Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Two-hit hypothesis"'
Autor:
Lorenz S. Neuwirth, Kerry Whigham
Publikováno v:
Youth, Vol 3, Iss 4, Pp 1212-1224 (2023)
The peak of the coronavirus-19 (COVID-19) in New York City significantly impacted communities that lived in the New York City Housing Authority (NYCHA). However, these same communities have been historically reported to test positive for lead poisoni
Externí odkaz:
https://doaj.org/article/b6a35f739d4e49748ad6293e5a646fe9
Autor:
Shweta Parakh, Shrey Maheshwari, Shrutanjoy Das, Hans Vaish, Gaurav Luthra, Rupesh Agrawal, Vishali Gupta, Saurabh Luthra
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Purpose To report a case of central retinal vein occlusion (CRVO) seven days following the first dose of ChAdOx1 nCoV-19 vaccine and propose a hypothesis for the possible underlying pathogenesis. Observation A 31-year-old male presented with
Externí odkaz:
https://doaj.org/article/8f64306bae994161a0dea3537f07601f
Akademický článek
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Autor:
Susanne Knorr, Lisa Rauschenberger, Uri Ramirez Pasos, Maximilian U. Friedrich, Robert L. Peach, Kathrin Grundmann-Hauser, Thomas Ott, Aet O'Leary, Andreas Reif, Philip Tovote, Jens Volkmann, Chi Wang Ip
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105337- (2021)
TOR1A is the most common inherited form of dystonia with still unclear pathophysiology and reduced penetrance of 30–40%. ∆ETorA rats mimic the TOR1A disease by expression of the human TOR1A mutation without presenting a dystonic phenotype. We aim
Externí odkaz:
https://doaj.org/article/8c06d0bbd2204284a3bf0ac22fbea2a6
Autor:
Tzu-Chieh Hung, Nengjiang Zhao, Caoxin Huang, Suhuan Liu, Tao Liu, Wenfang Huang, Xiangbin Xu, Zhi-Liang Ji, Shuyu Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111408- (2021)
PingTang No.5 capsule (PT5), a modified Traditional Chinese Medicine (TCM) formula of Zexie Decoction, is used to treat patients with lipid metabolism disorders in our hospital. The present study was designed to investigate the mechanisms of PT5 in t
Externí odkaz:
https://doaj.org/article/09d68dcd8e40410093ad936038636344
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background According to experimental and clinical published studies, patients with keratoconus have a genetic predisposition to corneal ectasia; however, ectasia might not be activated or reactivated unless an additional stressful event trig
Externí odkaz:
https://doaj.org/article/353b5efd2a1b4e8f9336ecb4f810ca30
Autor:
Chung-Shiung Wen, Cheng-Maw Ho
Publikováno v:
European Medical Journal, Vol 3, Iss 3, Pp 40-48 (2018)
Chronic liver diseases take many forms; alcohol-related liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are two common illnesses that potentially lead to cirrhosis, liver failure, and liver cancer. It is estimated that a quarter of h
Externí odkaz:
https://doaj.org/article/66174bb8c44240408d00a9aed638c6b1
Autor:
Katarzyna Chamera, Ewa Trojan, Katarzyna Kotarska, Magdalena Szuster-Głuszczak, Natalia Bryniarska, Kinga Tylek, Agnieszka Basta-Kaim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1558 (2021)
Multiple lines of evidence support the pathogenic role of maternal immune activation (MIA) in the occurrence of the schizophrenia-like disturbances in offspring. While in the brain the homeostatic role of neuron-microglia protein systems is well docu
Externí odkaz:
https://doaj.org/article/57ded9937dec47afbb69f31609fe1a8a
Publikováno v:
Brain Sciences, Vol 5, Iss 3, Pp 275-298 (2015)
Dystrophin-glycoprotein complex (DGC) is an important structural unit in skeletal muscle that connects the cytoskeleton (f-actin) of a muscle fiber to the extracellular matrix (ECM). Several muscular dystrophies, such as Duchenne muscular dystrophy,
Externí odkaz:
https://doaj.org/article/d0668b4083bc40009fa60c74b98eaffb