays for S antibodies, there is no assay for N‐antibody activity. Here, we pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40171580d398a5595c020e71fc8c5d8
http://europepmc.org/articles/PMC8408615
http://europepmc.org/articles/PMC8408615
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d517631faadb2c3b927ce86c3784b28
https://doi.org/10.1096/fasebj.2019.33.1_supplement.755.6
https://doi.org/10.1096/fasebj.2019.33.1_supplement.755.6
Publikováno v:
Journal of Molecular Recognition. 29:296-302
The intracellular recycling of ascorbic acid from dehydroascorbic acid by the glutathione-glutathione reductase system has been well-characterized. We propose that extracellular recycling of ascorbic acid is performed in a similar manner by cysteine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0098b53d7757a5ff7ef441102455ecd
https://doi.org/10.1002/jmr.2530
https://doi.org/10.1002/jmr.2530
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2602
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2602 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2602 (2017)
The causes of insulin resistance are not well-understood in either type 1 or type 2 diabetes. Insulin (INS) is known to undergo rapid non-enzymatic covalent conjugation to glucose or other sugars (glycation). Because the insulin receptor (IR) has INS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581dc571a1004da560253ea3a5fcd941
Publikováno v:
Journal of Visualized Experiments.
There are many well-developed methods for purifying and studying single proteins and peptides. However, most cellular functions are carried out by networks of interacting protein complexes, which are often difficult to investigate because their bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa32ba2c3fa961bea1e0be2efefdfad
https://doi.org/10.3791/55341-v
https://doi.org/10.3791/55341-v