Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tyler A, Cunningham"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101919- (2022)
Summary: Here, we present a protocol using MATRIX (mass spectrometry analysis of active translation factors using ribosome density fractionation and isotopic labeling experiments) platform to investigate changes of the protein synthesis machinery in
Externí odkaz:
https://doaj.org/article/972dceb72d1442c1adaf3ad258bb3094
Autor:
Derek J. Essegian, Tyler A. Cunningham, Christopher J. Zerio, Eli Chapman, Jonathan Schatz, Stephan C. Schürer
Publikováno v:
ACS Omega, Vol 6, Iss 38, Pp 24432-24443 (2021)
Externí odkaz:
https://doaj.org/article/7980bb329b004d37b04673cf8626bb3d
Autor:
Jonathan H. Schatz, Derek J. Essegian, Tyler A. Cunningham, Christopher J. Zerio, Stephan C. Schürer, Eli Chapman
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 38, Pp 24432-24443 (2021)
ACS Omega, Vol 6, Iss 38, Pp 24432-24443 (2021)
eIF4A1 is an ATP-dependent RNA helicase whose overexpression and activity have been tightly linked to oncogenesis in a number of malignancies. An understanding of the complex kinetics and conformational changes of this translational enzyme is necessa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febfe76a4d9543d2866f5b93d0cc8856
http://europepmc.org/articles/PMC8482399
http://europepmc.org/articles/PMC8482399
Autor:
Yubo Tan, Christina Phelps, Tyler W. Cunningham, Catherine D. Krawczeski, John David Spencer, Shasha Bai, Andrew R. Yates
Publikováno v:
Cardiology in the Young. 31:414-420
Objective:Acute kidney injury leads to worse outcomes following paediatric cardiac surgery. There is a lack of literature focusing on acute kidney injury after the Hybrid stage 1 palliation for single ventricle physiology. Patients undergoing the Hyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a5a25e4079f7f1406849489fc82002
https://doi.org/10.1017/s1047951120004199
https://doi.org/10.1017/s1047951120004199
Autor:
Donna D. Zhang, Matthew Dodson, Kohlson T Moore, Taoda Shi, Stephan C. Schürer, Thomas Buckley, Tyler A. Cunningham, Eli Chapman, Christopher J. Zerio, Jared Sivinski, Allison S Tulino, Derek J. Essegian, Nathan C Wilson, Jonathan H. Schatz, Erin A Alimusa, Andrew J. Ambrose
Publikováno v:
Journal of medicinal chemistry. 64(21)
Increased protein synthesis is a requirement for malignant growth, and as a result, translation has become a pharmaceutical target for cancer. The initiation of cap-dependent translation is enzymatically driven by the eukaryotic initiation factor (eI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c69e44aba3887b849e36ae7719eda5
https://pubmed.ncbi.nlm.nih.gov/34676755
https://pubmed.ncbi.nlm.nih.gov/34676755
Autor:
Tyler A. Cunningham, Priyanka Maiti, Paola Manara, Vivek Singh, Nigel Beaton, Alexey Amunts, Flavia Fontanesi, Antonio Barrientos, Jonathan H. Schatz
Publikováno v:
Blood. 140:7819-7819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::834d60ac2f0299729b5f874ddc3240d3
https://doi.org/10.1182/blood-2022-166899
https://doi.org/10.1182/blood-2022-166899
Publikováno v:
Blood. 140:8844-8844
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797414b75e203b35a4fdd1e79da7b86a
https://doi.org/10.1182/blood-2022-166771
https://doi.org/10.1182/blood-2022-166771
Autor:
Tyler W. Cunningham, Mark C. Johnson, Swati Choudhry, Brian P. Hackett, Philip T. Levy, Gautam K. Singh, Amber Salter
Publikováno v:
Journal of Perinatology. 38:543-549
Left ventricular (LV) hypertrophy (LVH) predicts adverse cardiac events in adults. We sought to determine the risk factors and prognostic significance of altered LV geometry in preterm infants. In an echocardiographic, single-center, retrospective ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d005be0087e33b07b5595f44af2fedb
https://doi.org/10.1038/s41372-018-0047-5
https://doi.org/10.1038/s41372-018-0047-5
Publikováno v:
Echocardiography. 36:1434-1436
An 8-year-old boy with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collaterals status post complete repair including a fenestrated ventricular septal defect patch presented to the catheterization laboratory for fenestration closu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81aeb21964c2a808afe864fd10f3301d
https://doi.org/10.1111/echo.14390
https://doi.org/10.1111/echo.14390
Publikováno v:
Blood. 138:4342-4342
Targeted signaling inhibitors for hematologic malignancies may lead to limited clinical efficacy due to the outgrowth of subpopulations with alternative pathways independent of the drug target. Relapse/refractory disease that results from treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e7a1f4ef0f64a88e96441deeaf18f06
https://doi.org/10.1182/blood-2021-153347
https://doi.org/10.1182/blood-2021-153347