Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Tycho M Hoogland"'
Autor:
Sebastián Loyola, Tycho M Hoogland, Hugo Hoedemaker, Vincenzo Romano, Mario Negrello, Chris I De Zeeuw
Publikováno v:
eLife, Vol 12 (2023)
The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important role in both short-term and long-term coordination o
Externí odkaz:
https://doaj.org/article/fe408a7b3a35414d8395bc5dbc4167b9
Autor:
Andres de Groot, Bastijn JG van den Boom, Romano M van Genderen, Joris Coppens, John van Veldhuijzen, Joop Bos, Hugo Hoedemaker, Mario Negrello, Ingo Willuhn, Chris I De Zeeuw, Tycho M Hoogland
Publikováno v:
eLife, Vol 9 (2020)
Miniaturized fluorescence microscopes (miniscopes) have been instrumental to monitor neural signals during unrestrained behavior and their open-source versions have made them affordable. Often, the footprint and weight of open-source miniscopes is sa
Externí odkaz:
https://doaj.org/article/276ffb5d3f42450e93f85febd7147aae
Autor:
Vincenzo Romano, Licia De Propris, Laurens WJ Bosman, Pascal Warnaar, Michiel M ten Brinke, Sander Lindeman, Chiheng Ju, Arthiha Velauthapillai, Jochen K Spanke, Emily Middendorp Guerra, Tycho M Hoogland, Mario Negrello, Egidio D'Angelo, Chris I De Zeeuw
Publikováno v:
eLife, Vol 7 (2018)
Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learned changes in motor output is largely unknown. We developed a sensory-driven adaptation protocol for reflexive whisker protraction and recorded Purkin
Externí odkaz:
https://doaj.org/article/02283eaec87d4a6a87a0f4dae31b98cb
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
The cerebellum refines the accuracy and timing of motor performance. How it encodes information to perform these functions is a major topic of interest. We performed whole cell and extracellular recordings of Purkinje cells (PCs) and cerebellar nucle
Externí odkaz:
https://doaj.org/article/e824fc35cc1b48dcbb85dec8085c25c7
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42650 (2012)
Excitatory drive enters the cerebellum via mossy fibers, which activate granule cells, and climbing fibers, which activate Purkinje cell dendrites. Until now, the coordinated regulation of these pathways has gone unmonitored in spatially resolved neu
Externí odkaz:
https://doaj.org/article/763e4d62e33148bd960621f059d8c0bb
Autor:
Sebastián Loyola, Tycho M. Hoogland, Mario Negrello, Hugo Hoedemaker, Vincenzo Romano, Chris I. De Zeeuw
The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important role in both short-term and long-term coordination o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a900a25bcd4f2b70fa8c1430704a1899
https://doi.org/10.1101/2022.09.04.506491
https://doi.org/10.1101/2022.09.04.506491
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110362-(2022)
Cell Reports, Vol 37, Iss 11, Pp 110116-(2021)
Cell Reports, 37(11):110116. Cell Press
Cell Reports, 37(11). Cell Press
Cell Reports, Vol 37, Iss 11, Pp 110116-(2021)
Cell Reports, 37(11):110116. Cell Press
Cell Reports, 37(11). Cell Press
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain. Here, we explore whether cerebellar Purkinje cells e
Autor:
Nico A Flierman, Si-Yang Yu, Maarten Kamermans, Sebastian Loyola, Chris I. De Zeeuw, Tycho M. Hoogland, XiaoLe Liu
Publikováno v:
Frontiers in cellular neuroscience, 15:621252. Frontiers Media S.A.
Frontiers in Cellular Neuroscience, 15. Frontiers Media SA
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, 15:621252. Frontiers Media S.A.
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience, 15. Frontiers Media SA
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, 15:621252. Frontiers Media S.A.
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Animal pose estimation tools based on deep learning have greatly improved animal behaviour quantification. These tools perform pose estimation on individual video frames, but do not account for variability of animal body shape in their prediction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb87ceb62026dc32377946d12cbeba3
https://pure.amc.nl/en/publications/optiflex-multiframe-animal-pose-estimation-combining-deep-learning-with-optical-flow(d5302533-df4d-419c-b46a-f9f44543ae53).html
https://pure.amc.nl/en/publications/optiflex-multiframe-animal-pose-estimation-combining-deep-learning-with-optical-flow(d5302533-df4d-419c-b46a-f9f44543ae53).html
Autor:
Sebastian Loyola, Nikolay Medvedev, Ben Torben-Nielsen, Mario Negrello, Nora Vrieler, Marylka Uusisaari, Chris I. De Zeeuw, Yosef Yarom, Yasmin Yarden-Rabinowitz, Jesse Hoogendorp, Tycho M. Hoogland, Erik De Schutter
Publikováno v:
Brain Structure & Function
Brain Structure & Function, 224(4), 1677-1695. Springer-Verlag
Brain Structure & Function, 224, 1677-1695. Springer Verlag GmbH
Brain Structure & Function, 224(4), 1677-1695. Springer-Verlag
Brain Structure & Function, 224, 1677-1695. Springer Verlag GmbH
The inferior olive (IO) is an evolutionarily conserved brain stem structure and its output activity plays a major role in the cerebellar computation necessary for controlling the temporal accuracy of motor behavior. The precise timing and synchroniza
The cerebellum is involved in cognition next to motor coordination. During complex tasks, climbing fiber input to the cerebellum can deliver seemingly opposite signals, covering both motor and non-motor functions. To elucidate this ambiguity, we hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a9174e7155af15b8b496d7b08ef1ab
https://doi.org/10.1101/2020.09.26.314534
https://doi.org/10.1101/2020.09.26.314534