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Autor:
Tyler Keate, Reshma Shetty, Craig S. Walker, James E. Garrett, Pradip K. Bandyopadhyay, Baldomero M. Olivera
Publikováno v:
Proceedings of the National Academy of Sciences. 99:1264-1269
The posttranslational γ-carboxylation of glutamate residues in secreted proteins to γ-carboxyglutamate is carried out by the vitamin K-dependent enzyme γ-glutamyl carboxylase. γ-Carboxylation has long been thought to be a biochemical specializati