Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tyler M. Hudish"'
Autor:
Lori D. Dwyer‐Nield, Debbie G. McArthur, Tyler M. Hudish, Laura I. Hudish, Carol Mirita, Kayla Sompel, Alex J. Smith, Kiana Alavi, Moumita Ghosh, Daniel T. Merrick, Meredith A. Tennis, Robert L. Keith
Publikováno v:
International Journal of Cancer. 151:2195-2205
The N-nitroso-trischloroethylurea (NTCU)-induced mouse model of squamous lung carcinoma recapitulates human disease from premalignant dysplasia through invasive tumors, making it suitable for preclinical chemoprevention drug testing. Pioglitazone is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8cce7f7c1e830b58a049e7bf087ed6
https://doi.org/10.1002/ijc.34210
https://doi.org/10.1002/ijc.34210
Autor:
Robert L. Keith, Daniel T. Merrick, Stephen P. Malkoski, Timothy G. Cleaver, Micah S. Johnson, Anthony B. Mozer, Laura I. Opincariu, Tyler M. Hudish
PDF file - 1.3MB, H/E (A) and IHC staining of adenocarcinoma with CK5/6 (B), p63 (C), TTF-1 (D), and NAPSIN-A (E). magnification: 400X.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e012268fcd60c8c8eb6d1348d32f69
https://doi.org/10.1158/1940-6207.22524086
https://doi.org/10.1158/1940-6207.22524086
Autor:
Robert L. Keith, Daniel T. Merrick, Stephen P. Malkoski, Timothy G. Cleaver, Micah S. Johnson, Anthony B. Mozer, Laura I. Opincariu, Tyler M. Hudish
PDF file - 69K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d911ca45d76b86aa228098eae124113
https://doi.org/10.1158/1940-6207.22524083
https://doi.org/10.1158/1940-6207.22524083
Autor:
Robert L. Keith, Daniel T. Merrick, Stephen P. Malkoski, Timothy G. Cleaver, Micah S. Johnson, Anthony B. Mozer, Laura I. Opincariu, Tyler M. Hudish
PDF file - 99K, The number of animals in each score category from the behavioral index scoring system in the 4mM and 8mM treatment groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7524873a0fe84d6708c63a91f9e28da2
https://doi.org/10.1158/1940-6207.22524080.v1
https://doi.org/10.1158/1940-6207.22524080.v1
Autor:
Robert L. Keith, Daniel T. Merrick, Stephen P. Malkoski, Timothy G. Cleaver, Micah S. Johnson, Anthony B. Mozer, Laura I. Opincariu, Tyler M. Hudish
PDF file - 152K, weight fluctuation in animals receiving 40mM NTCU. This group was divided into two waves (panels A and B), with differing periods of suspensions (arrows) throughout the study. Weight recovery is observable following treatment suspens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d40be1644c2d80a82488004d275cd04
https://doi.org/10.1158/1940-6207.22524092.v1
https://doi.org/10.1158/1940-6207.22524092.v1
Autor:
Stephen P. Malkoski, Robert L. Keith, Anthony B. Mozer, Timothy G. Cleaver, Tyler M. Hudish, Daniel T. Merrick, Micah S. Johnson, Laura I. Opincariu
Publikováno v:
Cancer Prevention Research. 5:283-289
Squamous cell carcinoma (SCC) and premalignant endobronchial lesions have been difficult to study in murine models. In this study, we evaluate the topical N-nitroso-tris-chloroethylurea (NTCU) murine SCC model, determine the extent to which resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852211970b0f160e0b0c71257057ebae
https://doi.org/10.1158/1940-6207.capr-11-0257
https://doi.org/10.1158/1940-6207.capr-11-0257
Autor:
Amy M. Meyer, Tyler M. Hudish, Robert Stearman, Shuh Narumiya, Robert L. Keith, Mary C.M. Weiser-Evans, Robert A. Winn, Raphael A. Nemenoff, Anthony B. Mozer, Amy Snee, Mark W. Geraci
Publikováno v:
Cancer Prevention Research. 1:349-356
Overexpression of prostacyclin synthase (PGIS) decreases lung tumor multiplicity in chemical- and cigarette-smoke–induced murine lung cancer models. Prostacyclin signals through a single G-protein–coupled receptor (IP), which signals through cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089d2da20c213c8940a68970819e878e
https://doi.org/10.1158/1940-6207.capr-08-0145
https://doi.org/10.1158/1940-6207.capr-08-0145
Autor:
Micah Johnson, Ajay A. Wagh, Elizabeth F. Redente, Lori D. Dwyer-Nield, Robert L. Keith, Tyler M. Hudish
Publikováno v:
A64. LOCAL AND SYSTEMIC EFFECTS OF SMOKE EXPOSURE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::903cadc102a128e47413ecf51400c411
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2011
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2011
Introduction We hypothesized that the combination of the EGFR tyrosine kinase inhibitor (TKI) gefitinib with the powerful chemopreventive manipulation of lung-specific transgenic prostacyclin synthase (PGIS) overexpression on tumorigenesis in FVB/N m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cf8c8f3917f5632061ad55c7fe0cc1
https://europepmc.org/articles/PMC3098617/
https://europepmc.org/articles/PMC3098617/
Autor:
Robert L, Keith, Mark W, Geraci, S Patrick, Nana-Sinkam, Richard M, Breyer, Tyler M, Hudish, Amy M, Meyer, Alvin M, Malkinson, Lori D, Dwyer-Nield
Publikováno v:
Anticancer research. 26(4B)
Manipulating prostaglandin (PG) production modulates tumor development. Elevated PGI2 production prevents murine lung cancer, while decreasing PGE2 content protects against colon cancer. PGE2 receptor subtype 2 (EP2) -deficient mice were hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08d931a1f14a665f713617beb6c3356e
https://pubmed.ncbi.nlm.nih.gov/16886605
https://pubmed.ncbi.nlm.nih.gov/16886605