Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tyler E. Benedum"'
Autor:
Nathaniel Lim, Michael D. Devous, Michael Case, Mark A. Mintun, Andrew Siderowf, Ming Lu, Caitlin Pearson, Eric Siemers, Tyler E. Benedum, Marybeth Devine, Mark Lowrey, Karen Sundell, Michael J. Pontecorvo, Abhinay D. Joshi, Sudeepti Southekal
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Nathaniel Lim, Seok Rye Choi, Franz Hefti, Tyler E. Benedum, Michael R. Kilbourn, Geoff Golding, Daniel Skovronsky, Hank F. Kung, Zhi-Ping Zhuang, Wei Zhang
Publikováno v:
Journal of Nuclear Medicine. 50:1887-1894
beta-amyloid plaques (Abeta plaques) in the brain, containing predominantly fibrillary Abeta peptide aggregates, represent a defining pathologic feature of Alzheimer disease (AD). Imaging agents targeting the Abeta plaques in the living human brain a
Publikováno v:
Tetrahedron Letters. 46:4677-4681
A study investigating the structural features directing olefin cross-metathesis to afford C-glycoamino acids was carried out. These results lead to an appreciation of the importance of proximal functionality to the relative reactivity of olefins in m
Publikováno v:
Tetrahedron Letters. 44:3775-3779
As part of efforts to make available new classes of bioactive C-glycoconjugates, d -glucosamine has been effectively converted into a series of 2-deoxy-2-amino-C-glycosides. This versatile approach is keyed by a remarkably effective metal catalyzed o
Publikováno v:
Organic Letters. 4:3591-3594
[reaction: see text] The synthesis of stable, C-linked analogues of glycopeptides is being investigated with two complementary synthetic strategies, co-translational and post-translational glycopeptide synthesis. The key feature of the present approa
Publikováno v:
Organic Letters. 6:3593-3595
[reaction: see text] 2,5-disubstituted and 2,4,5-trisubstituted oxazol-5-yl carbonyl compounds were prepared in good yields by a mild SiO2-mediated cycloisomerization of propargyl amides.
Publikováno v:
Journal of medicinal chemistry. 50(9)
We report a series of radioiodinated styrylpyridines as single photon emission computed tomography probes for imaging Abeta plaques in the brain of patients with Alzheimer's disease (AD). In vitro binding showed that all of the styrylpyridines displa
Publikováno v:
European Journal of Nuclear Medicine & Molecular Imaging. Oct2011, Vol. 38, pS86-S463. 378p.
Publikováno v:
European Journal of Nuclear Medicine & Molecular Imaging. Oct2011, Vol. 38, p229-259. 31p.