Výsledky vyhledávání - "Tyler Bagué"

YAP/TAZ inactivation with simvastatin attenuates glucocorticoid-induced human trabecular meshwork cell dysfunction

Autor: Hannah Yoo, Ayushi Singh, Haiyan Li, Ana N. Strat, Tyler Bagué, Preethi S. Ganapathy, Samuel Herberg

PurposeImpairment of the trabecular meshwork (TM) is the principal cause of increased outflow resistance in the glaucomatous eye. Yes-associated protein (YAP) and transcriptional coactivator with PDZ binding motif (TAZ) are emerging as potential medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed82d54d673bb67b762d3ce2d9032c32
https://doi.org/10.1101/2022.09.27.509788

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Effects of Netarsudil-Family Rho Kinase Inhibitors on Human Trabecular Meshwork Cell Contractility and Actin Remodeling Using a Bioengineered ECM Hydrogel

Autor: Tyler Bagué, Ayushi Singh, Rajanya Ghosh, Hannah Yoo, Curtis Kelly, Mitchell A. deLong, Casey C. Kopczynski, Samuel Herberg

Publikováno v: Frontiers in Ophthalmology. 2

Interactions between trabecular meshwork (TM) cells and their extracellular matrix (ECM) are critical for normal outflow function in the healthy eye. Multifactorial dysregulation of the TM is the principal cause of elevated intraocular pressure that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bd9949087ee39bb040adf3bb33d75c
https://doi.org/10.3389/fopht.2022.948397

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