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pro vyhledávání: '"Tyler J. Bussian"'
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss , Pp 17-25 (2019)
Aging can be defined as the natural process of accumulating time during the life of an organism. Advancing age correlates with tissue dysfunction, including frailty, malignancies, immobility, and cognitive loss. With increasing age, there is an accum
Externí odkaz:
https://doaj.org/article/946cd4592aa64a7aa4eeba2f0da3d899
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss, Pp 17-25 (2019)
Aging can be defined as the natural process of accumulating time during the life of an organism. Advancing age correlates with tissue dysfunction, including frailty, malignancies, immobility, and cognitive loss. With increasing age, there is an accum
Cellular Identification and Quantification of Senescence-Associated β-Galactosidase Activity In Vivo
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989300
Senescence-associated β-galactosidase (hereafter SA-β-gal) staining has now been employed for more than 20 years to identify the presence of senescent cells (Dimri et al., Proc Natl Acad Sci U S A 92:9363-9367, 1995). These cells, characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609c1c063e9b60a9cfb221b6c2e5ef6c
https://doi.org/10.1007/978-1-4939-8931-7_4
https://doi.org/10.1007/978-1-4939-8931-7_4
Autor:
Darren J. Baker, Barbara L. Swenson, Asef Aziz, Jan M. van Deursen, Tyler J. Bussian, Charlton F. Meyer
Publikováno v:
Nature
Nature, 562, 578-582
Nature, 562, 7728, pp. 578-582
Nature, 562, 578-582
Nature, 562, 7728, pp. 578-582
Cellular senescence, which is characterized by an irreversible cell-cycle arrest1 accompanied by a distinctive secretory phenotype2, can be induced through various intracellular and extracellular factors. Senescent cells that express the cell cycle i