Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tyler J, Creamer"'
Autor:
Clayton P. Santiago, PhD, MS, Megan Y. Gimmen, BSc, Yuchen Lu, BSc, Minda M. McNally, MS, Leighton H. Duncan, MA, BSc, Tyler J. Creamer, PhD, Linda D. Orzolek, MS, Seth Blackshaw, PhD, Mandeep S. Singh, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100335- (2023)
Purpose: Proliferative vitreoretinopathy (PVR) is the most common cause of failure of retinal reattachment surgery, and the molecular changes leading to this aberrant wound healing process are currently unknown. Our ultimate goal is to study PVR path
Externí odkaz:
https://doaj.org/article/33c3d0e044e2446db6f33df651349f50
Autor:
Emily E. Bramel, Rustam Bagirzadeh, Muzna Saqib, Tyler J. Creamer, Wendy A. Espinoza Camejo, LaToya Ann Roker, Jennifer Pardo Habashi, Harry C. Dietz, Elena Gallo MacFarlane
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Angiotensin II (Ang II) type 1 receptor (AT1R) signaling controls both physiological and pathogenetic responses in the vasculature. In mouse models of Loeys-Dietz syndrome (LDS), a hereditary disorder characterized by aggressive aortic aneurysms, tre
Externí odkaz:
https://doaj.org/article/d9385657e9684241b2c41f25b1b6385a
Autor:
Emily E. Bramel, Tyler J. Creamer, Muzna Saqib, Wendy A. Camejo Nunez, Rustam Bagirzadeh, LaToya Ann Roker, Loyal A. Goff, Elena Gallo MacFarlane
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how the initial signaling deficiency triggers secondar
Externí odkaz:
https://doaj.org/article/4c3c141c39ab4539a19fe9950090de1a
Autor:
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory J. Konar, Ming-wen Hu, Minda M. McNally, Yu-chen Lu, Miguel Flores-Bellver, Silvia Aparicio-Domingo, Kang V. Li, Zhuo-lin Li, Dzhalal Agakishiev, Sarah E. Hadyniak, Katarzyna A. Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, M. Valeria Canto-Soler, Jiang Qian, Zheng Jiang, Robert J. Johnston, Seth Blackshaw, Mandeep S. Singh
Publikováno v:
Stem Cell Reports. 18:1138-1154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82f9b964ca622ecf3a99f27e8d74a50
https://doi.org/10.1016/j.stemcr.2023.04.004
https://doi.org/10.1016/j.stemcr.2023.04.004
Publikováno v:
Pathology of Genetically Engineered and Other Mutant Mice. :284-306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8be323dc8ebb96313c391e8a4596b44
https://doi.org/10.1002/9781119624608.ch14
https://doi.org/10.1002/9781119624608.ch14
Autor:
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory J. Konar, Ming-wen Hu, Minda M. McNally, Yu-chen Lu, Zhuo-lin Li, Dzhalal Agakishiev, Sarah E. Hadyniak, Katarzyna A. Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, Jiang Qian, Zheng Jiang, Robert J. Johnston, Seth Blackshaw, Mandeep S. Singh
Human retinal organoid transplantation can potentially restore vision in patients with degenerative retinal diseases. How the recipient retina regulates the maturation, fate specification, and migration of transplanted organoid cells is unknown. We t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6b18ec5f2293bc8d030694d288386a
https://doi.org/10.1101/2022.05.12.491655
https://doi.org/10.1101/2022.05.12.491655
Autor:
Emily E. Bramel, Tyler J. Creamer, Muzna Saqib, Wendy A. Camejo Nunez, Rustam Bagirzadeh, LaToya Ann Roker, Loyal A. Goff, Elena Gallo MacFarlane
Publikováno v:
Frontiers in cardiovascular medicine. 9
Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how the initial signaling deficiency triggers secondar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c32d9286a7eb6eb631ec6d959699ff2
https://pubmed.ncbi.nlm.nih.gov/35463747
https://pubmed.ncbi.nlm.nih.gov/35463747
Autor:
Emily E Bramel, Tyler J Creamer, Muzna Saqib, Wendy A Camejo Nunez, Loyal A Goff, Elena Gallo MacFarlane
Publikováno v:
Circulation. 144
The pathogenesis of aortic aneurysms caused by mutations that impair TGF-β/Smad signaling without completely ablating it remains unclear. To investigate TGF-β’s role independently of its developmental functions, we used mouse models to inactivate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1660297112a422e16176aa3e9d7a3687
https://doi.org/10.1161/circ.144.suppl_1.11068
https://doi.org/10.1161/circ.144.suppl_1.11068
Autor:
Matthew K Knabel, Kalyani Ramachandran, Sunil Karhadkar, Hun-Way Hwang, Tyler J Creamer, Raghu R Chivukula, Farooq Sheikh, K Reed Clark, Michael Torbenson, Robert A Montgomery, Andrew M Cameron, Joshua T Mendell, Daniel S Warren
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124411 (2015)
Fibrosis refers to the accumulation of excess extracellular matrix (ECM) components and represents a key feature of many chronic inflammatory diseases. Unfortunately, no currently available treatments specifically target this important pathogenic mec
Externí odkaz:
https://doaj.org/article/bf6c1ba14f9d47e3a0e601227e9b4504
Autor:
Tyler J Creamer, Miranda M Darby, Nuttara Jamonnak, Paul Schaughency, Haiping Hao, Sarah J Wheelan, Jeffry L Corden
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002329 (2011)
RNA polymerase II synthesizes a diverse set of transcripts including both protein-coding and non-coding RNAs. One major difference between these two classes of transcripts is the mechanism of termination. Messenger RNA transcripts terminate downstrea
Externí odkaz:
https://doaj.org/article/23f12664d9b44cf19a27a4398d502aed