Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tyler A Sisley"'
Autor:
Irina Shlosman, Elayne M. Fivenson, Morgan S. A. Gilman, Tyler A. Sisley, Suzanne Walker, Thomas G. Bernhardt, Andrew C. Kruse, Joseph J. Loparo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The peptidoglycan (PG) cell wall protects bacteria against osmotic lysis and determines cell shape, making this structure a key antibiotic target. Peptidoglycan is a polymer of glycan chains connected by peptide crosslinks, and its synthesis
Externí odkaz:
https://doaj.org/article/46f4aabe611d4823be2a46c4d4c0f829
Autor:
Thomas M. Bartlett, Tyler A. Sisley, Aaron Mychack, Suzanne Walker, Richard W. Baker, David Z. Rudner, Thomas G. Bernhardt
SUMMARYStaphylococcus aureusis a gram-positive pathogen responsible for life-threatening infections that are difficult to treat due to antibiotic resistance. The identification of new vulnerabilities in essential processes like cell envelope biogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c213763732d24522d879ba010f6a370
https://doi.org/10.1101/2023.04.24.538170
https://doi.org/10.1101/2023.04.24.538170
Autor:
Viktoria D. E. Schmuck, Isabelle C. Romine, Tyler A. Sisley, Chad E. Immoos, Gregory E. Scott, David F. Zigler, Andres W. Martinez
Publikováno v:
Journal of Chemical Education. 99:1081-1086
Autor:
Irina Shlosman, Elayne M. Fivenson, Morgan S.A. Gilman, Tyler A. Sisley, Suzanne Walker, Thomas G. Bernhardt, Andrew C. Kruse, Joseph J. Loparo
SummaryThe peptidoglycan (PG) cell wall protects bacteria against osmotic lysis and determines cell shape, making this structure a key antibiotic target. Peptidoglycan is a polymer of glycan chains connected by peptide crosslinks, and its synthesis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f2fcb05d0e9e14905222b9c5d77aa6
https://doi.org/10.1101/2022.11.07.515454
https://doi.org/10.1101/2022.11.07.515454
Autor:
Laurent Dubois, Sophie Helaine, Stephen A Hare, Alexander M J Hall, Rhodri M. L. Morgan, Tyler A Sisley, Rachel T. Giorgio, Grzegorz J Grabe, Julian A Rycroft
Publikováno v:
Nature Chemical Biology. 17:1296-1304
Toxin-antitoxin (TA) systems are a large family of genes implicated in the regulation of bacterial growth and its arrest in response to attacks. These systems encode nonsecreted toxins and antitoxins that specifically pair, even when present in sever
Autor:
Luke W. Koblan, Britt Adamson, Albert Xu, Mandana Arbab, Tyler A Sisley, Jordan L. Doman, Dian Yang, Joseph M. Replogle, David R. Liu, Andrew V. Anzalone, Jeffrey A. Hussmann, Max W. Shen, Gregory A. Newby, Beverly Mok, Jonathan S. Weissman
Publikováno v:
Nature Biotechnology. 39:1414-1425
Programmable C•G-to-G•C base editors (CGBEs) have broad scientific and therapeutic potential, but their editing outcomes have proved difficult to predict and their editing efficiency and product purity are often low. We describe a suite of engine
Autor:
Amy L. Rice, Celine DiBernardo, Jordan Bach, Tyler A Sisley, Scott Eagon, R. Kiplin Guy, Mofolusho O. Falade, Sierra D. Durham, Nikalet Everson, Joshua J. Kimball, Dylan R. Pillai, Michael J. Walls, Jared T. Hammill, Horacio Lazaro
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(21)
A series of tetrahydro-β-carboline derivatives of a lead compound known to target the heat shock 90 protein of Plasmodium falciparum were synthesized and assayed for both potency against the parasite and toxicity against a human cell line. Using a r
Publikováno v:
Portable Biosensors and Point-of-Care Systems ISBN: 9781849199629
This chapter will provide an overview of existing diagnostic devices made primarily out of paper and then focus on paper-based microfluidic devices, the next generation of paper-based diagnostic devices that promises to extend the use of paper as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc5c8983df2410ba3c4ad7872503690a
https://doi.org/10.1049/pbhe003e_ch2
https://doi.org/10.1049/pbhe003e_ch2