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pro vyhledávání: '"Tyler A Joseph"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007917 (2020)
Dynamic changes in microbial communities play an important role in human health and disease. Specifically, deciphering how microbial species in a community interact with each other and their environment can elucidate mechanisms of disease, a problem
Externí odkaz:
https://doaj.org/article/5240174de84743169bdf1c704a15c5ff
Autor:
Terrence C Demos, Julian C Kerbis Peterhans, Tyler A Joseph, John D Robinson, Bernard Agwanda, Michael J Hickerson
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0131800 (2015)
The Eastern Afromontane biodiversity hotspot (EABH) has the highest concentration of biodiversity in tropical Africa, yet few studies have investigated recent historical diversification processes in EABH lineages. Herein, we analyze restriction-site
Externí odkaz:
https://doaj.org/article/8a7fab6947954e65b362e5019eb7060b
Publikováno v:
Genome Research. 32:558-568
Patterns of sequencing coverage along a bacterial genome—summarized by a peak-to-trough ratio (PTR)—have been shown to accurately reflect microbial growth rates, revealing a new facet of microbial dynamics and host–microbe interactions. Here, w
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
mSystems
mSystems
The gut microbiome is spatially heterogeneous, with environmental niches contributing to the distribution and composition of microbial populations. A recently developed mapping technology, MaPS-seq, aims to characterize the spatial organization of th
Autor:
Itsik Pe'er, Tyler A. Joseph
Publikováno v:
The American Journal of Human Genetics. 105:317-333
Sequencing ancient DNA can offer direct probing of population history. Yet, such data are commonly analyzed with standard tools that assume DNA samples are all contemporary. We present DyStruct, a model and inference algorithm for inferring shared an
Autor:
Leah Briscoe, Eran Halperin, David Bogumil, Ori Furman, Itsik Pe'er, Tyler A. Joseph, Itzhak Mizrahi, Michael Thompson, Liat Shenhav
Publikováno v:
Nat Methods
Nature methods, vol 16, iss 7
Nature methods, vol 16, iss 7
A major challenge of analyzing the compositional structure of microbiome data is identifying its potential origins. Here, we introduce fast expectation-maximization microbial source tracking (FEAST), a ready-to-use scalable framework that can simulta
Autor:
Tyler A, Joseph, Itsik, Pe'er
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2243
Microbial communities are found across diverse environments, including within and across the human body. As many microbes are unculturable in the lab, much of what is known about a microbiome-a collection of bacteria, fungi, archaea, and viruses inha
Patterns of sequencing coverage along a bacterial genome—summarized by a peak-to-trough ratio (PTR)—have been shown to accurately reflect microbial growth rates, revealing a new facet of microbial dynamics and host-microbe interactions. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cc21a826ebddca927f3ec694b37f2e
https://doi.org/10.1101/2021.02.02.429365
https://doi.org/10.1101/2021.02.02.429365
Autor:
Tyler A. Joseph, Itsik Pe'er
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611029
Microbial communities are found across diverse environments, including within and across the human body. As many microbes are unculturable in the lab, much of what is known about a microbiome-a collection of bacteria, fungi, archaea, and viruses inha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::169b7b78e735c1ec51d75888c389d477
https://doi.org/10.1007/978-1-0716-1103-6_6
https://doi.org/10.1007/978-1-0716-1103-6_6
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007917 (2020)
PLoS Computational Biology
PLoS Computational Biology
Dynamic changes in microbial communities play an important role in human health and disease. Specifically, deciphering how microbial species in a community interact with each other and their environment can elucidate mechanisms of disease, a problem