Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tyler B. Moran"'
Autor:
Juan Carlos Plana, Tyler B. Moran
Publikováno v:
Current Cardiology Reports. 22
Cancer patients with acute coronary syndrome (ACS) have significantly greater mortality compared with non-cancer patients. This risk is partly directly attributable to the malignancy; however these patients are frequently undertreated with respect to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1cee48b018e1880d4479b44a1a46d2
https://doi.org/10.1007/s11886-020-01409-8
https://doi.org/10.1007/s11886-020-01409-8
Autor:
Ernest Fraenkel, Andrew J. Woo, Ichiro Taniuchi, Carla F. Kim, Alan B. Cantor, Candace R. Chouinard, Hui Huang, Tali Mazor, Robert G. Roeder, Tyler B. Moran, Adam Labadorf, Sima Zacharek, Hsuan-Ting Huang, Ming Yu, Huafeng Xie, Thomas E. Akie, Katie L. Kathrein, Leonard I. Zon
Publikováno v:
Molecular Cell. 45:330-343
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian cells remain incompletely understood. In this study we show that Bmi1, a core component of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e550bcff4016b32403c3c2f8b328f5de
https://doi.org/10.1016/j.molcel.2011.11.032
https://doi.org/10.1016/j.molcel.2011.11.032
Publikováno v:
Molecular Endocrinology. 25:117-127
The pituitary gland contains six distinct hormone-secreting cell types that are essential for basic physiological processes including fertility and responding to stress. Formation of hormone-secreting cells during development relies on Notch signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd6f030bb310ff9c3bc15f717d13445
https://doi.org/10.1210/me.2010-0248
https://doi.org/10.1210/me.2010-0248
Autor:
Laura Riva, Ernest Fraenkel, Yong Cheng, Huafeng Xie, Mitchell J. Weiss, Stuart H. Orkin, Alan B. Cantor, Bradley E. Bernstein, Duonan Yu, Yocheved Schindler, Tyler B. Moran, Ming Yu, Ross C. Hardison
Publikováno v:
Molecular Cell. 36(4):682-695
The transcription factor GATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context. Yet its in vivo site selectivity and ability to distinguish between activated versus repressed genes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c328a765ac12f915d0c9f827a6de09d8
Autor:
Koichi Akashi, Stuart H. Orkin, Hirokazu Shigematsu, Tyler B. Moran, Alan B. Cantor, Yojiro Arinobu, Matthew R. Sullivan, Hiromi Iwasaki
Publikováno v:
The Journal of Experimental Medicine
The zinc finger transcription factor GATA-1 requires direct physical interaction with the cofactor friend of GATA-1 (FOG-1) for its essential role in erythroid and megakaryocytic development. We show that in the mast cell lineage, GATA-1 functions co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce17e9928e71a2bbb2cf9e3088c93ec
https://doi.org/10.1084/jem.20070544
https://doi.org/10.1084/jem.20070544
Publikováno v:
Toxicology and applied pharmacology. 265(1)
Pituitary tumors account for 15% of intracranial neoplasms, however the extent to which environmental toxicants contribute to the proliferation and hormone expression of pituitary cells is unknown. Aryl-hydrocarbon receptor (AhR) interacting protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad2f1009f2122e381c0ed7e4f879664
https://pubmed.ncbi.nlm.nih.gov/22975028
https://pubmed.ncbi.nlm.nih.gov/22975028
Autor:
Andrew J. Woo, Helen He Zhu, Zachary Waldon, Gen-Sheng Feng, Alan B. Cantor, Tyler B. Moran, Hanno Steen, Hui Huang, Yocheved Schindler
Publikováno v:
Genesdevelopment. 26(14)
Hematopoietic development occurs in complex microenvironments and is influenced by key signaling events. Yet how these pathways communicate with master hematopoietic transcription factors to coordinate differentiation remains incompletely understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b1e45dd68b638581507a4da9af4b32
https://pubmed.ncbi.nlm.nih.gov/22802526
https://pubmed.ncbi.nlm.nih.gov/22802526
Autor:
Karl Hsu, Ebrahim Shafizadeh, Tyler B. Moran, Barry H. Paw, Jeffrey D. Cooney, John P. Kanki, Robert I. Handin, Gabriele E. Ackermann, Nathaniel B. Langer, George C. Shaw, David Traver, Yi Zhou, Bruce A. Barut, Wyatt Horsely, Hui Feng Lin, Dongdong Ma, Nikolaus S. Trede, Dhvanit I. Shah, Sarah A. Wojiski, George Kourkoulis, Alan B. Cantor, Julio D. Amigo, Alan J. Davidson, Ming Yu, John J. Cope
Publikováno v:
Blood. 114(21)
The nuclear protein FOG-1 binds transcription factor GATA-1 to facilitate erythroid and megakaryocytic maturation. However, little is known about the function of FOG-1 during myeloid and lymphoid development or how FOG-1 expression is regulated in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b939d032343045e0cc0512e175344154
https://pubmed.ncbi.nlm.nih.gov/19729519
https://pubmed.ncbi.nlm.nih.gov/19729519
Autor:
Andrew J. Woo, Nathan Tu, Alan B. Cantor, Hui Huang, Hanno Steen, Yin Yin Lin, Zachary Waldon, Thomas E. Akie, Tyler B. Moran, Ming Yu
Publikováno v:
Molecular and cellular biology. 29(15)
The transcription factor RUNX-1 plays a key role in megakaryocyte differentiation and is mutated in cases of myelodysplastic syndrome and leukemia. In this study, we purified RUNX-1-containing multiprotein complexes from phorbol ester-induced L8057 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7cb1ba676433f29504791cc4fa5f32
https://pubmed.ncbi.nlm.nih.gov/19470763
https://pubmed.ncbi.nlm.nih.gov/19470763
Autor:
Yuko Fujiwara, Andrew J. Woo, Tyler B. Moran, Alan B. Cantor, Matthew R. Sullivan, Nathaniel B. Langer, Seong-Kyu Choe, Barry H. Paw, Yocheved Schindler
Publikováno v:
Molecular and cellular biology. 28(8)
A complete understanding of the transcriptional regulation of developmental lineages requires that all relevant factors be identified. Here, we have taken a proteomic approach to identify novel proteins associated with GATA-1, a lineage-restricted zi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67bc8def743b5197cae565f35c03b23
https://pubmed.ncbi.nlm.nih.gov/18250154
https://pubmed.ncbi.nlm.nih.gov/18250154