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Classification of Predictors of Rapid Development of Kidney Failure and Short-Term Changes in Concentration of Circulating Proteins.

Autor: Kobayashi H; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Nephrology, Hypertension, and Endocrinology, Nihon University School of Medicine, Tokyo, Japan., Looker HC; Chronic Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA., Ihara K; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Md Dom ZI; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Satake E; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Tye SC; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Duffin KL; Diabetes and Complication Department, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Doria A; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Nelson RG; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA., Krolewski AS; Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.

Publikováno v: Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2024 Oct 31. Date of Electronic Publication: 2024 Oct 31.

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.

Autor: Tobias DK; Division of Preventative Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Merino J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ahmad A; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden., Aiken C; Department of Obstetrics and Gynaecology, The Rosie Hospital, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK., Benham JL; Departments of Medicine and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Bodhini D; Department of Molecular Genetics, Madras Diabetes Research Foundation, Chennai, India., Clark AL; Division of Pediatric Endocrinology, Department of Pediatrics, Saint Louis University School of Medicine, SSM Health Cardinal Glennon Children's Hospital, St. Louis, MO, USA., Colclough K; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Corcoy R; CIBER-BBN, ISCIII, Madrid, Spain.; Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain.; Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain., Cromer SJ; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Duan D; Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Felton JL; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Francis EC; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA., Gillard P; University Hospital Leuven, Leuven, Belgium., Gingras V; Department of Nutrition, Université de Montréal, Montreal, Quebec, Quebec, Canada.; Research Center, Sainte-Justine University Hospital Center, Montreal, Quebec, Quebec, Canada., Gaillard R; Department of Pediatrics, Erasmus Medical Center, Rotterdam, the Netherlands., Haider E; Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK., Hughes A; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Ikle JM; Department of Pediatrics, Stanford School of Medicine, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford School of Medicine, Stanford University, Stanford, CA, USA., Jacobsen LM; University of Florida, Gainesville, FL, USA., Kahkoska AR; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Kettunen JLT; Helsinki University Hospital, Abdominal Centre/Endocrinology, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland., Kreienkamp RJ; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Pediatrics, Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA., Lim LL; Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; Asia Diabetes Foundation, Hong Kong SAR, China.; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China., Männistö JME; Departments of Pediatrics and Clinical Genetics, Kuopio University Hospital, Kuopio, Finland.; Department of Medicine, University of Eastern Finland, Kuopio, Finland., Massey R; Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK., Mclennan NM; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Miller RG; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA., Morieri ML; Metabolic Disease Unit, University Hospital of Padova, Padova, Italy.; Department of Medicine, University of Padova, Padova, Italy., Most J; Department of Orthopedics, Zuyderland Medical Center, Sittard-Geleen, The Netherlands., Naylor RN; Departments of Pediatrics and Medicine, University of Chicago, Chicago, IL, USA., Ozkan B; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins School of Medicine, Baltimore, MD, USA., Patel KA; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Pilla SJ; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Prystupa K; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Raghavan S; Section of Academic Primary Care, US Department of Veterans Affairs Eastern Colorado Health Care System, Aurora, CO, USA.; Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA., Rooney MR; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Schön M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Diabetes Research and Metabolic Diseases (IDM), Helmholtz Center Munich, Neuherberg, Germany.; Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia., Semnani-Azad Z; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Sevilla-Gonzalez M; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA., Svalastoga P; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, Bergen, Norway., Takele WW; Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia., Tam CH; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China., Thuesen ACB; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tosur M; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Division of Pediatric Diabetes and Endocrinology, Texas Children's Hospital, Houston, TX, USA.; Children's Nutrition Research Center, USDA/ARS, Houston, TX, USA., Wallace AS; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Wang CC; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Wong JJ; Stanford University School of Medicine, Stanford, CA, USA., Yamamoto JM; Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada., Young K; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Amouyal C; Department of Diabetology, APHP, Paris, France.; Sorbonne Université, INSERM, NutriOmic team, Paris, France., Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bonham MP; Department of Nutrition, Dietetics and Food, Monash University, Melbourne, Victoria, Australia., Chen M; Monash Centre for Health Research and Implementation, Monash University, Clayton, Victoria, Australia., Cheng F; Health Management Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China., Chikowore T; Department of Medicine, Harvard Medical School, Boston, MA, USA.; MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Chivers SC; Department of Women and Children's Health, King's College London, London, UK., Clemmensen C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dabelea D; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Dawed AY; Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK., Deutsch AJ; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Dickens LT; Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Kovler Diabetes Center, University of Chicago, Chicago, IL, USA., DiMeglio LA; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA., Dudenhöffer-Pfeifer M; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden., Evans-Molina C; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA.; Richard L. Roudebush VAMC, Indianapolis, IN, USA., Fernández-Balsells MM; Biomedical Research Institute Girona, IdIBGi, Girona, Spain.; Diabetes, Endocrinology and Nutrition Unit Girona, University Hospital Dr Josep Trueta, Girona, Spain., Fitipaldi H; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden., Fitzpatrick SL; Institute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA., Gitelman SE; University of California at San Francisco, Department of Pediatrics, Diabetes Center, San Francisco, CA, USA., Goodarzi MO; Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Grieger JA; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia., Guasch-Ferré M; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Public Health and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Habibi N; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Huang C; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Harris-Kawano A; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Ismail HM; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Hoag B; Division of Endocrinology and Diabetes, Department of Pediatrics, Sanford Children's Hospital, Sioux Falls, SD, USA.; University of South Dakota School of Medicine, E Clark St, Vermillion, SD, USA., Johnson RK; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Epidemiology, Colorado School of Public Health, Aurora, CO, USA., Jones AG; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Koivula RW; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Leong A; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Leung GKW; Department of Nutrition, Dietetics and Food, Monash University, Melbourne, Victoria, Australia., Libman IM; UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Liu K; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Long SA; Center for Translational Immunology, Benaroya Research Institute, Seattle, WA, USA., Lowe WL Jr; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Morton RW; Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Translational Medicine, Medical Science, Novo Nordisk Foundation, Hellerup, Denmark., Motala AA; Department of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa., Onengut-Gumuscu S; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Pathirana M; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia., Pazmino S; Department of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinologyó, KU Leuven, Leuven, Belgium., Perez D; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Petrie JR; School of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Powe CE; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Quinteros A; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Jain R; Sanford Children's Specialty Clinic, Sioux Falls, SD, USA.; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA., Ray D; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Ried-Larsen M; Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark.; Institute for Sports and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark., Saeed Z; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Indiana University School of Medicine, Indianapolis, IN, USA., Santhakumar V; Division of Preventative Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Kanbour S; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.; AMAN Hospital, Doha, Qatar., Sarkar S; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Monaco GSF; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, University School of Medicine, Indianapolis, IN, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Scholtens DM; Department of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Selvin E; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Sheu WH; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Taiwan.; Divsion of Endocrinology and Metabolism, Taichung Veterans General Hospital, Taichung, Taiwan.; Division of Endocrinology and Metabolism, Taipei Veterans General Hospital, Taipei, Taiwan., Speake C; Center for Interventional Immunology, Benaroya Research Institute, Seattle, WA, USA., Stanislawski MA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Steenackers N; Department of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinologyó, KU Leuven, Leuven, Belgium., Steck AK; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Stefan N; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Diabetes Research and Metabolic Diseases (IDM), Helmholtz Center Munich, Neuherberg, Germany.; University Hospital of Tübingen, Tübingen, Germany., Støy J; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark., Taylor R; University of Newcastle, Newcastle upon Tyne, UK., Tye SC; Sections on Genetics and Epidemiology, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, the Netherlands., Ukke GG; Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia., Urazbayeva M; Division of Pediatric Diabetes and Endocrinology, Texas Children's Hospital, Houston, TX, USA.; Gastroenterology, Baylor College of Medicine, Houston, TX, USA., Van der Schueren B; Department of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinologyó, KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium., Vatier C; Sorbonne University, Inserm U938, Saint-Antoine Research Centre, Institute of Cardiometabolism and Nutrition, Paris, France.; Department of Endocrinology, Diabetology and Reproductive Endocrinology, Assistance Publique-Hôpitaux de Paris, Saint-Antoine University Hospital, National Reference Center for Rare Diseases of Insulin Secretion and Insulin Sensitivity (PRISIS), Paris, France., Wentworth JM; Royal Melbourne Hospital Department of Diabetes and Endocrinology, Parkville, Victoria, Australia.; Walter and Eliza Hall Institute, Parkville, Victoria, Australia.; University of Melbourne Department of Medicine, Parkville, Victoria, Australia., Hannah W; Deakin University, Melbourne, Victoria, Australia.; Department of Epidemiology, Madras Diabetes Research Foundation, Chennai, India., White SL; Department of Women and Children's Health, King's College London, London, UK.; Department of Diabetes and Endocrinology, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK., Yu G; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Zhang Y; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Zhou SJ; Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.; School of Agriculture, Food and Wine, University of Adelaide, Adelaide, South Australia, Australia., Beltrand J; Institut Cochin, Inserm U 10116, Paris, France.; Pediatric Endocrinology and Diabetes, Hopital Necker Enfants Malades, APHP Centre, Université de Paris, Paris, France., Polak M; Institut Cochin, Inserm U 10116, Paris, France.; Pediatric Endocrinology and Diabetes, Hopital Necker Enfants Malades, APHP Centre, Université de Paris, Paris, France., Aukrust I; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., de Franco E; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Flanagan SE; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Maloney KA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., McGovern A; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Molnes J; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., Nakabuye M; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Njølstad PR; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, Bergen, Norway., Pomares-Millan H; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden.; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., Provenzano M; Nephrology, Dialysis and Renal Transplant Unit, IRCCS-Azienda Ospedaliero-Universitaria di Bologna, Alma Mater Studiorum University of Bologna, Bologna, Italy., Saint-Martin C; Department of Medical Genetics, AP-HP Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France., Zhang C; Global Center for Asian Women's Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Zhu Y; Kaiser Permanente Northern California Division of Research, Oakland, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Auh S; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., de Souza R; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., Fawcett AJ; Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Clinical and Organizational Development, Chicago, IL, USA., Gruber C; American Diabetes Association, Arlington, VA, USA., Mekonnen EG; College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium., Mixter E; Department of Medicine and Kovler Diabetes Center, University of Chicago, Chicago, IL, USA., Sherifali D; Population Health Research Institute, Hamilton, Ontario, Canada.; School of Nursing, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., Eckel RH; Division of Endocrinology, Metabolism, Diabetes, University of Colorado, Aurora, CO, USA., Nolan JJ; Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.; Department of Endocrinology, Wexford General Hospital, Wexford, Ireland., Philipson LH; Department of Medicine and Kovler Diabetes Center, University of Chicago, Chicago, IL, USA., Brown RJ; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Billings LK; Division of Endocrinology, NorthShore University HealthSystem, Skokie, IL, USA.; Department of Medicine, Prtizker School of Medicine, University of Chicago, Chicago, IL, USA., Boyle K; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Costacou T; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA., Dennis JM; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Florez JC; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gloyn AL; Department of Pediatrics, Stanford School of Medicine, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford School of Medicine, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford School of Medicine, Stanford University, Stanford, CA, USA., Gomez MF; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden.; Faculty of Health, Aarhus University, Aarhus, Denmark., Gottlieb PA; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Greeley SAW; Departments of Pediatrics and Medicine and Kovler Diabetes Center, University of Chicago, Chicago, IL, USA., Griffin K; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA.; Sanford Research, Sioux Falls, SD, USA., Hattersley AT; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Hirsch IB; University of Washington School of Medicine, Seattle, WA, USA., Hivert MF; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Department of Medicine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada., Hood KK; Stanford University School of Medicine, Stanford, CA, USA., Josefson JL; Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kwak SH; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Laffel LM; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA., Lim SS; Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia., Loos RJF; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ma RCW; Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China., Mathieu C; University Hospital Leuven, Leuven, Belgium., Mathioudakis N; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Meigs JB; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA., Misra S; Division of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department of Diabetes & Endocrinology, Imperial College Healthcare NHS Trust, London, UK., Mohan V; Department of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, Chennai, India., Murphy R; Department of Medicine, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.; Auckland Diabetes Centre, Te Whatu Ora Health New Zealand, Auckland, New Zealand.; Medical Bariatric Service, Te Whatu Ora Counties, Health New Zealand, Auckland, New Zealand., Oram R; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK., Ozanne SE; University of Cambridge, Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, Cambridge, UK., Pearson ER; Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK., Perng W; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Pollin TI; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA., Pop-Busui R; Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI, USA., Pratley RE; 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Publikováno v: Nature medicine [Nat Med] 2023 Oct; Vol. 29 (10), pp. 2438-2457. Date of Electronic Publication: 2023 Oct 05.

Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure.

Autor: Tye SC; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands., Jongs N; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands., Coca SG; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sundström J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; The George Institute for Global Health, UNSW Sydney, Sydney, NSW, Australia., Arnott C; The George Institute for Global Health, UNSW Sydney, Sydney, NSW, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia., Neal B; The George Institute for Global Health, UNSW Sydney, Sydney, NSW, Australia., Perkovic V; The George Institute for Global Health, UNSW Sydney, Sydney, NSW, Australia., Mahaffey KW; Stanford Center for Clinical Research, Department of Medicine, Stanford University, Stanford, CA, USA., Vart P; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands., Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands. h.j.lambers.heerspink@umcg.nl.; The George Institute for Global Health, UNSW Sydney, Sydney, NSW, Australia. h.j.lambers.heerspink@umcg.nl.

Publikováno v: Cardiovascular diabetology [Cardiovasc Diabetol] 2022 Sep 23; Vol. 21 (1), pp. 194. Date of Electronic Publication: 2022 Sep 23.