Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tyler J. Lieberthal"'
Autor:
Yun Weng, Tyler J. Lieberthal, Vivian X. Zhou, Maya Lopez-Ichikawa, Manuel Armas-Phan, Tristan K. Bond, Miya C. Yoshida, Won-Tak Choi, Tammy T. Chang
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for ma
Externí odkaz:
https://doaj.org/article/0bff35d1afa14287b8227e909f2a2ad1
Autor:
Tatevik, Sahakyants, Tyler J, Lieberthal, Carly D, Comer, Matthew James, Hancock, Andrew P, Spann, Craig M, Neville, Joseph, Vacanti
Publikováno v:
Tissue engineering. Part C, Methods.
This study presents a novel surgical model developed to provide hematological support for implanted cellularized devices augmenting or replacing liver tissue function. Advances in bioengineering provide tools and materials to create living tissue rep
Autor:
Sami Ramadan, Iain E. Dunlop, Norbert Klein, Armando del Río Hernández, C. Watts, Deana Kwong Hong Tsang, Tyler J Lieberthal
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
A graphene field-effect transistor (gFET) was non-covalently functionalised with 1-pyrenebutyric acid N-hydroxysuccinimide ester and conjugated with anti-CD63 antibodies for the label-free detection of exosomes. Using a microfluidic channel, part of
Autor:
Agnes G. Loeffler, John S. Kuo, W. John Kao, Tyler J Lieberthal, Kelli B. Pointer, Jonathan N. Ouellette, Kevin W. Eliceiri, Cole R. Drifka, Yuming Liu
Publikováno v:
Bioengineering
Bioengineering, Vol 8, Iss 17, p 17 (2021)
Bioengineering, Vol 8, Iss 17, p 17 (2021)
Recent research has highlighted the importance of key tumor microenvironment features, notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and progression. This led to great interest from both basic researchers and c
Autor:
Miya C Yoshida, Vivian X. Zhou, Tristan K Bond, Won-Tak Choi, Yun Weng, Tyler J Lieberthal, Tammy T. Chang, Manuel Armas-Phan, Maya Lopez-Ichikawa
Publikováno v:
JCI insight, vol 5, iss 20
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab75cd489d8b7e44b8fc286237f95bb
https://escholarship.org/uc/item/0n16r4rk
https://escholarship.org/uc/item/0n16r4rk
Autor:
Armando del Río Hernández, Dariusz Lachowski, Mariko Okada-Hatakeyama, Ernesto Cortes, Kazunari Iwamoto, Jaakko Teppo, Stephen D. Thorpe, Benjamin Robinson, Muge Sarper, Markku Varjosalo, David A. Lee, Tyler J Lieberthal
Publikováno v:
EMBO Reports
The tumor microenvironment is fundamental to cancer progression, and the influence of its mechanical properties is increasingly being appreciated. Tamoxifen has been used for many years to treat estrogen‐positive breast cancer. Here we report that
Publikováno v:
Journal of Biomedical Materials Research Part A. 103:3772-3780
Polymorphonuclear leukocytes (PMNs) release granule proteins as the first line of defense against bacteria and set up chemotactic gradients that result in monocyte infiltration to the site of injury. Although well established, the role of biomaterial
Publikováno v:
Scientific Reports
The hallmark of pancreatic ductal adenocarcinoma (PDAC) is abundant desmoplasia, which is orchestrated by pancreatic stellate cells (PSCs) and accounts for the majority of the stroma surrounding the tumour. Healthy PSCs are quiescent, but upon activa
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(6)
Talin is a ubiquitous, large focal adhesion protein that links intracellular networks with the extracellular matrix (ECM) via its connection with the actin cytoskeleton and membrane integrins. It is one of a handful molecules that can expose new reco
In the foreign body response, infiltrating PMNs exocytose granule subsets to influence subsequent downstream inflammatory and wound healing events. In previous studies, we found that PMNs cultured on poly(ethylene glycol) (PEG)-containing hydrogels (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0febdee00cc1e260457bf7ad38a3cf
https://europepmc.org/articles/PMC5866922/
https://europepmc.org/articles/PMC5866922/