Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tyler Duellman"'
Autor:
Patrick R. Carney, Tyler Duellman, Jia-Yi Chan, Lauren Wells, Michael Tessmer, Leah Frater-Rubsam, Molly Zeller, Mark Field, James Speers, Kelly Tyrrell, Luke Thompson, Michael Bondurant, Tami Morin, Tamra Dagnon, Brian Goff, Corissa Runde, Sandra Splinter-Bondurant, Charles Konsitzke, Patrick Kelly, Christopher A. Bradfield, Joshua Hyman
Publikováno v:
COVID, Vol 3, Iss 7, Pp 1031-1041 (2023)
The COVID-19 pandemic necessitated sensitive, fast, and inexpensive testing for the virus in 2020 prior to the widespread availability of vaccines. Early testing efforts were limited by bottlenecks on reagents, low-throughput testing options, and the
Externí odkaz:
https://doaj.org/article/2bbeb3cd6ea54c23b99c65fb41319cdd
Publikováno v:
Metalloproteinases in medicine
Tyler Duellman, Andrea Doll, Xi Chen, Rie Wakamiya, Jay YangDepartment of Anesthesiology, University of Wisconsin SMPH, Madison, WI, USAAbstract: Selective gene activation with the dCas9 (deactivated clustered regularly interspaced short palindromic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0051695a4b3e936f7ad40638d4d2264d
https://doi.org/10.2147/mnm.s146752
https://doi.org/10.2147/mnm.s146752
Autor:
Hung Tae Kim, Miles L. Epstein, Bazbek Davletov, Jay Yang, Charlotte Leese, Tyler Duellman, Timur A. Mavlyutov
Publikováno v:
Neuroscience. 331:148-157
Sigma-1 receptor (S1R) is a unique pluripotent modulator of living systems and has been reported to be associated with a number of neurological diseases including pathological pain. Intrathecal administration of S1R antagonists attenuates the pain be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3320f0692bb979e4dbfa6bef1d44d210
https://doi.org/10.1016/j.neuroscience.2016.06.030
https://doi.org/10.1016/j.neuroscience.2016.06.030
Publikováno v:
Biochemical Journal
Matrix metalloproteinases (MMPs) play varied roles in normal biology and diseases where, depending on the context, both inhibition and enhancement of the enzymatic activity may be beneficial. However, there are very few reports of positive modulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6634a88a7b82a2985ed730e3cde1cb73
https://pubmed.ncbi.nlm.nih.gov/29654109
https://pubmed.ncbi.nlm.nih.gov/29654109
Publikováno v:
Physiology & behavior
The weight-bearing test is one method to assess pain in rodent animal models; however, the acceptance of this convenient method is limited by the low throughput data acquisition and necessity of confining the rodents to a small chamber. New methods W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4b96373d11bd005523d3ffbbd141ef
https://doi.org/10.1016/j.physbeh.2015.06.035
https://doi.org/10.1016/j.physbeh.2015.06.035
Publikováno v:
Traffic. 16:1108-1126
Matrix metalloproteinase-9 (MMP-9) is a secreted endoproteinase with a critical role in the regulation of the extracellular matrix and proteolytic activation of signaling molecules. Human (h)MMP-9 has two well-defined N-glycosylation sites at residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f666886b8dbee484f928bc38c94cb223
https://doi.org/10.1111/tra.12312
https://doi.org/10.1111/tra.12312
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1850:1415-1425
Background Statins are potent inhibitors of cholesterol biosynthesis and are clinically beneficial in preventing cardiovascular diseases, however, the therapeutic utility of these drugs is limited by myotoxicity. Here, we explored the mechanism of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5335ccdd69814d4577e98840680995e9
https://doi.org/10.1016/j.bbagen.2015.03.011
https://doi.org/10.1016/j.bbagen.2015.03.011
Autor:
Raghu Vemuganti, Andrew Crowell, Tyler Duellman, Dominic T. Schomberg, Daniel K. Resnick, Gurwattan S. Miranpuri
Publikováno v:
Metabolic Brain Disease. 30:645-658
Neuropathic pain, especially that resulting from spinal cord injury, is a tremendous clinical challenge. A myriad of biological changes have been implicated in producing these pain states including cellular interactions, extracellular proteins, ion c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94c9f81b5e785b27b1f5936d6e38907
https://doi.org/10.1007/s11011-014-9642-0
https://doi.org/10.1007/s11011-014-9642-0
Publikováno v:
Nucleic Acids Research
Microribonucleic acids (miRNAs) work with exquisite specificity and are able to distinguish a target from a non-target based on a single nucleotide mismatch in the core nucleotide domain. We questioned whether miRNA regulation of gene expression coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064d42e804abe5b61e2aa5356919f439
https://doi.org/10.1093/nar/gku197
https://doi.org/10.1093/nar/gku197
Publikováno v:
Biochemical and biophysical research communications. 464(3)
Matrix metalloproteinase-9 (MMP-9) is a secreted glycoprotein with a major role in shaping the extra-cellular matrix and a detailed understanding of the secretory mechanism could help identify methods to correct diseases resulting from dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41527c9960c8c7883ddc513661cf97f
https://pubmed.ncbi.nlm.nih.gov/26150355
https://pubmed.ncbi.nlm.nih.gov/26150355