Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tyler E Papp"'
Autor:
Hamideh Parhiz, Vladimir V. Shuvaev, Qin Li, Tyler E. Papp, Awurama A. Akyianu, Ruiqi Shi, Amir Yadegari, Hamna Shahnawaz, Sean C. Semple, Barbara L. Mui, Drew Weissman, Vladimir R. Muzykantov, Patrick M. Glassman
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102175- (2024)
RNA therapeutics are an emerging, powerful class of drugs with potential applications in a wide range of disorders. A central challenge in their development is the lack of clear pharmacokinetic (PK)-pharmacodynamic relationship, in part due to the si
Externí odkaz:
https://doaj.org/article/7f789f117b494a00a874576d1146347e
Autor:
Tyler E Papp, Hamideh Parhiz, Jesse L Rodriguez, Logan Zhang, Kelly A Hicks, Zev Binder, Donald O’Rourke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2d37bd4b9a77484da10245646021105e
Autor:
Adrian Bot, Steven M Albelda, Tyler E Papp, Caitlin M Tilsed, Barzan A Sadiq, Phurin Areesawangkit, Estela Noguera-Ortega, Kenji Kimura, Nicholas Cerda, Haig Aghajanian, Barbara Mui, Ying Tam, Drew Weissman, Hamideh Parhiz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f206ede59c654db8a8076df93c903be8
Autor:
Devin S. McDougald, Thu T. Duong, Katherine C. Palozola, Anson Marsh, Tyler E. Papp, Jason A. Mills, Shangzhen Zhou, Jean Bennett
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 380-389 (2019)
Validation of gene transfer vectors containing tissue-specific promoters in cell-based functional assays poses a formidable challenge for gene therapy product development. Here, we describe a novel approach based on CRISPR/dCas9 transcriptional activ
Externí odkaz:
https://doaj.org/article/a7e32489c3ba424391379c4ed1370078
Autor:
Maxwell Chappell, Laura Breda, Danuta Jadwiga Jarocha, Michael Triebwasser, Tyler E Papp, Valentina Ghiaccio, Megan T Fedorky, Amaliris Guerra, Kandace Gollomp, Osheiza Y. Abdulmalik, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Hamideh Parhiz, Stefano Rivella
Publikováno v:
Blood. 140:300-302
Autor:
Hamideh Parhiz, Jacob S. Brenner, Priyal N. Patel, Tyler E. Papp, Hamna Shahnawaz, Qin Li, Ruiqi Shi, Marco E. Zamora, Amir Yadegari, Oscar A. Marcos-Contreras, Ambika Natesan, Norbert Pardi, Vladimir V. Shuvaev, Raisa Kiseleva, Jacob W. Myerson, Thomas Uhler, Rachel S. Riley, Xuexiang Han, Michael J. Mitchell, Kieu Lam, James Heyes, Drew Weissman, Vladimir R. Muzykantov
Publikováno v:
Journal of Controlled Release
Current nucleoside-modified RNA lipid nanoparticle (modmRNA-LNP) technology has successfully paved the way for the highest clinical efficacy data from next-generation vaccinations against SARS-CoV-2 during the COVID-19 pandemic. However, such modmRNA
Autor:
Joel G. Rurik, István Tombácz, Amir Yadegari, Pedro O. Méndez Fernández, Swapnil V. Shewale, Li Li, Toru Kimura, Ousamah Younoss Soliman, Tyler E. Papp, Ying K. Tam, Barbara L. Mui, Steven M. Albelda, Ellen Puré, Carl H. June, Haig Aghajanian, Drew Weissman, Hamideh Parhiz, Jonathan A. Epstein
Publikováno v:
Science. 375:91-96
Making CAR T cells in vivo Cardiac fibrosis is the stiffening and scarring of heart tissue and can be fatal. Rurik et al . designed an immunotherapy strategy to generate transient chimeric antigen receptor (CAR) T cells that can recognize the fibroti
Autor:
Joel G. Rurik, István Tombácz, Amir Yadegari, Pedro O. Méndez Fernández, Swapnil V. Shewale, Li Li, Toru Kimura, Ousamah Younoss Soliman, Tyler E. Papp, Ying K. Tam, Barbara L. Mui, Steven M. Albelda, Ellen Puré, Carl H. June, Haig Aghajanian, Drew Weissman, Hamideh Parhiz, Jonathan A. Epstein
Publikováno v:
Diagnostic and Treatment Advances in COVID-19 and SARS-CoV-2 ISBN: 9788119039630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b33f294e686f1fe4dd886f4284b016
https://doi.org/10.9734/bpi/mono/978-81-19039-63-0/ch19
https://doi.org/10.9734/bpi/mono/978-81-19039-63-0/ch19
Autor:
Laura Breda, Tyler E Papp, Michael Triebwasser, Amir Yadegari, Megan T Fedorky, Naoto Tanaka, Houping Ni, Drew Weissman, Stefano Rivella, Hamideh Parhiz
Publikováno v:
Blood. 140:305-306
Publikováno v:
Mol Ther
Mutations within over 250 known genes are associated with inherited retinal degeneration. Clinical success following gene-replacement therapy for congenital blindness due to RPE65 mutations establishes a platform for the development of downstream tre