Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Tyler J. Loftus"'
Autor:
Jeremy A. Balch, A. Hayes Chatham, Philip K. W. Hong, Lauren Manganiello, Naveen Baskaran, Azra Bihorac, Benjamin Shickel, Ray E. Moseley, Tyler J. Loftus
Publikováno v:
Frontiers in Artificial Intelligence, Vol 7 (2024)
BackgroundThe algorithmic patient preference predictor (PPP) has been proposed to aid in decision making for incapacitated patients in the absence of advanced directives. Ethical and legal challenges aside, multiple practical barriers exist for build
Externí odkaz:
https://doaj.org/article/8898f2519add42ec8721393d20df11a0
Autor:
Adam D. Price, Ellen R. Becker, Evan L. Barrios, Monty B. Mazer, Patrick W. McGonagill, Christian B. Bergmann, Michael D. Goodman, Robert W. Gould, Mahil Rao, Valerie E. Polcz, Tamara A. Kucaba, Andrew H. Walton, Sydney Miles, Julie Xu, Muxuan Liang, Tyler J. Loftus, Philip A. Efron, Kenneth E. Remy, Scott C. Brakenridge, Vladimir P. Badovinac, Thomas S. Griffith, Lyle L. Moldawer, Richard S. Hotchkiss, Charles C. Caldwell
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis is a complex clinical syndrome characterized by a heterogenous host immune response. Historically, static protein and transcriptomic metrics have been employed to describe the underlying biology. Here, we tested the hypothesis that
Externí odkaz:
https://doaj.org/article/0d40c4cf70d04695a92503d2f0ae310b
Autor:
Yuanfang Ren, Yanjun Li, Tyler J. Loftus, Jeremy Balch, Kenneth L. Abbott, Matthew M. Ruppert, Ziyuan Guan, Benjamin Shickel, Parisa Rashidi, Tezcan Ozrazgat-Baslanti, Azra Bihorac
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Using clustering analysis for early vital signs, unique patient phenotypes with distinct pathophysiological signatures and clinical outcomes may be revealed and support early clinical decision-making. Phenotyping using early vital signs has
Externí odkaz:
https://doaj.org/article/4d1748dd38384169ac5b5f879b2b2fbe
Autor:
Victoria J. Nolan, PhD, Jeremy A. Balch, MD, Naveen P. Baskaran, MD, MSHI, Benjamin Shickel, PhD, Philip A. Efron, MD, FACS, FCCM, Gilbert R. Upchurch, Jr, MD, Azra Bihorac, MD, MS, FCCM, FASN, Christopher J. Tignanelli, MD, MS, FACS, FAMIA, Ray E. Moseley, PhD, Tyler J. Loftus, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 8, p e1131 (2024)
Background:. Surrogates, proxies, and clinicians making shared treatment decisions for patients who have lost decision-making capacity often fail to honor patients’ wishes, due to stress, time pressures, misunderstanding patient values, and project
Externí odkaz:
https://doaj.org/article/9e3b4ebc849f49cab85d6c5ecca4514e
Autor:
Tyler J. Loftus, Jeremy A. Balch, Kenneth L. Abbott, Die Hu, Matthew M. Ruppert, Benjamin Shickel, Tezcan Ozrazgat-Baslanti, Philip A. Efron, Patrick J. Tighe, William R. Hogan, Parisa Rashidi, Michelle I. Cardel, Gilbert R. Upchurch, Azra Bihorac
Publikováno v:
PLOS Digital Health, Vol 3, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/68cd616bf87a42399ad46858a375755d
Autor:
Tyler J. Loftus, MD, Matthew M. Ruppert, MS, Benjamin Shickel, PhD, Tezcan Ozrazgat-Baslanti, PhD, Jeremy A. Balch, MD, Kenneth L. Abbott, MD, Die Hu, MS, Adnan Javed, MD, Firas Madbak, MD, Faheem Guirgis, MD, David Skarupa, MD, Philip A. Efron, MD, Patrick J. Tighe, MD, William R. Hogan, MD, Parisa Rashidi, PhD, Gilbert R. Upchurch, Jr, MD, Azra Bihorac, MD
Publikováno v:
Annals of Surgery Open, Vol 5, Iss 2, p e429 (2024)
Objective:. To determine whether certain patients are vulnerable to errant triage decisions immediately after major surgery and whether there are unique sociodemographic phenotypes within overtriaged and undertriaged cohorts. Background:. In a fair s
Externí odkaz:
https://doaj.org/article/d61e92eec95a4e538b624f9469e1d686
Autor:
Francesca Dal Mas, Lorenzo Cobianchi, Daniele Piccolo, Jeremy Balch, Helena Biancuzzi, Walter L. Biffl, Stefano Campostrini, Enrico Cicuttin, Federico Coccolini, Dimitris Damaskos, Amanda C. Filiberto, Claudia Filisetti, Gustavo Fraga, Simone Frassini, Paola Fugazzola, Timothy Hardcastle, Haytham M. Kaafarani, Yoran Kluger, Maurizio Massaro, Jacopo Martellucci, Ernest Moore, Federico Ruta, Massimo Sartelli, Philip F. Stahel, George Velmahos, Dieter G. Weber, Fausto Catena, Tyler J. Loftus, Luca Ansaloni, the STAR Study Group
Publikováno v:
World Journal of Emergency Surgery, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background The importance of environmental sustainability is acknowledged in all sectors, including healthcare. To meet the United Nations Sustainable Development Goals 2030 Agenda, healthcare will need a paradigm shift toward more environme
Externí odkaz:
https://doaj.org/article/f26cf5ec570b4aa784025a91b1262377
Autor:
Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis engenders distinct host immunologic changes that include the expansion of myeloid-derived suppressor cells (MDSCs). These cells play a physiologic role in tempering acute inflammatory responses but can persist in patients who devel
Externí odkaz:
https://doaj.org/article/c3d9f1e91fd841aa9fdb8d5f4c7a4bf1
Autor:
Jeremy A. Balch, Uan-I Chen, Oliver Liesenfeld, Petr Starostik, Tyler J. Loftus, Philip A. Efron, Scott C. Brakenridge, Timothy E. Sweeney, Lyle L. Moldawer
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-12 (2023)
Abstract Background Sepsis is a heterogenous syndrome with limited therapeutic options. Identifying immunological endotypes through gene expression patterns in septic patients may lead to targeted interventions. We investigated whether patients admit
Externí odkaz:
https://doaj.org/article/ebd16a5d714d405c8c683d468eb7bc5b
Autor:
Jeremy A. Balch, Tyler J. Loftus, Philip A. Efron, Alicia M. Mohr, Gilbert R. Upchurch, R. Stephen Smith
Publikováno v:
World Journal of Emergency Surgery, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Outcomes following aortic occlusion for trauma and hemorrhagic shock are poor, leading some to question the clinical utility of aortic occlusion in this setting. This study evaluates neurologically intact survival following resusc
Externí odkaz:
https://doaj.org/article/cad3cd92bb2144168e4920a326f4897e