Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tyler Lalonde"'
Autor:
Rebecca Sullivan, BSc, Varinder K. Randhawa, PhD, MD, Tyler Lalonde, PhD, Tina Yu, BSc, Bob Kiaii, MD, Leonard Luyt, PhD, Gerald Wisenberg, MD, Savita Dhanvantari, PhD
Publikováno v:
CJC Open, Vol 3, Iss 2, Pp 182-194 (2021)
Background: The hormone ghrelin and its receptor, the growth hormone secretagogue receptor (GHSR) are expressed in myocardium. GHSR binding activates signalling pathways coupled to cardiomyocyte survival and contractility. These properties have made
Externí odkaz:
https://doaj.org/article/493757db3f244b5bac5b6e5f40162534
Autor:
Ahmed Abbas MSc, Lihai Yu PhD, Tyler Lalonde BSc, Derek Wu BSc, Jonathan D. Thiessen PhD, Leonard G. Luyt PhD, Savita Dhanvantari PhD
Publikováno v:
Molecular Imaging, Vol 17 (2018)
One-third of patients with heart disease develop heart failure, which is diagnosed through imaging and detection of circulating biomarkers. Imaging strategies reveal morphologic and functional changes but fall short of detecting molecular abnormaliti
Externí odkaz:
https://doaj.org/article/347f82c48655400bafc3a69fbf90d32e
Autor:
Tina Yu, Tyler Lalonde, Rebecca Sullivan, Leonard G. Luyt, Varinder K. Randhawa, Gerald Wisenberg, Savita Dhanvantari, Bob Kiaii
Publikováno v:
CJC Open, Vol 3, Iss 2, Pp 182-194 (2021)
CJC Open
CJC Open
Background: The hormone ghrelin and its receptor, the growth hormone secretagogue receptor (GHSR) are expressed in myocardium. GHSR binding activates signalling pathways coupled to cardiomyocyte survival and contractility. These properties have made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fba759694c7aa60ea92ce902a415a56
https://doi.org/10.1016/j.cjco.2020.10.015
https://doi.org/10.1016/j.cjco.2020.10.015
Publikováno v:
ChemBioChem
ChemRxiv
Chembiochem
ChemRxiv
Chembiochem
With the current trajectory of the 2019‐nCoV outbreak unknown, public health and medicinal measures will both be needed to contain spreading of the virus and to optimize patient outcomes. Although little is known about the virus, an examination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a7bd906393874b6d1cf204723a8430
https://doi.org/10.1002/cbic.202000047
https://doi.org/10.1002/cbic.202000047
Autor:
Antonela S. Fittipaldi, Daniel Castrogiovanni, Daniela Lufrano, Camila Saenz, Pablo N. De Francesco, Tyler Lalonde, Leonard G. Luyt, Sonia Cantel, Jean-Alain Fehrentz, María F. Andreoli, Mario Perello
Publikováno v:
Life Sciences. 313:121305
Since plasma ghrelin can undergo des-acylation and proteolysis, the aim of this study was to investigate the extent to which an enhancement of these reactions is associated to the decrease of ghrelin in plasma after food intake or in individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebcdec6a29e7336f7c73dcc4a4e7534
https://doi.org/10.1016/j.lfs.2022.121305
https://doi.org/10.1016/j.lfs.2022.121305
Autor:
Tyler Lalonde, Ge Yu, Shuhua G Li, Wenshe R. Liu, Kai S Yang, Chia-Chuan Cho, Yuchen Qiao, Shiqing Xu
Publikováno v:
Chemmedchem
As the pathogen of COVID‐19, SARS‐CoV‐2 encodes two essential cysteine proteases that process the pathogen's two large polypeptide products pp1a and pp1ab in the human cell host to form 15 functionally important, mature nonstructural proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3593d50b770e38f53ed6fb27820e5761
https://pubmed.ncbi.nlm.nih.gov/35132799
https://pubmed.ncbi.nlm.nih.gov/35132799
Autor:
Mark Milne, Ryan R. Maar, Tyler Lalonde, Neha Sharma, Stephanie M. Barbon, Leonard G. Luyt, Joe B. Gilroy
Publikováno v:
RSC advances. 10(32)
Two new fluorescence imaging probes have been synthesized by incorporating a versatile alkyne-substituted boron difluoride formazanate precursor with peptides through copper-catalyzed alkyne–azide cycloaddition. The formazanate dye was appended to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eed818ac19a90e7d07a739a563903e6
https://pubmed.ncbi.nlm.nih.gov/35518290
https://pubmed.ncbi.nlm.nih.gov/35518290
Autor:
Milan M. Fowkes, Tyler Lalonde, Leonard G. Luyt, Jinqiang Hou, Savita Dhanvantari, Pierre E. Thibeault, Mark Milne, Rithwik Ramachandran
Publikováno v:
Physiology and Pharmacology Publications
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The growth hormone secretagogue receptor type 1a (GHS-R1a) is a class A rhodopsin-like G protein coupled receptor (GPCR) that is expressed in a variety of human tissues and is differentially expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe3cf7f3182c1f648ca37450afdb700
https://pubmed.ncbi.nlm.nih.gov/31469937
https://pubmed.ncbi.nlm.nih.gov/31469937
Autor:
Pablo Nicolás de Francesco, Leonard G. Luyt, Tyler Lalonde, Agustina Cabral, Mario Perello, Maia Uriarte, Gimena Fernandez, Sebastián A. Trejo, Daniel Castrogiovanni
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
The stomach-derived hormone ghrelin mainly acts in the brain. Studies in mice have shown that the accessibility of ghrelin into the brain is limited and that it mainly takes place in some circumventricular organs, such as the median eminence. Notably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ba312af60a80fb7a39b51e4daae1c9
http://sedici.unlp.edu.ar/handle/10915/145491
http://sedici.unlp.edu.ar/handle/10915/145491
Autor:
Savita Dhanvantari, Leonard G. Luyt, Michael S. Kovacs, Milan M. Fowkes, Lihai Yu, Tyler Lalonde
Publikováno v:
European journal of medicinal chemistry. 157
The ghrelin receptor is a seven-transmembrane (7-TM) receptor known to have an increased level of expression in human carcinoma and heart failure. Recent work has focused on the synthesis of positron emission tomography (PET) probes designed to targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472e505f2014888137b7dd8387a84f15
https://pubmed.ncbi.nlm.nih.gov/30282322
https://pubmed.ncbi.nlm.nih.gov/30282322