Výsledky vyhledávání - "Tyler D. Noble"

Zebrafish Rif1 impacts zygotic genome activation, replication timing, and sex determination

Autor: Emily A. Masser, Tyler D. Noble, Joseph C. Siefert, Duane Goins, Courtney G. Sansam, Christopher L. Sansam

Deregulated DNA replication causes human developmental disorders and cancer, but we know little about how DNA replication is coordinated with changes in transcription and chromatin structure. The initiation of replication forks follows a spatiotempor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752060fdae14d326319a30632943a2db
https://doi.org/10.1101/2022.10.21.512903

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The CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase

Autor: Tyler D Noble, Duane Goins, Courtney G. Sansam, Kimberlie A Wittig, Christopher L. Sansam

Publikováno v: Nucleic Acids Research

A DNA replication program, which ensures that the genome is accurately and wholly replicated, is established during G1, before the onset of S phase. In G1, replication origins are licensed, and upon S phase entry, a subset of these will form active r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cee96092858cafb3c46b83b87fe37e0
https://pubmed.ncbi.nlm.nih.gov/34534348

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