Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tyler B. Krause"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 376-386 (2020)
Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lac
Externí odkaz:
https://doaj.org/article/a01a18cf1729403a9a933268be62fc27
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT Ebola virus (EBOV) makes extensive and intricate use of host factors in the cellular endosomal/lysosomal pathway to release its genome into the cytoplasm and initiate infection. Following viral internalization into endosomes, host cysteine p
Externí odkaz:
https://doaj.org/article/c1924e971692459c8bf93cc724298d57
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 376-386 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lac
Autor:
Kristian G. Andersen, Douglas A. Lauffenburger, Tyler B. Krause, Larry Zeitlin, Yoshihiro Kawaoka, Wen-Han Yu, Peter Halfmann, Erica Ollmann Saphire, Marnie L. Fusco, Xiangguo Qiu, Sharon L. Schendel, Jishnu Das, John M. Dye, Shinhua He, Bronwyn M. Gunn, Marcus M. Karim, Gary P. Kobinger, Jennifer M. Brannan, Anna Z. Wec, Galit Alter, Kartik Chandran, Andrew S. Herbert, Jonathan R. Lai, Todd J. Suscovich, James E. Crowe, Karthik Gangavarapu
Publikováno v:
PMC
The recent Ebola virus (EBOV) epidemic highlighted the need for effective vaccines and therapeutics to limit and prevent outbreaks. Host antibodies against EBOV are critical for controlling disease, and recombinant monoclonal antibodies (mAbs) can pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0578ded86da5b9c683e918ebfa6b105a
https://europepmc.org/articles/PMC6298217/
https://europepmc.org/articles/PMC6298217/
Autor:
Christopher J. Schulze, Ariel A. Wirchnianski, Matthew Bogyo, Tyler B. Krause, John M. Dye, Wouter A. van der Linden, Kartik Chandran, Andrew S. Herbert
Publikováno v:
ACS infectious diseases. 2(3)
The recent Ebola virus outbreak in western Africa highlights the need for novel therapeutics that target Ebola virus and other filoviruses. Filoviruses require processing by host cell-derived cysteine cathepsins for productive infection. Here we repo
Publikováno v:
mBio, Vol 7, Iss 1, p e01857-15 (2016)
mBio
mBio, Vol 7, Iss 1 (2016)
mBio
mBio, Vol 7, Iss 1 (2016)
Ebola virus (EBOV) makes extensive and intricate use of host factors in the cellular endosomal/lysosomal pathway to release its genome into the cytoplasm and initiate infection. Following viral internalization into endosomes, host cysteine proteases
Autor:
Kshitiji Wagh, Hannah L. Turner, M. Javad Aman, Alain Townsend, George Georgiou, Florian Krammer, Christos A. Kyratsous, Andrew B. Ward, Laura M. Walker, Michael H. Pauly, Viktor E. Volchkov, Peter Halfmann, Bette T. Korber, James E. Crowe, Shihua He, Jesper Pallesen, Alexander Bukreyev, Pramila Rijal, Edgar Davidson, Bronwyn M. Gunn, Charles D. Murin, Jonathan R. Lai, Ayato Takada, Dennis R. Burton, Anna Z. Wec, Gary P. Kobinger, Benjamin J. Doranz, Rafi Ahmed, Erica Ollmann Saphire, Xiangguo Qiu, Carl W. Davis, Tyler B. Krause, Kathleen B. J. Pommert, Cory Nykiforuk, Yoshihiro Kawaoka, Sharon L. Schendel, John M. Dye, Elena E. Giorgi, Karthik Gangavarapu, James Theiler, Larry Zeitlin, Marnie L. Fusco, Kristian G. Andersen, Cheng-I Wang, Jennifer M. Brannan, Andrew S. Herbert, Galit Alter, Kartik Chandran
Publikováno v:
Cell. 174:938-952.e13
Antibodies are promising post-exposure therapies against emerging viruses, but which antibody features and in vitro assays best forecast protection are unclear. Our international consortium systematically evaluated antibodies against Ebola virus (EBO
Autor:
Kevin R. Patrick, Geoffrey M. Attardo, Joshua B. Benoit, Serap Aksoy, Guangxiao Yang, Tyler B. Krause
During pregnancy in the viviparous tsetse fly, lipid mobilization is essential for the production of milk to feed the developing intrauterine larva. Lipophorin (Lp) functions as the major lipid transport protein in insects and closely-related arthrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff09a7edf23f134cb4b1ea5022fc07a
https://europepmc.org/articles/PMC3209505/
https://europepmc.org/articles/PMC3209505/
Autor:
Zachary P. Phillips, Kevin R. Patrick, Joshua B. Benoit, David L. Denlinger, Tyler B. Krause, Giancarlo Lopez-Martinez
The mosquito's body temperature increases dramatically when it takes a blood meal from a warm-blooded, vertebrate host. By using the yellow fever mosquito, Aedes aegypti , we demonstrate that this boost in temperature following a blood meal prompts t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8043cc78cacea9d8dd43f70786100d
https://europepmc.org/articles/PMC3093486/
https://europepmc.org/articles/PMC3093486/
Autor:
Serap Aksoy, David L. Denlinger, Paul O. Mireji, Geoffrey M. Attardo, Veronika Michalkova, Peter Takac, Qirui Zhang, José M. C. Ribeiro, Aaron A. Baumann, Tyler B. Krause, Joshua B. Benoit, Jana Bohova
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1003874 (2014)
PLoS Genetics
PLoS genetics, vol 10, iss 4
PLoS Genetics
PLoS genetics, vol 10, iss 4
In tsetse flies, nutrients for intrauterine larval development are synthesized by the modified accessory gland (milk gland) and provided in mother's milk during lactation. Interference with at least two milk proteins has been shown to extend larval d