Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Two-pore channel"'
Autor:
Ali Hanbashi, Moureq Alotaibi, Homood M. As Sobeai, Lama Binobaid, Khalid Alhazzani, Xuhui Jin, Faroq Kamli, Ali Alhoshani, John Parrington
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Melanoma, a severe form of skin cancer, poses significant health risks due to its aggressive nature and potential for metastasis. The role of two-pore channel 2 (TPC2) in the development and progression of melanoma remains poorly
Externí odkaz:
https://doaj.org/article/550de1cc465e475e8efd051df555c54e
Autor:
Benjamin Chun-Kit Tong, Alexis Shiying Huang, Aston Jiaxi Wu, Ashok Iyaswamy, Olivia Ka-Yi Ho, Anna Hau-Yee Kong, Sravan Gopalkrishnashetty Sreenivasmurthy, Zhou Zhu, Chengfu Su, Jia Liu, Juxian Song, Min Li, King-Ho Cheung
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-19 (2022)
Abstract Background Tauopathies are neurodegenerative diseases that are associated with the pathological accumulation of tau-containing tangles in the brain. Tauopathy can impair cognitive and motor functions and has been observed in Alzheimer’s di
Externí odkaz:
https://doaj.org/article/6edbad36a8ed4f1cb6143dc98ca27f33
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Macropinocytosis is a unique type of endocytosis accompanied by membrane ruffle formation. Closure of membrane ruffles leads to the uptake of large volumes of fluid phase and, subsequently, the formation of large vacuoles termed macropinosomes. Immun
Externí odkaz:
https://doaj.org/article/ba1781388cb346eb9856f1917b2e15a1
Akademický článek
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Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Two-pore channels (TPCs) release Ca2+ from acidic intracellular stores and are implicated in a number of diseases, but their role in development is unclear. The social amoeba Dictyostelium discoideum proliferates as single cells t
Externí odkaz:
https://doaj.org/article/fa8578a9d7864780b2d1b889c50d0c79
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 1 (2022)
The importance of Ca2+ signaling, and particularly Ca2+ channels, in key events of cancer cell function such as proliferation, metastasis, autophagy and angiogenesis, has recently begun to be appreciated. Of particular note are two-pore channels (TPC
Externí odkaz:
https://doaj.org/article/8280ab16866b46a7814051cb21461546
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Timothy F. Walseth, Andreas H. Guse
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Nicotinic acid adenine dinucleotide 2’-phosphate (NAADP) is a naturally occurring nucleotide that has been shown to be involved in the release of Ca2+ from intracellular stores in a wide variety of cell types, tissues and organisms. Current evidenc
Externí odkaz:
https://doaj.org/article/76fa38e63779414ba0fcab6ae46e973b
Publikováno v:
Cells, Vol 11, Iss 9, p 1465 (2022)
Two-pore channels (TPCs) are ligand-gated cation-selective ion channels that are preserved in plant and animal cells. In the latter, TPCs are located in membranes of acidic organelles, such as endosomes, lysosomes, and endolysosomes. Here, we focus o
Externí odkaz:
https://doaj.org/article/427d966c0021464a8c568bd4c22aa8ca
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as coronavirus disease 2019 (COVID-19) with symptoms and consequences including acute res
Externí odkaz:
https://doaj.org/article/1f2c4380f754404f81a51472d7762076