Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Tyler E, Miller"'
Autor:
Tyler E Miller, Mario Suva, Zeyu Chen, Chadi El Farran, Charles Couturier, Joshua D’Antonio, Alex Shalek, Kevin Petrecca, Bradley Bernstein
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/db1f252b79d74e5f97e5aaed116ab724
Autor:
David J. Gregory, Augustin Vannier, Akiro H. Duey, Tyler J. Roady, Richard K. Dzeng, Maia N. Pavlovic, Michael H. Chapin, Sonia Mukherjee, Hannah Wilmot, Nic Chronos, Richelle C. Charles, Edward T. Ryan, Regina C. LaRocque, Tyler E. Miller, Wilfredo F. Garcia-Beltran, Julia C. Thierauf, A. John Iafrate, Steven Mullenbrock, Mark D. Stump, Randall K. Wetzel, Roberto D. Polakiewicz, Vivek Naranbhai, Mark C. Poznansky
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 890-902 (2022)
Antibodies to SARS-CoV-2 are central to recovery and immunity from COVID-19. However, the relationship between disease severity and the repertoire of antibodies against specific SARS-CoV-2 epitopes an individual develops following exposure remains in
Externí odkaz:
https://doaj.org/article/e0d631b0eef044d7b1cd22855041802d
Autor:
Tyler E Miller, Tyler Brown, Yonatan Grad, Satchit Balsari, Keith Johnson, Jochen Lennerz, Julia Thierauf, James S Miller, Pablo Martinez de Salazar Munoz, Abhishek Bhatia, Bridget Bunda, Ellen K Williams, David Bor, Amir Mohareb, Wenxin Yang, Julian Villalba, Vivek Naranbai, Wilfredo Garcia Beltran, Doug Kress, Kristen Stelljes, Dan Larremore, A John Iafrate, Caroline Buckee
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Objectives Convenience sampling is an imperfect but important tool for seroprevalence studies. For COVID-19, local geographic variation in cases or vaccination can confound studies that rely on the geographically skewed recruitment inherent to conven
Externí odkaz:
https://doaj.org/article/fda6128353b1463d8f5a757bb9435891
Autor:
Christopher Hubert, Kelly Mitchell, Samuel Sprowls, Sajina Shakya, Sonali Arora, Daniel J. Silver, Christopher M. Goins, Lisa Wallace, Gustavo Roversi, Rachel Schafer, Kristen Kay, Tyler E. Miller, Adam Lauko, John Bassett, Anjali Kashyap, J. D’Amato Kass, Erin E. Mulkearns-Hubert, Sadie Johnson, Joseph Alvarado, Jeremy N. Rich, Patrick J. Paddison, Anoop P. Patel, Shaun R. Stauffer, Christopher G. Hubert, Justin D. Lathia
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 107-107 (2023)
OBJECTIVES/GOALS: Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors that are driven by populations of cancer stem cells (CSCs). In this study, we perform an epigenetic-focused functional genomics screen in GBM organoids and identify
Externí odkaz:
https://doaj.org/article/38b0f34846504b9fac37c7e24f076612
Autor:
Kelly Mitchell, Samuel A. Sprowls, Sonali Arora, Sajina Shakya, Daniel J. Silver, Christopher M. Goins, Lisa Wallace, Gustavo Roversi, Rachel E. Schafer, Kristen Kay, Tyler E. Miller, Adam Lauko, John Bassett, Anjali Kashyap, Jonathan D'Amato Kass, Erin E. Mulkearns-Hubert, Sadie Johnson, Joseph Alvarado, Jeremy N. Rich, Eric C. Holland, Patrick J. Paddison, Anoop P. Patel, Shaun R. Stauffer, Christopher G. Hubert, Justin D. Lathia
Publikováno v:
Genes & Development. 37:86-102
Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors driven by populations of cancer stem cells (CSCs). However, few molecular mechanisms critical for CSC population maintenance have been exploited for therapeutic development. We develo
Autor:
Matthew S. Elitt, H. Elizabeth Shick, Mayur Madhavan, Kevin C. Allan, Benjamin L.L. Clayton, Chen Weng, Tyler E. Miller, Daniel C. Factor, Lilianne Barbar, Baraa S. Nawash, Zachary S. Nevin, Angela M. Lager, Yan Li, Fulai Jin, Drew J. Adams, Paul J. Tesar
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 711-726 (2018)
Summary: Pelizaeus-Merzbacher disease (PMD) is a fatal X-linked disorder caused by loss of myelinating oligodendrocytes and consequent hypomyelination. The underlying cellular and molecular dysfunctions are not fully defined, but therapeutic enhancem
Externí odkaz:
https://doaj.org/article/85ceab688bb44f7d8336a4d35cb11973
Autor:
Michael M. Lizardo, James J. Morrow, Tyler E. Miller, Ellen S. Hong, Ling Ren, Arnulfo Mendoza, Charles H. Halsey, Peter C. Scacheri, Lee J. Helman, Chand Khanna
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 11, Pp 699-710 (2016)
Metastasis is the cause of more than 90% of all cancer deaths. Despite this fact, most anticancer therapeutics currently in clinical use have limited efficacy in treating established metastases. Here, we identify the endoplasmic reticulum chaperone p
Externí odkaz:
https://doaj.org/article/1cec0555a1e7493ba110c2223f943639
Autor:
Jeremy N. Rich, Shideng Bao, Vaidehi Mahadev, Zhe Zhu, Xiaoguang Fang, Wenchao Zhou, Zhen Dong, Anne Song, Christopher G. Hubert, Tyler E. Miller, Qi Xie, Sisi Lai, Yu Shi, Ryan C. Gimple, Leo J.Y. Kim, Kailin Yang, Stephen C. Mack, Briana C. Prager, Qiulian Wu, Zhi Huang, Xiuxing Wang
Supplementary Figure 1. Induction of differentiation by BMP4 decreased expression of mevalonate synthesis enzymes (HMGCR, PMVK, MVK, MVD, IDI1 and FDPS). Supplementary Figure 2. Gene expression data from TCGA GBM patients revealed a high degree of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d85ae70ac580cd0715de5dd0a9749e
https://doi.org/10.1158/0008-5472.22415327
https://doi.org/10.1158/0008-5472.22415327
Autor:
Jeremy N. Rich, Shideng Bao, Vaidehi Mahadev, Zhe Zhu, Xiaoguang Fang, Wenchao Zhou, Zhen Dong, Anne Song, Christopher G. Hubert, Tyler E. Miller, Qi Xie, Sisi Lai, Yu Shi, Ryan C. Gimple, Leo J.Y. Kim, Kailin Yang, Stephen C. Mack, Briana C. Prager, Qiulian Wu, Zhi Huang, Xiuxing Wang
Metabolic dysregulation drives tumor initiation in a subset of glioblastomas harboring isocitrate dehydrogenase (IDH) mutations, but metabolic alterations in glioblastomas with wild-type IDH are poorly understood. MYC promotes metabolic reprogramming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d28074287457937279e96705b14f945
https://doi.org/10.1158/0008-5472.c.6509234.v1
https://doi.org/10.1158/0008-5472.c.6509234.v1
Autor:
Kevin C. Allan, Tyler E. Miller, Andrew R. Morton, Marissa A. Scavuzzo, Matthew S. Elitt, Benjamin L.L. Clayton, Lucille R. Hu, Jost K. Vrabic, Hannah E. Olsen, Daniel C. Factor, Jonathan E. Henninger, Richard A. Young, Charles Y. Lin, Peter C. Scacheri, Paul J. Tesar
SUMMARYPluripotent stem cells (PSCs) provide an unlimited source for generating somatic cell types. However, generating fully mature cells constitutes a bottleneck for realizing their full potential in research and medicine. Here, we report a transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee17af1d86d3aea0ee785bea3821dc2
https://doi.org/10.1101/2022.11.17.516981
https://doi.org/10.1101/2022.11.17.516981